Effects of hyperthermia on Hsp27 (HSPB1), Hsp72 (HSPA1A) and DNA repair proteins hMLH1 and hMSH2 in human colorectal cancer hMLH1-deficient and hMLH1-proficient cell lines

References

• Hurwitz MD. Today's thermal therapy: Not your father's hyperthermia: Challenges and opportunities in application of hyperthermia for the 21st century cancer patient. Am J Clin Oncol 2011; 33: 96–100
   Web of Science ®Google Scholar
• Walther W, Stein U. Heat-responsive gene expression for gene therapy. Adv Drug Deliv Rev 2009; 61: 641–649
   PubMed Web of Science ®Google Scholar
• Kampinga HH, Hageman J, Vos MJ, Kubota H, Tanguay RM, Bruford EA, et al. Guidelines for the nomenclature of the human heat shock proteins. Cell Stress Chaperones 2009; 14: 105–111
   PubMed Web of Science ®Google Scholar
• Ciocca DR, Calderwood SK. Heat shock proteins in cancer: Diagnostic, prognostic, predictive and treatment implications. Cell Stress Chaperones 2005; 10: 86–103
   PubMed Web of Science ®Google Scholar
• Roti Roti JL. Heat-induced alterations of nuclear protein associations and their effects on DNA repair and replication. Int J Hyperthermia 2007; 23: 3–15
   PubMed Web of Science ®Google Scholar
• Vanderwaal RP, Roti Roti JL. Heat induced ‘masking’ of redox sensitive component(s) of the DNA-nuclear matrix anchoring complex. Int J Hyperthermia 2004; 20: 234–239
   PubMed Web of Science ®Google Scholar
• Roti Roti JL. Cellular responses to hyperthermia (40–46°C): Cell killing and molecular events. Int J Hypertthermia 2008; 24: 3–15
   PubMed Web of Science ®Google Scholar
• Takahashi A, Matsumoto H, Nagayama K, Kitano M, Hirose S, Tanaka H, et al. Evidence for the involvement of double-strand breaks in heat-induced cell killing. Cancer Res 2004; 64: 8839–8845
   PubMed Web of Science ®Google Scholar
• Takahashi A, Yamakawa N, Mori E, Ohnishi K, Yokota S, Sugo N, et al. Development of thermotolerance requires interaction between polymerase-beta and heat shock proteins. Cancer Sci 2008; 99: 973–978
   PubMed Web of Science ®Google Scholar
• Nadin SB, Ciocca DR. Participation of heat shock proteins in DNA repair mechanisms in cancer. DNA Repair: Damage, Repair Mechanisms and Aging, F Columbus. Nova Science Publishers, New York 2010; 165–186
   Google Scholar
• Kotoglou P, Kalitzakis A, Vezyraki P, Tzavaras T, Michalis LK, Dantzar F, et al. Hsp70 translocates to the nuclei and nucleoli, binds to XRCC1 and PARP-1, and protects HeLa cells from single-strand DNA breaks. Cell Stress Chaperones 2009; 14: 391–406
   PubMed Web of Science ®Google Scholar
• Hunt CR, Dix DJ, Sharma GG, Pandita RK, Gupta A, Funk M, et al. Genomic instability and enhanced radiosensitivity in Hsp70.1- and Hsp70.3-deficient mice. Mol Cell Biol 2004; 24: 899–911
   PubMed Web of Science ®Google Scholar
• Peltomaki P. Role of DNA mismatch repair defects in the pathogenesis of human cancer. J Clin Oncol 2003; 21: 1174–1179
   PubMed Web of Science ®Google Scholar
• Jiricny J. Mismatch repair: The praying hands of fidelity. Curr Biol 2000; 10: 788–790
   Web of Science ®Google Scholar
• Hoeijmakers JHJ. Genomic maintenance mechanisms for preventing cancer. Nature 2001; 411: 366–374
   PubMed Web of Science ®Google Scholar
• Li G-M. Mechanisms and functions of DNA mismatch repair. Cell Res 2008; 18: 85–98
   PubMed Web of Science ®Google Scholar
• Nadin SB, Vargas-Roig LM, Drago G, Ibarra J, Ciocca DR. Hsp27, Hsp70 and mismatch repair proteins hMLH1 and hMSH2 expression in peripheral blood lymphocytes from healthy subjects and cancer patients. Cancer Lett 2007; 252: 131–146
   PubMed Web of Science ®Google Scholar
• Bronner CE, Baker SM, Morrison PT, Warren G, Smith LG, Lescoe MK, et al. Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer. Nature 1994; 368: 258–261
   PubMed Web of Science ®Google Scholar
