Whole body hyperthermia treatment increases interleukin 10 and toll-like receptor 4 expression in patients with ankylosing spondylitis: A pilot study

References

• Braun J, van den Berg R, Baraliakos X, Boehm H, Burgos-Vargas R, Collantes-Estevez E, et al. 2010 update of the ASAS/EULAR recommendations for the management of ankylosing spondylitis. Ann Rheum Dis 2011;70:896–904
   PubMed Web of Science ®Google Scholar
• Dagfinrud H, Kvien TK, Hagen KB. Physiotherapy interventions for ankylosing spondylitis. Cochrane Database Syst Rev 2008;23:CD002822
   Google Scholar
• Falkenbach A, Kovacs J, Franke A, Jörgens K, Ammer K. Radon therapy for the treatment of rheumatic diseases − Review and meta-analysis of controlled clinical trials. Rheumatol Int 2005;25:205–10
   PubMed Web of Science ®Google Scholar
• Van Tubergen A, Landewe R, van der Heijde D, Hidding A, Wolter N, Asscher M, et al. Combined spa–exercise therapy is effective in patients with ankylosing spondylitis: A randomized controlled trial. Arthritis Rheum 2001;45:430–38
   PubMed Web of Science ®Google Scholar
• Bal A, Unlu E, Bahar G, Aydog E, Eksioglu E, Yorgancioglu R. Comparison of serum IL-1 beta, sIL-2R, IL-6, and TNF-alpha levels with disease activity parameters in ankylosing spondylitis. Clin Rheumatol 2007;26:211–15
   PubMed Web of Science ®Google Scholar
• Ostberg JR, Taylor SL, Baumann H, Repasky EA. Regulatory effects of fever-range whole-body hyperthermia on the LPS-induced acute inflammatory response. J Leukoc Biol 2000;68:815–20
   PubMed Web of Science ®Google Scholar
• Fairchild KD, Viscardi RM, Hester L, Singh IS, Hasday JD. Effects of hypothermia and hyperthermia on cytokine production by cultured human mononuclear phagocytes from adults and newborns. J Interferon Cytokine Res 2000;20:1049–55
   PubMed Web of Science ®Google Scholar
• Katschinski DM, Wiedemann GJ, Longo W, d’Oleire FR, Spriggs D, Robins HI. Whole body hyperthermia cytokine induction: A review, and unifying hypothesis for myeloprotection in the setting of cytotoxic therapy. Cytokine Growth Factor Rev 1999;10:93–7
   PubMed Web of Science ®Google Scholar
• Matsui T, Kakeda T. IL-10 production is reduced by hypothermia but augmented by hyperthermia in rat microglia. J Neurotrauma 2008;25:709–15
   PubMed Web of Science ®Google Scholar
• Bouchama A, al-Sedairy S, Siddiqui S, Shail E, Rezeig M. Elevated pyrogenic cytokines in heatstroke. Chest 1993;104:1498–502
   PubMed Web of Science ®Google Scholar
• Robins HI, Kutz M, Wiedemann GJ, Katschinski DM, Paul D, Grosen E, et al. Cytokine induction by 41.8 °C whole body hyperthermia. Cancer Lett 1995;97:195–201
   PubMed Web of Science ®Google Scholar
• Dieing A, Ahlers O, Hildebrandt B, Kerner T, Tamm I, Possinger K, et al. The effect of induced hyperthermia on the immune system. Prog Brain Res 2007;162:137–52
   PubMed Web of Science ®Google Scholar
• Tomiyama-Miyaji C, Watanabe M, Ohishi T, Kanda Y, Kainuma E, Bakir HY, et al. Modulation of the endocrine and immune systems by well-controlled hyperthermia equipment. Biomed Res 2007;28:119–25
   PubMed Web of Science ®Google Scholar
• Appenheimer MM, Chen Q, Girard RA, Wang WC, Evans SS. Impact of fever-range thermal stress on lymphocyte–endothelial adhesion and lymphocyte trafficking. Immunol Invest 2005;34:295–323
   PubMed Web of Science ®Google Scholar
• Kappel M, Diamant M, Hansen MB, Klokker M, Pedersen BK. Effects of in vitro hyperthermia on the proliferative response of blood mononuclear cell subsets, and detection of interleukins 1 and 6, tumour necrosis factor-alpha and interferon-gamma. Immunology 1991;73:304–8
   PubMed Web of Science ®Google Scholar
• Downing JF, Martinez-Valdez H, Elizondo RS, Walker EB, Taylor MW. Hyperthermia in humans enhances interferon-gamma synthesis and alters the peripheral lymphocyte population. J Interferon Res 1988;8:143–50
   PubMedGoogle Scholar
• Ostberg JR, Kabingu E, Repasky EA. Thermal regulation of dendritic cell activation and migration from skin explants. Int J Hyperthermia 2003;19:520–33
