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Research Article

The Microsponge® Delivery System (MDS): a topical delivery system with reduced irritancy incorporating multiple triggering mechanisms for the release of actives

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Pages 575-588 | Received 13 Mar 1995, Accepted 20 Nov 1995, Published online: 27 Sep 2008

References

  • Eury R., Patel R., Longe K., Cheng T., Nacht S. Microsponge® delivery systems (MDS): A topical delivery system with multiple mechanism for triggering the release of actives. Cosmetic and Pharmaceutical Applications of Polymers. Plenum Press, New York 1991; 169–179
  • Franz T. J. Percutaneous absorption. On the relevance of in vitro data. J. Invest. Dermatol. 1975; 45: 498–503
  • Kydonieus A. F., Berner B. Transdermal Delivery of Drugs. CRC Press, Boca Raton 1987; Vol 1: 3–16
  • Nacht S. Efficacy of anti-acne drugs and formulations. Cosmetics & Toiletries 1986; 101: 47–55
  • Nacht S., Gans E. H., McGinley K. J. Comparative activity of benzoyl peroxide and hexachlorophene. In vivo studies against Propionibacterium acnes in humans. Arch. Dermatol. 1983; 119: 577–579
  • Nacht S., Katz M. The Microsponge®: A novel topical programmable delivery system. Topical Drug Delivery Formulations. Marcel Dekker, New York, NY 1990; 299–325
  • Wester R., Patel R., Nacht S., Leyden J., Melendres J., Maibach H. Controlled release of benzoyl peroxide from a porous microsphere polymeric system can reduce topical irritancy. J. Am. Acad. Derm. 1991; 24: 720–726
  • Williamson P., Kligman A. M. A new method for the quantitative investigation of cutaneous bacteria. J. Invest. Dermatol. 1965; 45: 498–503
  • Won R. U.S. Patent. No. 4,690,825, 1987, Method for delivering an active ingredient by controlled time release utilizing a novel delivery vehicle which can be prepared by a process utilizing the active ingredient as a porogen
  • Won R. U.S. Patent. No. 5,145,675, 1992, Two step method for preparation of controlled release formulations

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