• Boyer JC, Umar A, Risinger JI, Lipford JR, Kane M, Yin S, et al. Microsatellite instability, mismatch repair deficiency, and genetic defects in human cancer cell lines. Cancer Res 1995; 55: 6063–6070
   PubMed Web of Science ®Google Scholar
• Koi M, Umar A, Chauhan DP, Cherian SP, Carethers JM, Kunkel TA, et al. Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N’-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation. Cancer Res 1994; 54: 4308–4312
   PubMed Web of Science ®Google Scholar
• Andrews NC, Faller DV. A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucleic Acids Res 1991; 19: 2499
   PubMed Web of Science ®Google Scholar
• Olive PL, Wlodek D, Durand RE, Banáth JP. Factors influencing DNA migration from individual cells subjected to gel electrophoresis. Exp Cell Res 1992; 198: 259–267
   PubMed Web of Science ®Google Scholar
• Nadin SB, Vargas-Roig LM, Ciocca DR. A silver staining method for single-cell gel assay. J Histochem Cytochem 2001; 49: 1183–1186
   PubMed Web of Science ®Google Scholar
• Anderson D, Yu T-W, Phillips BJ, Shemezer P. The effect of various antioxidants and other modifying agents on oxygen-radical-generated DNA damage in human lymphocytes in the COMET assay. Mutat Res 1994; 307: 261–271
   PubMed Web of Science ®Google Scholar
• Branham MT, Nadin SB, Vargas-Roig LM, Ciocca DR. DNA damage induced by paclitaxel and DNA repair capability of peripheral blood lymphocytes as evaluated by the alkaline comet assay. Mutat Res 2004; 560: 11–17
   PubMed Web of Science ®Google Scholar
• Schemezer P, Rajaee-Behbahani N, Risch A, Thiel S, Rittgen W, Drings P, et al. Rapid screening assay for mutagen sensitivity and DNA repair capacity in human peripheral blood lymphocytes. Mutagenesis 2001; 16: 25–30
   PubMed Web of Science ®Google Scholar
• Yaglom JA, Gabai VL, Sherman MY. High levels of heat shock protein Hsp72 in cancer cells suppress default senescence pathways. Cancer Res 2007; 67: 2373–2381
   PubMed Web of Science ®Google Scholar
• Chughtai ZS, Rassadi R, Matusiewicz N, Stochaj U. Starvation promotes nuclear accumulation of the Hsp70 Ssa4p in yeast cells. J Biol Chem 2001; 276: 20261–20266
   PubMed Web of Science ®Google Scholar
• Lepock JR, Frey HE, Heynen ML, Senisterra GA, Warters RL. The nuclear matrix is a thermolabile cellular structure. Cell Stress Chaperones 2001; 6: 136–147
   PubMed Web of Science ®Google Scholar
• Szekely L, Jiang WQ, Pokrovskaja K, Wiman KG, Klein G, Ringertz N. Reversible nucleolar translocation of Epstein-Barr virus-encoded EBNA-5 and Hsp70 proteins after exposure to heat shock or cell density congestion. J Gen Virol 1995; 76: 2423–2432
   PubMed Web of Science ®Google Scholar
• Calini V, Urani C, Camatini M. Overexpression of Hsp70 is induced by ionizing radiation in C3H 10T1/2 cells and protects from DNA damage. Toxicol In Vitro 2003; 17: 561–566
   PubMed Web of Science ®Google Scholar
• Niu P, Liu L, Gong Z, Tan H, Wang F, Yuan J, et al. Overexpressed heat shock protein 70 protects cells against DNA damage caused by ultraviolet C in a dose-dependent manner. Cell Stress Chaperones 2006; 11: 162–169
   PubMed Web of Science ®Google Scholar
• Mendez F, Kozin E, Bases R. Heat shock protein 70 stimulation of the deoxyribonucleic acid base excision repair enzyme polymerase beta. Cell Stress Chaperones 2003; 8: 153–161
   PubMed Web of Science ®Google Scholar
• Zhu WG, Seno JD, Beck BD, Dynlacht JR. Translocation of MRE11 from the nucleus to the cytoplasm as a mechanism of radiosensitization by heat. Radiat Res 2001; 156: 95–102
   PubMed Web of Science ®Google Scholar
• Xu M, Myerson RJ, Xia Y, Whitehead T, Moros EG, Straube WL, et al. The effects of 41°C hyperthermia on the DNA repair protein, MRE11, correlate with radiosensitization in four human tumour cell lines. Int J Hyperthermia 2007; 23: 343–351
