255
Views
7
CrossRef citations to date
0
Altmetric
Research Article

Preparation and in vitro evaluation of surface-modified poly (lactide-co-glycolide) microparticles as biodegradable drug carriers for pulmonary peptide and protein delivery

&
Pages 355-362 | Received 09 Apr 2013, Accepted 15 Oct 2013, Published online: 03 Apr 2014

References

  • Alpar HO, Somavarapu S, Atuah KN, Bramwell VW. Biodegradable mucoadhesive particulates for nasal and pulmonary antigen and DNA delivery. Adv Drug Deliv Rev, 2005;57:411–30
  • Andrews GP, Laverty TP, Jones DS. Mucoadhesive polymeric platforms for controlled drug delivery. Eur J Pharm Biopharm, 2009;71:505–18
  • Aubert-Pouessel A, Venier-Julienne M-C, Clavreul A, Sergent M, Jollivet C, Montero-Menei CN, Garcion E, Bibby DC, Menei P, Benoit J-P. In vitro study of GDNF release from biodegradable PLGA microspheres. J Control Release, 2004;95:463–75
  • Bansil R, Stanley E, LaMont JT. Mucin biophysics. Ann Rev Physiol, 1995;57:635–57
  • Bittner B, Morlock M, Koll H, Winter G, Kissel T. Recombinant human erythropoietin (rhEPO) loaded poly(lactide-co-glycolide) microspheres: Influence of the encapsulation technique and polymer purity on microsphere characteristics. Eur J Pharm Biopharm, 1998;45(3):295–305
  • Bravo-Osuna I, Vauthier C, Farabollini A, Palmieri GF, Ponchel G. Mucoadhesion mechanism of chitosan and thiolated chitosan-poly(isobutyl cyanoacrylate) core-shell nanoparticles. Biomaterials, 2007;28:2233–43
  • Budhian A, Siegel SJ, Winey KI. Controlling the in vitro release profiles for a system of haloperidol-loaded PLGA nanoparticles. Int J Pharm, 2008;346(1–2):151–9
  • Chen H, Yang W, Chen H, Liu L, Gao F, Yang X, Jiang Q, Zhang Q, Wang Y. Surface modification of mitoxantrone-loaded PLGA nanospheres with chitosan. Colloids Surf B: Biointerfaces, 2009;73:212–18
  • Chronopoulou L, Massimi M, Giardi MF, Cametti C, Devirgiliis LC, Dentini M, Palocci C. Chitosan-coated PLGA nanoparticles: A sustained drug release strategy for cell cultures. Colloids Surf B: Biointerfaces, 2013;103:310–17
  • Dash M, Chiellini F, Ottenbrite R, Chiellini E. Chitosan -- a versatile semi-synthetic polymer in biomedical applications. Prog Polym Sci, 2011;36:981–1014
  • Den Otter W, Jacobs JJL, Battermann JJ, Hordijk GJ, Krastev Z, Moiseeva EV, Stewart RJE, Ziekman PGPM, Koten JW. Local therapy of cancer with free IL-2. Cancer Immunol Immunother, 2008;57:931–50
  • Devrim B, Bozkır A. Preparation and evaluation of double-walled microparticles prepared with a modified water-in-oil-in-oil-in-water (w1/o/o/w3) method. J Microencapsul, 2013;30(8):741--54
  • Devrim B, Bozkır A, Canefe K. Preparation and evaluation of poly(lactic-co-glycolic acid) microparticles as a carrier for pulmonary delivery of recombinant human interleukin-2: II. In vitro studies on aerodynamic properties of dry powder inhaler formulations. Drug Dev Ind Pharm, 2011a;37(11):1376–86
  • Devrim B, Bozkır A, Canefe K. Preparation and evaluation of PLGA microparticles as carrier for the pulmonary delivery of rhIL-2: I. Effects of some formulation parameters on microparticle characteristics. J Microencapsul, 2011b;28(6):582–94
  • Gonda I. The ascent of pulmonary drug delivery. J Pharm Sci, 2000;89:940–5
  • He P, Davis SS, Illum L. In vitro evaluation of the mucoadhesive properties of chitosan microspheres. Int J Pharm, 1998;166:75–88
  • Hejazi R, Amiji M. Chitosan-based gastrointestinal delivery systems. J Control Release, 2003;89:151–65
  • Illum L. Chitosan and its use as a pharmaceutical excipient. Pharm Res, 1998;15:1326–31
  • Jeong YI, Shim YH, Kim C, Lim GT, Choi KC, Yoon C. Effect of cryoprotectants on the reconstitution of surfactant-free nanoparticles of poly(dl-lactide-co-glycolide). J Microencapsul, 2005;22:593–601
  • Johansen P, Tamber H, Merkle HP, Gander B. Diphtheria and tetanus toxoid microencapsulation into conventional and end-group alkylated PLA/PLGAs. Eur J Pharm Biopharm, 1999;47:193–201
  • Kawashima Y, Yamamoto H, Takeuchi H, Kuno Y. Mucoadhesive dl-lactide/glycolide copolymer nanospheres coated with chitosan to improve oral delivery of elcatonin. Pharm Dev Technol, 2000;5:77–85
  • Kean T, Thanou M. Biodegradation, biodistribution and toxicity of chitosan. Adv Drug Deliv Rev, 2010;62:3–11
  • Kim TH, Lee H, Park TG. Pegylated recombinant human epidermal growth factor (rhEGF) for sustained release from biodegradable PLGA microspheres. Biomaterials, 2002;23:2311–17
