167
Views
54
CrossRef citations to date
0
Altmetric
Research Article

New strategies for the microencapsulation of tetanus vaccine

, , , &
Pages 299-318 | Received 10 Dec 1996, Accepted 14 Mar 1997, Published online: 27 Sep 2008

References

  • Aguado M. T., Lambert P. H. Controlled release vaccine-biodegradable polylactide/polyglycolide (PL/PG) microspheres as antigen vehicles. Immunobiology 1992; 184: 113–125
  • Alonso M. J., Gupta R. K., Min C., Siber G. R., Langer R. Microspheres as controlled-release tetanus toxoid delivery systems. Vaccine 1994; 12: 299–306
  • Alonso M. J., Villamayor B., Tobio M., Schwendeman S. P., Gupta R. K., Siber G., Langer R. Innovative approaches for the stabilization and controlled release of tetanus vaccine from polyester microspheres. Proceedings of the International Symposium on Controlled Release of Bioactive Materials 1996; 23: 825–826
  • Andrade J. D., Hlady V. Protein adsorption and materials biocompatibility: A tutorial review and suggested hypotheses. Advances in Polymer Science 1985; 79: 1–63
  • Burke P. A., Griffin R. G., Klibanov A. M. Solid-state NMR assessment of enzyme active center structure under nonaqueous conditions. Journal of Biological Chemistry 1992; 267: 20057–20064
  • Carpenter J. F., Prestrelski S. J., Arakawa T. Separation of freezing- and drying-induced denaturation of lyophilized proteins using stress-specific stabilization. Archives of Biochemistry &xs Biophysics 1993; 303: 456–464
  • Costantino H. R., Langer R., Klibanov A. M. Moisture-induced aggregation of lyophilized insulin. Pharmaceutical Research 1994a; 11: 21–29
  • Costantino H. R., Langer R., Klibanov A. M. Solid-phase aggregation of proteins under pharmaceutically relevant conditions. Journal of Pharmaceutical Sciences 1994b; 83: 1662–1669
  • Costrantino H. R., Langer R., Klibanov A. Aggregation of a lyophilized pharmaceutical protein, recombinant human albumin: Effect of moisture and stabilization by excipients. Bio/Technology 1995; 13: 493–496
  • Costantino H. R., Schwendeman S. P., Griebenow K., Klibanov A. M., Langer R. On the secondary structure and aggregation of lyophilized tetanus toxoid. Journal of Pharmaceutical Sciences 1996; 85: 1290–1293
  • Dabulis K., Klibanov A. M. Dramatic enhancement of enzymatic activity in organic solvents by lyoprotectants. Biotechnology and Bioengineering 1993; 41: 556–571
  • Gombotz W. R. Process for producing small particles of biologically active molecules. 1990, International Publication Number WO 90/13285
  • Greenspan L. Humidity fixed points of binary saturated aqueous solutions. Journal of Research, National Bureau of Standards 1977; 81A: 89–96
  • Gupta R. K., Siber G. R., Alonso M. J., Langer R. Development of a single-dose tetanus toxoid based on controlled release from biodegradable and biocompatible polyester microspheres. Vaccines 93, F. Brown, R. Chanock, H. Ginsberg, R. Lerner. Cold Spring Harbor Laboratory Press, Cold Spring Harbor 1993; 391–396
  • Hageman M. J. Water sorption and solid-state stability of proteins. Stability of Protein Pharmaceuticals. Part A. Chemical and Physical Pathways of Protein Degradation, T. J. Ahern, M. C. Manning. Plenum Press, New York 1992; 273–309
  • Herrlinger M. In vitro polymerabbau un wirksttofffreigabe von poly-DL-laktid-formlingen. University of Heildelberg. 1994, PhD Thesis
  • Hutchinson F. G., Furr B. J. A. Biodegradable polymer systems for the sustained release of polypeptides. Journal of Controlled Release 1990; 13: 279–294
  • Lee L., Lee J. Thermal stability of proteins in the presence of poly(ethylene glycols). Biochemistry 1990; 26: 7813–7819
  • Li S., Garreau H., Vert M. Structure-property relationships in the case of the degradation of massive aliphatic poly-(α-hydroxy acids) in aqueous media, Part 1: Poly(DL-lactic acid). Journal of Material Science, Muteria Medica 1990a; 1: 123–130
  • Li S. M., Garreau H., Vert M. Structure-property relationships in the case of the degradation of massive aliphatic poly-(α-hydroxy acids) in aqueous media, Part 2: Degradation of lactide-glycolide copolymers: PLA37.5GA25 and PLA75GA25. Journal of Material Science, Materia Medica 1990b; 1: 131–139
  • Liu W. R., Langer R., Klibanov A. M. Moisture-induccd aggregation of lyophilized proteins in the solid state. Biotechnology and Bioengineering 1991; 37: 177–184
  • Lusow A. R., Auado M. T., Dei Guidici G., Lambert P. H. Towards vaccine optimization. Immunology Letters 1990; 25: 255
  • Masood H., White J. L., Hem S. L. Relationship between protein adsorptive capacity and the X-ray diffraction pattern of aluminium hydroxide adjuvants. Vaccine 1994; 12: 187–189