   PubMed Web of Science ®Google Scholar
• Peng JC, Hyde C, Pai S, O’Sullivan BJ, Nielsen LK, Thomas R. Monocyte-derived DC primed with TLR agonists secrete IL-12p70 in a CD40-dependent manner under hyperthermic conditions. J Immunother 2006;29:606–15
   PubMed Web of Science ®Google Scholar
• Bannikov AV, Dorofeikov VV, Freidlin TS, Freidlin IS, Shustov EB, Shcherbak IG, et al. Characteristics of the acute phase reaction in humans with various types of autonomic nervous system regulation during simulated hyperthermia. Ross Fiziol Zh Im I M Sechenova 2000;86:41–5
   PubMedGoogle Scholar
• Hietala J, Nurmi T, Uhari M, Pakarinen A, Kouvalainen K. Acute phase proteins, humoral and cell mediated immunity in environmentally-induced hyperthermia in man. Eur J Appl Physiol Occup Physiol 1982;49:271–6
   PubMed Web of Science ®Google Scholar
• Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A, et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 2002;18:7
   Google Scholar
• Brunner E, Puri ML. Nonparametric methods in factorial designs. Stat Pap 2001;42:1–52
   Web of Science ®Google Scholar
• Benjamini Y, Hochberg Y. On the adaptive control of the false discovery rate in multiple testing with independent statistics. J Educ Behav Stat 2000;25:60–83
   Web of Science ®Google Scholar
• Hwang YT, Chu SK, Ou ST. Evaluations of FDR-controlling procedures in multiple hypothesis testing. Stat Comput 2011;21:569–83 www.rproject.org
   Google Scholar
• The R project for statistical computing. http://www.r-project.org/ (accessed 2 May 2013)
   Google Scholar
• Kraybill WG, Olenki T, Evans SS, Ostberg JR, O’Leary KA, Gibbs JF, et al. A phase I study of fever-range whole body hyperthermia (FR-WBH) in patients with advanced solid tumours: Correlation with mouse models. Int J Hyperthermia 2002;18:253–66
   PubMed Web of Science ®Google Scholar
• Peer AJ, Grimm MJ, Zynda ER, Repasky EA. Diverse immune mechanisms may contribute to the survival benefit seen in cancer patients receiving hyperthermia. Immunol Res 2010;46:137–54
   PubMed Web of Science ®Google Scholar
• Zellner M, Hergovics N, Roth E, Jilma B, Spittler A, Oehler R. Human monocyte stimulation by experimental whole body hyperthermia. Wien Klin Wochenschr 2002;114:102–7
   PubMed Web of Science ®Google Scholar
• Milani V, Noessner E, Ghose S, Kuppner M, Ahrens B, Scharner A, et al. Heat shock protein 70: role in antigen presentation and immune stimulation. Int J Hyperthermia 2002;18:563–85
   PubMed Web of Science ®Google Scholar
• Asea A, Kraeft SK, Kurt-Jones EA, Stevenson MA, Chen LB, Finberg RW. Hsp70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine. Nat Med 2000;6:435–42
   PubMed Web of Science ®Google Scholar
• Pockley AG. Heat shock proteins are regulators of the immune response. Lancet 2003;362(9382):469–76
   PubMed Web of Science ®Google Scholar
• Singh IS, Hasday JD. Fever, hyperthermia and the heat shock response. Int J Hyperthermia 2013;29:423–35
   PubMed Web of Science ®Google Scholar
• Yan X, Xiu F, An H, Wang X, Wang J, Cao X. Fever range temperature promotes TLR4 expression and signaling in dendritic cells. Life Sci 2007;80:307–13
   PubMed Web of Science ®Google Scholar
• Zhao W, An H, Zhou J, Xu H, Yu Y, Cao X. Hyperthermia differentially regulates TLR4 and TLR2-mediated innate immune response. Immunol Lett 2007;108:137–42
   PubMed Web of Science ®Google Scholar
• Ahlers O, Hildebrandt B, Dieing A, Deja M, Bohnke T, Wust P, et al. Stress induced changes in lymphocyte subpopulations and associated cytokines during whole body hyperthermia of 41.8−42.2 °C. Eur J Appl Physiol 2005;95:298–306
   PubMed Web of Science ®Google Scholar
• Tarner IH, Muller-Ladner U, Uhlemann C, Lange U. The effect of mild whole-body hyperthermia on systemic levels of TNF-alpha, IL-1beta, and IL-6 in patients with ankylosing spondylitis. Clin Rheumatol 2009;28:397–402
   PubMed Web of Science ®Google Scholar