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Journal of Microencapsulation
Micro and Nano Carriers
Volume 3, 1986 - Issue 4
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Research Article

Eudragit RS and RL (acrylic resins) microcapsules as pH insensitive and sustained release preparations of ketoprofen

Shigeru Goto Faculty of Pharmaceutical Sciences, Kyushyu University School of Medicine, 3-1-1 Maidashi, Higashiku, Fukuoka, 812, Japan
,
Masakazu Kawata Faculty of Pharmaceutical Sciences, Kyushyu University School of Medicine, 3-1-1 Maidashi, Higashiku, Fukuoka, 812, Japan
,
Masahiro Nakamura Faculty of Pharmaceutical Sciences, Kyushyu University School of Medicine, 3-1-1 Maidashi, Higashiku, Fukuoka, 812, Japan
,
Kaori Maekawa Faculty of Pharmaceutical Sciences, Kyushyu University School of Medicine, 3-1-1 Maidashi, Higashiku, Fukuoka, 812, Japan
&
Toshinobu Aoyama Hospital Pharmacy, Kyushyu University School of Medicine, 3-1-1 Maidashi, Higashiku, Fukuoka, 812, Japan
Pages 293-304 | Received 07 Jun 1986, Accepted 13 Jun 1986, Published online: 27 Sep 2008

References

  • Benita S., Hoffman A., Donbrow M. Microencapsulation of paracetamol using polyacrylate resins (Eudragit Retard), kinetics of drug release and evaluation of kinetic model. Journal of Pharmacy and Pharmacology 1985a; 37: 391–395
  • Benita S., Hoffman A., Donbrow M. Polyacrylate resin (Eudragit Retard) microcapsules as a controlled release drug delivery system-improved non-solvent addition phase separation process. Journal of Microencapsulation 1985b; 2: 207–222
  • El-Sayed A. A., Badawi A. A., Fouli A. M. Effect of solvent used in the preparation of solid dispersions and microcapsules on the dissolution drugs. Pharmaceutica Acta Helvetiae 1982; 57: 61–64
  • Fouli A. M., El-Sayed A. A., Badawi A. A. Release of drugs from microcapsules of methacrylate polymers. International Journal of Pharmaceutics 1983; 14: 95–102
  • Goto S., Kawata M., Nakamura M., Aoyama T. Effect of magnesium stearate in the preparation of Eudragit RS microcapsules containing drugs. Yakugaku Zasshi 1985a; 105: 1087–1095
  • Goto S., Kawata M., Nakamura M., Aoyama T. Role of metal stearates in the preparation of Eudragit RS microcapsules containing sulfamethizole by evaporation process in the water phase. Yakugaku Zasshi 1985b; 106: 60–67
  • Kawata M., Nakamura M., Goto S., Aoyama T. Preparation and dissolution pattern of Eudragit RS microcapsules containing ketoprofen. Chemical Pharmaceutical Bulletin 1986; 34: 2618–2623
  • Kitajima M., Kondo A., Morishita M., Abe J. Process for preparing a microcapsule. United States Patents, 3714065, 1973
  • Röhm Pharma Co. Information Sheets ‘Eudragit RS and RL’. 1983
  • Röhm Pharma Co. Information Sheets ‘Eudragit E’. 1982a
  • Röhm Pharma Co. Information Sheets ‘Eudragit L and S’. 1982b
  • Uchida T., Kawata M., Goto S. In vivo evaluation of ethyl cellulose microcapsules containing ampicillin using rabbits, beagle dogs and humans. Journal of Pharmacobio-Dynamics 1986; 9: 631–637
  • Ueno K., Fukunaga K., Tanaka G., Sugimoto K., Hirano Y., Ozaki T. Evaluation of dissolution and acid-resistance of L-Keflex granules. Byoin Yakugaku 1981; 7: 300–304

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