169
Views
22
CrossRef citations to date
0
Altmetric
Research Article

Encapsulation of podophyllotoxin and etoposide in biodegradable poly-d,l-lactide nanoparticles improved their anticancer activity

, , &
Pages 211-219 | Received 10 Oct 2012, Accepted 25 Jul 2013, Published online: 09 Oct 2013

References

  • Abraham GA, Gallardo A, San RJ, Fernandez-Mayoralas A, Zurita M, Vaquero J. Polymeric matrices based on graft copolymers of PCL onto acrylic backbones for releasing antitumoral drugs. J Biomed Mater Res, 2003;64A:638–47
  • Allen LM, Creaven PJ. Comparison of the human pharmacokinetics of VM-26 and VP-16, two antineoplastic epipodophyllotixin glucopyranoside derivatives. Eur J Cancer, 1975;11:697–707
  • Ataman-Onal Y, Munier S, Ganée A, Terrat C, Durand PY, Battail N, Martinon F, Le Grand R, Charles MH, Delair T, et al. Surfactant-free anionic PLA nanoparticles coated with HIV-1 p24 protein induced enhanced cellular and humoral immune responses in various animal models. J Control Rel, 2006;15:175–85
  • Bohlin L, Rosen B. Podophyllotoxin derivatives: Drug discovery and development. Drug Discov Today, 1996;1:343–51
  • Calandrelli L, De Rosa G, Errico ME, LaRotonda MI, Laurienzo P, Malinconico M, Oliva A, Quaglia F. Novel graft PLLA-based copolymers: Potential of their application to particle technology. J Biomed Mater Res, 2002;62:244–53
  • Chen CL, Uckun FM. Highly sensitive liquid chromatography–electrospray mass spectrometry (LC–MS) method for the determination of etoposide levels in human serum and plasma. J Chromatogr B, 2000;744:91–8
  • Cicek H, Tuncel A, Tuncel M, Piskin E. Degradation and drug release characteristics of monosize polyethylcyanoacrylate microspheres. J Biomater Sci Polym Ed, 1995;6:845–56
  • Fonseca C, Simões S, Gaspar R. Paclitaxel-loaded PLGA nanoparticles: Preparation, physicochemical characterization and in vitro anti-tumoral activity. J Control Rel, 2002;83:273–86
  • Fresta M, Puglisi G, Giammona G, Cavallaro G, Micali N, Furneri PM. Pefloxacine mesilate- and ofloxacin-loaded polyethylcyanoacrylate nanoparticles: Characterization of the colloidal drug carrier formulation. J Pharm Sci, 1995;84:895–902
  • Gomez-Gaete C, Tsapis N, Besnard M, Bochot A, Fatta E. Encapsulation of dexamethasone into biodegradable polymeric nanoparticles. Int J Pharm, 2007;331:153–9
  • Habd El-Mohdy HL, Ghanem S. Biodegradability, antimicrobial activity and properties of PVA/PVP hydrogels prepared by γ-irradiation. J Polym Res, 2009;16:1–10
  • Huang J, Bu L, Xie J, Chen K, Cheng Z, Li X, Chen X. Effects of nanoparticle size on cellular uptake and liver MRI with PVP-coated iron oxide nanoparticles. ACS Nano, 2010;4:7151–60
  • Italia JL, Yahya MM, Singh D, Ravi Kumar MN. Biodegradable nanoparticles improve oral bioavailability of amphotericin B and show reduced nephrotoxicity compared to intravenous Fungizone. Pharm Res, 2009;26:1324–31
  • Jiao YH, Li Y, Wang S, Zhang K, Jia YG, Yu F. Layer-by-layer assembly of poly(lactic acid) nanoparticles: A facile way to fabricate films for model drug delivery. Langmuir, 2010;26:8270–3
  • Jin C, Bai L, Wu H, Song W, Guo G, Dou K. Cytotoxicity of paclitaxel incorporated in PLGA nanoparticles on hypoxic human tumor cells. Pharm Res, 2009;26:1776–84
  • Kao WF, Hung DZ, Tsai WJ, Lin KP, Deng JF. Podophyllotoxin intoxication: Toxic effect of bajiaolian in herbal therapeutics. Hum Exp Toxicol, 1992;11:480–7
  • Kim TH, Jiang HH, Youn YS, Park CW, Tak KK, Lee S, Kim H, Jon S, Chen X, Lee KC. Preparation and characterization of water-soluble albumin-bound curcumin nanoparticles with improved antitumor activity. Int J Pharm, 2011;403:285–91
  • Kumar V, Yadav SC, Yadav SK. Syzygium cumini leaf and seed extract mediated biosynthesis of silver nanoparticles and their characterization. J Chem Tech Biotech, 2010;85:1301–9
