Influence of drug loading level on drug release and dynamic swelling of crosslinked gelatin microspheres

References

• Baker R.W., Lonsdale H.K. Controlled release: mechanisms and rates. Controlled Release of Biologically Active Agents, A. C. Tanquary, R. E. Lacey. Plenum Press, New York 1974; 15–71
   Google Scholar
• Bodmeier R., McGinity J.W. The preparation and evaluation of drug-containing poly (dl-lactide) microspheres formed by the solvent evaporation method. Pharmaceutical Research 1987; 4: 465–471
   PubMed Web of Science ®Google Scholar
• Davis P., Tabor B.E. Kinetic study of the crosslinking of gelatin by formaldehyde and glioxal. Journal of Polymer Science: Part A 1963; 1: 799–815
   Web of Science ®Google Scholar
• Doelker E. Propriétés des polymères et principes de préparation des systèmes médicamenteux polymériques. Formes Pharmaceutiques Nouvelles: Aspects Technologique, Biopharmaceutique et Médical, P. Buri, F. Puisieux, E. Doelker, J.-P. Benoît. Lavoisier, Paris 1985; 5–63
   Google Scholar
• Egbaria K., Friedman M. Sustained release albumin microspheres containing antibacterial drugs: effects of preparation conditions on kinetics of drug release. Journal of Controlled Release 1990; 14: 79–94
   Web of Science ®Google Scholar
• Gander B., Gurny R., Doelker E., Peppas N.A. Crosslinked poly(alkylene oxides) for the preparation of controlled release micromatrices. Journal of Controlled Release 1988; 5: 271–283
   Google Scholar
• Gander B., Gurny R., Doelker E., Peppas N.A. Effect of polymeric network structure on drug release from cross-linked poly(vinyl alcohol) micromatrices. Pharmaceutical Research 1989; 6: 578–584
   PubMed Web of Science ®Google Scholar
• Harvey S.C., Withrow C.D. Cardiovascular drugs. Remington's Pharmaceutical Sciences, 18th edn, A. R. Gennaro. Mack Publishing Co., Easton, PA 1990; 831–859
   Google Scholar
• Hashida M., Muranishi S., Sezaki H. Evaluation of water in oil and microsphere in oil emulsions as a specific delivery system of 5-fluorouracil into lymphatics. Chemical and Pharmaceutical Bulletin 1977; 25: 2410–2418
   PubMed Web of Science ®Google Scholar
• Hashida M., Muranishi S., Sezaki H., Tanigawa N., Satomura K., Hikasa Y. Increased lymphatic delivery of bleomycin by microsphere in oil emulsion and its effect of lymph node metastasis. International Journal of Pharmaceutics 1979; 2: 245–256
   Web of Science ®Google Scholar
• Hsieh D.S.T., Rhine W.D., Langer R. Zero-order controlled-release polymer matrices for micro- and macromolecules. Journal of Pharmaceutical Sciences 1983; 72: 17–22
   PubMed Web of Science ®Google Scholar
• Kaye B.H. Fractal description of fineparticle systems. Particle Characterization in Technology, Vol. I: Applications and Microanalysis, J. K. Beddow. CRC Press, Boca Raton, FL 1986; 81–100
   Google Scholar
• Korsmeyer R.W., Gurny R., Doelker E., Buri P., Peppas N.A. Mechanisms of solute release from porous hydrophilic polymers. International Journal of Pharmaceutics 1983; 15: 25–35
   Web of Science ®Google Scholar
• Langenbucher F. In vitro assessment of dissolution kinetics: description and evaluation of a column-type method. Journal of Pharmaceutical Sciences 1969; 58: 1265–1272
   PubMed Web of Science ®Google Scholar
• Lee P.I. Dimensional changes during drug release from a glassy hydrogel matrix. Polymer Communications 1983; 24: 45–47
   Web of Science ®Google Scholar
• Lee P.I. Novel approach to zero-order drug delivery via immobilized nonuniform drug distribution in glassy hydrogels. Journal of Pharmaceutical Sciences 1984; 73: 1344–1347
   PubMed Web of Science ®Google Scholar
• Lee P.I. Kinetics of drug release from hydrogel matrices. Journal of Controlled Release 1985; 2: 277–288
   Google Scholar
• Peppas N.A. Analysis of Fickian and non-Fickian drug release from polymers. Pharmaceutica Acta Helvetiae 1985; 60: 110–111
   PubMedGoogle Scholar
• Peppas N.A., Ségot-Chicq S. Les dispositifs à libération côntrolée pour la délivrance des principes actifs médicamenteux. III. Modélisation des mécanismes diffusionnels. Sciences Techniques et Pratiques Pharmaceutiques 1985; 1: 208–216
   Google Scholar
• Ratcliffe J.H., Hunneyball I.M., Smith A., Wilson C.G., Davis S.S. Preparation and evaluation of biodegradable polymeric systems for the intra-articular delivery of drugs. Journal of Pharmacy and Pharmacology 1984; 36: 431–436
   PubMed Web of Science ®Google Scholar
• Ritger P.L., Peppas N.A. A simple equation for description of solute release. I. Fickian and non-Fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs. Journal of Controlled Release 1987a; 5: 23–36
   Google Scholar
• Ritger P.L., Peppas N.A. A simple equation for description of solute release. II. Fickian and anomalous release from swellable devices. Journal of Controlled Release 1987b; 5: 37–42
   Google Scholar
• Robert C.C.R., Buri P.A., Peppas N.A. Influence of the drug solubility and dissolution medium on the release from poly(2-hydroxyethylmethacrylate) microspheres. Journal of Controlled Release 1987; 5: 151–157
   Google Scholar
• Swinyard E.A. Respiratory drugs. Remington's Pharmaceutical Sciences, 18th edn, A. R. Gennaro. Mack Publishing Co., Easton, PA 1990; 860–869
   Google Scholar
• Tanaka N., Takino S., Utsumi I. A new oral gelatinized sustained-release dosage form. Journal of Pharmaceutical Sciences 1963; 52: 664–667
   PubMed Web of Science ®Google Scholar
• Tomlinson E. Microsphere delivery systems for drug targeting and controlled release. International Journal of Pharmaceutical Technology and Product Manufacture 1983; 4(3)49–57
   Google Scholar
• White D.C. Simultaneous determination of sulphur and chlorine in organic compounds. Mikrochimica Acta 1962; 807–812
   Google Scholar