   PubMed Web of Science ®Google Scholar
• Dynlacht JR, Xu M, Pandita RK, Wetzel EA, Roti Roti JL. Effects of heat shock on the Mre11/Rad50/Nbs1 complex in irradiated or unirradiated cells. Int J Hyperthermia 2004; 20: 144–156
   PubMed Web of Science ®Google Scholar
• Pabla N, Ma Z, McIlhatton MA, Fishel R, Dong Z. hMSH2 recruits ATR to DNA damage sites for activation during DNA damage-induced apoptosis. J Biol Chem 2011; 286: 10411–10418
   Google Scholar
• Brieger A, Adam R, Passmann S, Plotz G, Zeuzem S, Trojan J. A CRM1-dependent nuclear export pathway is involved in the regulation of MutLα subcellular localization. Genes Chromosomes Cancer 2011; 50: 59–70
   PubMed Web of Science ®Google Scholar
• Mastrocola AS, Heinen CD. Nuclear reorganization of DNA mismatch repair proteins in response to DNA damage. DNA Repair (Amst) 2010; 9: 120–133
   PubMed Web of Science ®Google Scholar
• Laszlo A. The effects of hyperthermia on mammalian cell structure and function. Cell Prolif 1992; 25: 59–87
   PubMed Web of Science ®Google Scholar
• Kampinga HH, Dynlacht JR, Dikomey E. Mechanism of radiosensitization by hyperthermia (> or = 43°C) as derived from studies with DNA repair defective mutant cell lines. Int J Hyperthermia 2004; 20: 131–139
   PubMed Web of Science ®Google Scholar
• Bruskov VI, Malakhova LV, Masalimov ZK, Chernikov AV. Heat-induced formation of reactive oxygen species and 8-oxoguanine, a biomarker of damage to DNA. Nucleic Acids Res 2002; 30: 1354–1363
   PubMed Web of Science ®Google Scholar
• Warters RL, Brizgys LM. Apurinic site induction in the DNA of cells heated at hyperthermic temperatures. J Cell Physiol 1987; 133: 144–150
   PubMed Web of Science ®Google Scholar
• Lindahl T, Nyberg B. Heat-induced deamination of cytosine residues in deoxyribonucleic acid. Biochemistry 1974; 13: 3405–3410
   PubMed Web of Science ®Google Scholar
• Hall DM, Buettner GR, Matthes RD, Gisolfi CV. Hyperthermia stimulates nitric oxide formation: Electron paramagnetic resonance detection of NO-heme in blood. J Appl Physiol 1994; 77: 548–553
   PubMed Web of Science ®Google Scholar
• McKelvey-Martin VJ, Green MHL, Schemezer P, Pool-Zobel BL, De Méo MP, Collins A. The single cell gel electrophoresis assay (comet assay): A European review. Mutat Res 1993; 288: 47–63
   PubMed Web of Science ®Google Scholar
• Lin X, Ramamurthi K, Mishima M, Kondo A, Christen RD, Howell SB. p53 modulates the effect of loss of DNA mismatch repair on the sensitivity of human colon cancer cells to the cytotoxic and mutagenic effects of cisplatin. Cancer Res 2001; 61: 1508–1516
   PubMed Web of Science ®Google Scholar
• Hunt CR, Pandita RK, Laszlo A, Higashikubo R, Agarwal M, Kitamura T, et al. Hyperthermia activates a subset of ataxia-telangiectasia mutated effectors independent of DNA strand breaks and heat shock protein 70 status. Cancer Res 2007; 67: 3010–3017
   PubMed Web of Science ®Google Scholar
• Kampinga HH, Laszlo A. DNA double strand breaks do not play a role in heat-induced cell killing. Cancer Res 2005; 65: 10632–10633
   PubMed Web of Science ®Google Scholar
• Laszlo A, Fleischer I. The heat-induced gamma-H2AX response does not play a role in hyperthermic cell killing. Int J Hyperthermia 2009; 25: 199–209
   PubMed Web of Science ®Google Scholar
• Vanderwaal RP, Maggi LB, Jr, Weber JD, Hunt CR, Roti Roti JL. Nucleophosmin redistribution following heat shock: A role in heat-induced radiosensitization. Cancer Res 2009; 69: 6454–6462
   PubMed Web of Science ®Google Scholar
• Roti Roti JL, Pandita RK, Mueller JD, Novak P, Moros EG, Laszlo A. Severe, short-duration (0–3 min) heat shocks (50–52°C) inhibit the repair of DNA damage. Int J Hyperthermia 2010; 26: 67–78
   PubMed Web of Science ®Google Scholar