  • Kumari A, Kumar V, Yadav SK. Plant extract synthesized PLA nanoparticles for controlled and sustained release of quercetin: A green approach. PLoS One, 2012;7:e41230
  • Kumari A, Yadav SK. Cellular interactions of therapeutically delivered nanoparticles. Expert Opin Drug Del, 2011;8:141–51
  • Kumari A, Yadav SK, Pakade YB, Kumar V, Singh B, Chaudhary A, Yadav SC. Nanoencapsulation and characterization of Albizia chinensis isolated antioxidant quercitrin on PLA nanoparticles. Colloid Surface B, 2011;82:224–32
  • Kumari A, Yadav SK, Pakade YB, Singh B, Yadav SC. Development of biodegradable nanoparticles for delivery of quercetin. Colloid Surface B, 2010a;80:184–92
  • Kumari A, Yadav SK, Yadav SC. Biodegradable polymeric nanoparticles based drug delivery systems. Colloid Surface B, 2010b;75:1–18
  • Lamprecht A, Benoit JP. Etoposide nanocarriers suppress glioma cell growth by intracellular drug delivery and simultaneous P-glycoprotein inhibition. J Control Rel, 2006;112:208–13
  • Lamprecht A, Schafer U, Lehr CM. Size-dependent bioadhesion of micro- and nanoparticulate carriers to the inflamed colonic mucosa. Pharm Res, 2001;18:788–93
  • Lee K-H. Anticancer drug design based on plant-derived natural products. J Biomed Sci, 1999;6:236–50
  • Li W, Lam M, Choy D, Birkeland A, Mark ES, Post JM. Human primary renal cells as a model for toxicity assessment of chemo-therapeutic drugs. Toxicol in Vitro, 2006;20:669–76
  • Liu J, Xiao Y, Allen C. Polymer-drug compatibility: A guide to the development of delivery systems for the anticancer agent, ellipticine. J Pharm Sci, 2004;93:132–43
  • Liu YQ, Yang L, Tian X. Podophyllotoxin: Current perspective. Curr Bioact Compd, 2007;3:37–66
  • Lizama C, Ludwig A, Moreno RD. Etoposide induces apoptosis and upregulation of TACE/ADAM17 and ADAM10 in an in vitro male germ cell line model. Biochim Biophysica Acta, 2011;1813:120–8
  • Lo CL, Lin KM, Hsiue GH. Preparation and characterization of intelligent core-shell nanoparticles based on poly(d,l-lactide)-g-poly(N-isopropyl acrylamide-co-methacrylic acid). J Control Rel, 2005;104:477–88
  • Lowenthal RM, Eaton K. Toxicity of chemotherapy. Hematol Oncol Clin North Am, 1996;10:967–90
  • Luo YB, Wang X-L, Xu DY, Wang YZ. Preparation and characterization of poly (lactic acid)-grafted TiO2nanoparticles with improved dispersions. Appl Surf Sci, 2009;255:6795–801
  • Ma R, Levard C, Marinakos SM, Cheng Y, Liu J, Michel FM, Brown GE Jr, Lowry GV. Size-controlled dissolution of organic-coated silver nanoparticles. Environ Sci Technol, 2012;46:752–9
  • Mishra N, Acharya R, Gupta AP, Singh B, Kaul VK, Ahuja PS. A simple microanalytical technique for determination of podophyllotoxin in Podophyllum hexandrum roots by quantitative RP–HPLC and RP–HPTLC. Curr Sci, 2005;88:1372–3
  • Mitra M, Dilnawaz F, Misra R, Harilal A, Verma RS, Sahoo SK, Krishnakumar S. Toxicogenomics of nanoparticulate delivery of etoposide: Potential impact on nanotechnology in retinoblastoma therapy. Cancer Nano, 2011;2:21–36
  • Musumeci T, Ventura CA, Giannone I, Ruozi B, Montenegro L, Pignatello R, Puglisi G. PLA/PLGA nanoparticles for sustained release of docetaxel. Int J Pharm, 2006;15:325:172–9
  • Panyam J, Labhasetwar V. Biodegradable nanoparticles for drug and gene delivery to cells and tissue. Adv Drug Deliv Rev, 2003;55:329–47
  • Patel SR, Suthar AP, Patel RM. In vitro cytotoxicity activity of Semecarpus anacardium extract against Hep 2 cell line and Vero cell line. Int J Pharm Tech Res, 2009;1:1429–33
  • Qin L, Xue M, Wang W, Zhu R, Wang S, Sun J, Zhang R, Sun X. The in vitro and in vivo anti-tumor effect of layered double hydroxides nanoparticles as delivery for podophyllotoxin. Int J Pharm, 2010;388:223–30