  • Ogawa Y., Okada H., Heya T., Shimamoto T. Controlled release of LHRH agonist, Ieuprohde acetate, from microcapsules: serum drug level profiles and phaniacological effects in animals. Journal of Pharmacy and Phamacology 1989; 41: 439–444
  • Ogawa Y., Okada H., Yamamoto M., Shimamoto T. In vivo release profiles of leuprolide acetate from microcapsules prepared with polylactic acids or copoly(lactic/glycolic acids) and in vivo degradation of these polymers. Chemical and Pharmaceutical Bulletin 1988a; 36: 2576–2581
  • Ogawa Y., Yamamoto M., Okada H., Yashiki T., Shimamoto T. A new technique to effciently entrap leuprolide acetate into microcapsules of polylactic acid or copoly(lactic/glycolic) acid. Chemical and Pharmaceutical Bulletin 1988b; 36: 1095–1103
  • Ogawa Y., Yamamoto M., Takada S., Okada H., Shimamoto T. Controlled-release of leuprolide acetate from polylactic acid or copoly(lactic/glycolid) acid microcapsules: Influence of molecular weight and copolymer ratio of polymer. Chemical and Pharmaceutical Bulletin 1988c; 36: 1502–1507
  • Okada H., Heya H., Ogama Y., Shimamoto T. One-month release injectable microcapsules of a luteinizing hormone-releasing hormone agonist (leuprolide acetate) for treating experimental endometriosis in. rats. Journal of Pharmacology and Experimental Therapeutics 1988; 244: 744–750
  • Okada H., Inoue Y., Heya T., Ueno H., Ogawa Y., Toguchi H. Pharmacokinetics of once-a-month injectable microspheres of leuprolide acetate. Pharmaceutical Research 1991; 8: 787–791
  • Schein C. H. Solubility as a function of protein structure and solvent components. Bio/technology 1990; 8: 308–317
  • Schwendeman S. P., Cardamone M., Brandon M. R., Klibanov A., Lancer R. Stability of proteins and thcir delivery from biodegradable polymer microspheres. Microparticulate Systems for the Delivery of Proteins and Vaccines, S. Cohen, H. Bertstein. Marcel Dekker, New York 1995a; 1–49
  • Schwendeman S. P., Costantino H. R., Gupta R. K., Siber G. R., Klibanov A. M., Langer R. Stabilization of tetanus and diphtheria toxoids against moisture-induced aggregation. Proceedings of the National Academy of Sciences, USA 1995b; 92: 11234–11238
  • Schwendeman S. P., Costantino H. R., Gupta R. K., Tobio M., Chang A.-C., Alonso M. J., Siber G. R., Langer R. Strategies for the stabilization of tetanus toxoid toward the development of a single-dose tetanus vaccine. Developments in Biological Standardization 1996; 87: 293–306
  • Schwendeman S. P., Gupta R. K., Siber G. R., Langer R. Pathways of inactivation of tetanus toxoid in the presence of PLA 2000. Pharmaceutical Research 1995c; 12: S80
  • Schwendeman S. P., Lee J. H., Gupta R. K., Costantino H. R., Siber G. R., Langer R. Inhibition of moisture-induced aggregation of tetanus toxoid by protecting thiol groups. Proceedings of the International Symposium on Controlled Release of Bioactive Materials 1994; 21: 54–55
  • Sluzky V., Klibanov A. M., Langer R. Mechanism of insulin aggregation and stabilization in agitated aqueous solutions. Biotechnology and Bioengineering 1992; 40: 895–903
  • Sluzky V., Tamada J. A., Klibanov A. M., Langer R. Kinetics of insulin aggregation in aqueous solutions upon agitation in the presence of hydrophobic surfaces. Proreedings of the National Academy of Sciences, USA 1991; 88: 9377–9381
  • Toguchi H. Pharmaceutical manipulation of leuprolide acetate to improve clinical performance. Journal of International Medical Research 1990; 18(suppl. 1)35–41
  • Volkin D. B., Klibanov A. M. Minimizing protein inactivation. Protein Function: A Practical Approach, T. E. Creighton. Oxford University Press, Oxford 1989; 1–24
  • Vrkljan M., Foster T., Powers M., Henkin J., Porter W., Staack H., Carpenter J., Manning M. Thermal stability of low molecular weight urokinase during heat treatment. II. Effect of polymer additives. Pharmaceutical Research 1994; 11: 1004–1008
  • Wada R., Hyon S. H., Ykada Y. Lactic acid oligomer microspheres containing hydrophilic drug. Journal of Pharmaceutical Sciences 1990; 78: 919–924
  • WHO. Meeting of the Working Group on Single-dose Tetanus Vaccines (World Health Organization Global Programme for Vaccines and Immunization). The Food and Drug Administration, Bethesda, MD 1995
  • Youngs J. F. Humidity control in the laboratory using salt solutions—a review. Journal of Applied Chemistry 1967; 17: 241–245
  • Zaks A., Klibanov A. M. The effect of water on enzyme action in organic media. Journal of Biological Chemistry 1988; 263: 8017–8021

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.