  • Lee D-W, Shirley SA, Lockey RF, Mohapatra SS. Thiolated chitosan nanoparticles enhance anti-inflammatory effects of intranasally delivered theophylline. Respir Res, 2006;7:1–10
  • Lee ES, Park K-H, Park IS, Na K. Glycol chitosan as a stabilizer for protein encapsulated into poly(lactide-co-glycolide) microparticle. Int J Pharm, 2007;338:310–16
  • Lipworth BJ. Pharmacokinetics of inhaled drugs. Br J Clin Pharmacol, 1996;42:697–706
  • Madsen F, Eberth K, Smart JD. A rheological examination of the mucoadhesive/mucus interaction: The effect of mucoadhesive type and concentration. J Control Release, 1998;50:167–78
  • Malaekeh-Nikouei B, Sajadi Tabassi SA, Jaafari MR. Preparation, characterization, and mucoadhesive properties of chitosan-coated microspheres encapsulated with cyclosporine A. Drug Dev Ind Pharm, 2008;34:492–8
  • Manca M-L, Mourtas S, Dracopoulos V, Fadda AM, Antimisiaris SG. PLGA, chitosan or chitosan-coated PLGA microparticles for alveolar delivery? A comparative study of particle stability during nebulization. Colloids Surf B: Biointerfaces, 2008;62:220–31
  • Meng FT, Ma GH, Qiu W, Su ZG. W/O/W double emulsion technique using ethyl acetate as organic solvent: Effects of its diffusion rate on the characteristics of microparticles. J Control Release, 2003;91:407–16
  • Modi J, Joshi G, Sawant K. Chitosan based mucoadhesive nanoparticles of ketoconazole for bioavailability enhancement: Formulation, optimization, in vitro and ex vivo evaluation. Drug Dev Ind Pharm, 2013;39(4):540–7
  • Peppas NA, Huang Y. Nanoscale technology of mucoadhesive interactions. Adv Drug Deliv Rev, 2004;56:1675–87
  • Sharma R, Saxena D, Dwivedi AK, Misra A. Inhalable microparticles containing drug combinations to target alveolar macrophages for treatment of pulmonary tuberculosis. Pharm Res, 2001;18:1405–10
  • Singla AK, Chawla M, Singh A. Potential applications of carbomer in oral mucoadhesive controlled drug delivery system: A review. Drug Dev Ind Pharm, 2000; 26(9):913–24
  • Smith DJ, King WF, Barnes LA, Trantolo D, Wise DL, Taubman MA. Facilitated intranasal induction of mucosal and systemic immunity to mutans streptococcal glucosyltransferase peptide vaccines. Infect Immun, 2001;69:4767–73
  • Smyth HDC, Hickey AJ. Carriers in drug powder delivery. Implications for inhalation system design. Am J Drug Deliv, 2005;3:117–32
  • Qi L, Xu Z. In vivo antitumor activity of chitosan nanoparticles. Bioorg Med Chem Lett, 2006;16:4243–5
  • Qiang F, Shin H-J, Lee B-J, Han H-K. Enhanced systemic exposure of fexofenadine via the intranasal administration of chitosan-coated liposome. Int J Pharm, 2012;430:161–6
  • Tafaghodi M, Saluja V, Kersten GFA, Kraan H, Slütter B, Amorij J-P, Jiskoot W. Hepatitis B surface antigen nanoparticles coated with chitosan and trimethyl chitosan: Impact of formulation on physicochemical and immunological characteristics. Vaccine, 2012;30:5341–8
  • Tahara K, Sakai T, Yamamoto H, Takeuchi H, Kawashima Y. Establishing chitosan coated PLGA nanosphere platform loaded with wide variety of nucleic acid by complexation with cationic compound for gene delivery. Int J Pharm, 2008;354:210–16
  • Tahara K, Yamamoto H, Hirashima N, Kawashima Y. Chitosan-modified poly(d,l-lactide-co-glycolide) nanospheres for improving siRNA delivery and gene-silencing effects. Eur J Pharm Biopharm, 2010;74:421–6
  • Yamamoto H, Kuno Y, Sugimoto S, Takeuchi H, Kawashima Y. Surface-modified PLGA nanosphere with chitosan improved pulmonary delivery of calcitonin by mucoadhesion and opening of the intercellular tight junctions. J Control Release, 2005;102:373–81
  • Yang M, Yamamoto H, Kurashima H, Takeuchi H, Yokoyama T, Tsujimoto H, Kawashima Y. Design and evaluation of poly(dl-lactic-co-glycolic acid) nanocomposite particles containing salmon calcitonin for inhalation. Eur J Pharm Sci, 2012;46(5):374–80
  • Yang R, Yang S-G, Shim W-S, Cui F, Cheng G, Kim I-W, Kim D-D, Chung S-J, Shim C-K. Lung-specific delivery of paclitaxel by chitosan-modified PLGA nanoparticles via transient formation of microaggregates. J Pharm Sci, 2009;98:970–84
  • Zeng P, Xu Y, Zeng C, Ren H, Peng M. Chitosan-modified poly(d,l-lactide-co-glycolide) nanospheres for plasmid DNA delivery and HBV gene-silencing. Int J Pharm, 2011;415:259–66
  • Zheng CH, Gao JQ, Zhang YP, Liang WQ. A protein delivery system: Biodegradable alginate–chitosan–poly(lactic-co-glycolic acid) composite microspheres. Biochem Biophys Res Commun, 2004;323:1321–7

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.