  • Reddy LH, Sharma RK, Chuttani K, Mishra AK, Murthy RSR. Influence of administration route on tumor uptake and biodistribution of etoposide loaded solid lipid nanoparticles in Dalton’s lymphoma tumor bearing mice. J Control Rel, 2005;105:185–98
  • Redhead HM, Davis SS, Illum L. Drug delivery in poly(lactide-co-glycolide) nanoparticles surface modified with poloxamer 407 and poloxamine 908: in vitro characterisation and in vivo evaluation. J Control Rel, 2001;70:353–63
  • Sendo T, Teshima D, Makino K, Mishima K, Itoh Y, Oishi, R. Application of dynamic laser scattering to the quality control of injectable drugs: Polymer formation in ampicillin solution. J Clin Pharm Ther, 2002;27:79–84
  • Semete B, Booysen L, Lemmer Y, Kalombo L, Katata L, Verschoor J, Swai HS. In vivo evaluation of the biodistribution and safety of PLGA nanoparticles as drug delivery systems. Nanomed Nanotechnol Biol Med, 2010;6:662–71
  • Shakweh M, Besnard M, Nicolas V, Fattal E. Poly (lactide-co-glycolide) particles of different physicochemical properties and their uptake by Peyer’s patches in mice. Eur J Pharm Biopharm, 2005;61:1–13
  • Sompur CK, Doijad RC, Goje A. A novel approach for development and characterization of etoposide loaded solid lipid nanoparticles. Int J Pharm Bio Sci, 2011;2:298–306
  • Stadtmauer EA, Cassileth PA, Gale RP. Etoposide in leukemia, lymphoma and bone marrow transplantation. Leuk Res, 1989;13:639–50
  • Stolnik S, Davies MC, Illum L, Davis SS, Boustta M. The preparations of sub-200 nm poly (lactide-co-glycolide) microspheres for site-specific drug delivery. J Control Rel, 1993;25:145–53
  • Tsai Y-M, Chien C-F, Lin L-C, Tsai T-H. Curcumin and its nano-formulation: The kinetics of tissue distribution and blood–brain barrier penetration. Int J Pharm, 2011;416:331–8
  • Vichai V, Kirtikara K. Sulforhodamine B colorimetric assay for cytotoxicity screening. Nature Protocols, 2006;1:1112–16
  • Vlietinck SAA, Pieters L. Lignans and neolignans as lead compounds. Phytochemistry Rev, 2003;2:201–21
  • Walia M, Mann T, Kumar D, Agnihotri V, Singh B. Chemical composition and in vitro cytotoxic activity of essential oil of leaves of Malus domestica growing in western Himalaya (India). Evid Compl Alter Med, 2012;649727:1–6
  • Xing J, Zhang D, Tan T. Studies on the oridonin-loaded poly(d,l-lactic acid) nanoparticles in vitro and in vivo. Int J Biol Macromol, 2007;40:153–8
  • Yadav SK, Chuttani K, Mishra AK, Sawant KK. Long circulating nanoparticles of etoposide using PLGA-MPEG and PLGA-pluronic block copolymers: Characterization, drug-release, blood-clearance, and biodistribution studies. Drug Develop Res, 2010;71:228–39
  • Zambaux MF, Bonneaux F, Gref R, Dellacherie E, Vigneron C. Preparation and characterization of protein C-loaded PLA nanoparticles. J Control Rel, 1999;60:179–88
  • Zambaux MF, Bonneaux F, Gref R, Maincent P, Dellacherie E, Alonso MJ, Labrude P, Vigneron C. Influence of experimental parameters on the characteristics of poly (lactic acid) nanoparticles prepared by a double emulsion method. J Control Rel, 1998;50:31–40
  • Zhang T, Chen J, Zhang Y, Shen Q, Pan W. Characterization and evaluation of nanostructured lipid carrier as a vehicle for oral delivery of etoposide. Eur J Pharm Sci, 2011;43:174–9
  • Zhang Y, Chu CC. In vitro release behavior of insulin from biodegradable hybrid hydrogel networks of polysaccharide and synthetic biodegradable polyester. J Biomater Appl, 2002;16:305–25
  • Zhu RR, Qin LL, Wang M, Wu SM, Wang SL, Zang R, Liu ZX, Sun XY, Yao SD. Preparation, characterization, and anti-tumor property of podophyllotoxin-loaded solid lipid nanoparticles. Nanotechnology, 2009;20:055702

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.