229
Views
9
CrossRef citations to date
0
Altmetric
Research Article

Synthesis and characterisation of a pH-sensitive magnetic nanocomposite for controlled delivery of doxorubicin

, &
Pages 533-537 | Received 09 Nov 2014, Accepted 04 Jun 2015, Published online: 18 Aug 2015

References

  • Ambruosi A, Gelperina S, Khalansky A, Tanski S, Theisen A, Kreuter J. Influence of surfactants, polymer and doxorubicin loading on the anti-tumour effect of poly (butyl cyanoacrylate) nanoparticles in a rat glioma model. J Microencapsul, 2006;23(5):582–92
  • Dong X, Mumper RJ. Nanomedicinal strategies to treat multidrug-resistant tumors: Current progress. Nanomedicine, 2010;5(4):597–615
  • Du C, Deng D, Shan L, Wan S, Cao J, Tian J, Achilefu S, Gu Y. A pH-sensitive doxorubicin prodrug based on folate-conjugated BSA for tumor-targeted drug delivery. Biomaterials, 2013;34(12):3087–97
  • Fan L, Luo C, Li X, Lu F, Qiu H, Sun M. Fabrication of novel magnetic chitosan grafted with graphene oxide to enhance adsorption properties for methyl blue. J Hazard Mater, 2012;215:272–9
  • Frey NA, Peng S, Cheng K, Sun S. Magnetic nanoparticles: Synthesis, functionalization, and applications in bioimaging and magnetic energy storage. Chem Soc Rev, 2009;38(9):2532–42
  • Gao J, Ran X, Shi C, Cheng H, Cheng T, Su Y. One-step solvothermal synthesis of highly water-soluble, negatively charged superparamagnetic Fe3O4 colloidal nanocrystal clusters. Nanoscale, 2013;5(15):7026–33
  • Ghasemzadeh MA, Ghomi JS, Molaei H. Fe3O4 nanoparticles: As an efficient, green and magnetically reusable catalyst for the one-pot synthesis of 1,8-dioxo-decahydroa-cridine derivatives under solvent-free conditions. C R Chimie, 2012;15(11):969–74
  • Kansal S, Tandon R, Verma PRP, Dube A, Mishra PR. Development of doxorubicin loaded novel core shell structured nanocapsules for the intervention of visceral leishmaniasis. J Microencapsul, 2013;30(5):441–50
  • Kunjachan S, Gupta S, Dwivedi AK, Dube A, Chourasia MK. Chitosan-based macrophage-mediated drug targeting for the treatment of experimental visceral leishmaniasis. J Microencapsul, 2011;28(4):301–10
  • Kobayashi Y, Saeki S, Yoshida M, Nagao D, Konno M. Synthesis of spherical submicron sized magnetite/silica nanocomposite particles. J Sol-Gel Sci Technol, 2008;45(1):35–41
  • Laguna KM, Verwoert S, Charrois GJ, Allen TM. Determination of doxorubicin levels in whole tumor and tumor nuclei in murine breast cancer tumors. Clin Cancer Res, 2005;11(19):6944–9
  • Lee LS, Na K, Bae YH. Polymeric micelle for tumor pH and folatemediated Targeting. J Control Release, 2003;91(1):103–13
  • Li M, Neoh KG, Wang R, Zong BY, Tan JY, Kang ET. Methotrexate-conjugated and hyperbranched polyglycerol-grafted Fe3O4 magnetic nanoparticles for targeted anticancer effects. Eur J Pharm Sci, 2013;48(1-2):111–20
  • Li Y, He H, Jia X, Lu WL, Lou J, Wei Y. A dual-targeting nanocarrier based on poly(amidoamine) dendrimers conjugated with transferrin and tamoxifen for treating brain gliomas. Biomaterials, 2012;33(15):3899–908
  • Liu D, Hu H, Zhang J, Zhao X, Tang X, Chen D. Drug pH-sensitive release in vitro and targeting ability of polyamidoamine dendrimer complexes for tumor cells. Chem Pharm Bull, 2011;59(1):63–71
  • Ma M, Zhang Y, Yu W, Shen HY, Zhang HQ, Gu N. Preparation and characterization of magnetite nanoparticles coated by amino silane. Colloids Surf A: Physico-Chem Eng Aspects, 2003;212(2):219–26
  • Park JH, Im KH, Lee SH, Kim DH, Lee DY, Kim KM, Kim KN. Preparation and characterization of magnetic chitosan particles for hyperthermia application. J Magn Magn Mater, 2005;293(1):328–33
  • Shubayev VI, Pisanic TR, Jin S. Magnetic nanoparticles for theragnostics. Adv Drug Deliv Rev, 2009;61(6):467–77
  • Tang H, Guo J, Sun Y, Chang B, Ren Q, Yang W. Facile synthesis of pH sensitive polymer-coated mesoporous silica nanoparticles and their application in drug delivery. Int J Pharm, 2011;421(2):388–96
  • Wu H, Tang L, An L, Wang X, Zhang H, Shi J, Yang S. pH-responsive magnetic mesoporous silica nanospheres for magnetic resonance imaging and drug delivery. React Funct Polym, 2012;72(5):329–36
  • Yabbarov NG, Posypanova GA, Vorontsov EA, Obydenny SI, Severin ES. A new system for targeted delivery of doxorubicin into tumor cells. J Control Release, 2013;168(2):135–41
  • Yang L, Liu H. Stimuli-responsive magnetic particles and their applications in biomedical field. Powder Technol, 2013;240:54–65
  • Yu FS, Wu GL, Gu X, Wang JJ, Wang YN, Gao H, Ma JB. Magnetic and pH-sensitive nanoparticles for antitumor drug delivery. Colloids Surf B: Biointerfaces, 2013;103(1):15–22
  • Zhang DW, Das DB, Rielly CD. Microneedle assisted micro-particle delivery from gene guns: Experiments using skin-mimicking agarose. Gel J Chem Eng Sci, 2014;103:613–27

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.