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Research Article

Effect of gelation conditions and dissolution media on the release of paracetamol from alginate gel beads

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Pages 601-614 | Received 30 Mar 1995, Accepted 10 Sep 1995, Published online: 27 Sep 2008

References

  • Badwan A. A., Abumalooh A., Sallam E., Abukalaf A., Jawan P. A sustained release drug delivery system using calcium alginate beads. Drug Development and Industrial Pharmacy 1985; 11: 239–256
  • Cheetham P. S. J., Blunt K. W., Bucke C. Physical studies on cell immobilisation using calcium alginate gels. Biotechnology and Bioengineering 1979; 21: 2155–2168
  • Draget K. I., Skjak-Braek G., Smidsrod O. Alginic acid gels: the effect of alginate chemical composition and molecular weight. Carbohydrate Polymers 1994; 25: 31–38
  • Fernandex-Hervas M. J., Vela M. T., Holgado M. A., Del Cerro J., Rabasco A. M. Determination of percolation thresholds in matrix-type controlled release systems: applications of a resistance analysis technique. International Journal of Pharmaceutics 1995; 113: 39–45
  • Gray C. J., Dowsett J. Retention of insulin in alginate gel beads. Biotechnology and Bioengineering 1988; 31: 607–612
  • Kim C.-K., Lee E.-J. The controlled release of blue dextran from alginate beads. International Journal of Pharmaceutics 1992; 79: 11–19
  • Kupchik H. Z., Collins E. A., O'Brien M. J., McCaffrey R. P. Chemotherapy screening assay using 3-dimensional cell culture. Cancer Letters 1990; 51: 11–16
  • Kwok K. K., Groves M. J., Burgess D. J. Production of 5–15 micrometre diameter alginate-polylysine microcapsules by an air-atomisation technique. Pharmaceutical Research 1991; 8: 341–344
  • Lin S. Y., Ayres J. W. Calcium alginate beads as core carriers of 5-aminosalicylic acid. Pharmaceutical Research 1992; 9: 1128–1131
  • Maysinger D., Jalsenjak I., Cuello A. C. Microencapsulated nerve growth factors: effect on the forebrain neurons following devascularising cortical lesions. Neuroscience Letters 1992; 140: 71–74
  • McDowell R. H. Properties of alginates, 4th edition. Alginate Industries Ltd, London 1977
  • McNeely W. H., Pettitt D. J. Algin. Industrial Gums—Polysaccharides and their derivatives, R. L. Whistler. Academic Press, New York 1973; 49–81
  • Morris V. J. Gelation of polysaccharides. Functional Properties of Food Macro-molecules, J. R. Mitchell, D. A. Ledward. Elsevier Applied Science, New York 1986; 121–128
  • Mumper R. J., Hoffman A. S., Poulakkainen P. A., Bouchard L. S., Gombotz W. R. Calcium-alginate beads for the oral delivery of transforming growth factor-β1, (TGF-β1): stabilisation of TGF-β1, by the addition of polyacrylic acid within acid-treated beads. Journal of Controlled Release 1994; 30: 241–251
  • Ostberg T., Graffner C. Calcium alginate matrices for oral multiple unit administration: I. Pilot investigations of production method. Acta Pharmaceutica Nordica 1992; 4: 201–208
  • Ostberg T., Lund E. M., Graffner C. Calcium alginate matrices for oral multiple unit administration: IV. Release characteristics in different media. International Journal of Pharmaceutics 1994; 112: 241–248
  • Peppas N. A. Analysis of Frickian and non-Fickian drug release from polymers. Pharmaceutica Acta Helvitiae 1985; 60: 110–111
  • Peppas N. A., Sahlin J. J. A simple equation for the description of solute release. III. Coupling of diffusion and relaxation. International Journal of Pharmaceutics 1989; 57: 169–172
  • Rubio M. R., Ghaly E. S. In-vitro release of acetaminophen from sodium alginate controlled release pellets. Drug Development and Industrial Pharmacy 1994; 20: 1239–1251
  • Scherer P., Kluge M., Klein J., Sahm H. Immobilisation of the methanogenic bacterium Methanosarcina barkeri. Biotechnology and Bioengineering 1981; 23: 1057–1065
  • Smidsrod O., Skjak-Braek G. Alginate as immobilization matrix for cells. Trends in Biotechnology 1990; 8: 71–78

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