12
Views
11
CrossRef citations to date
0
Altmetric
Original Article

Potentiation of melphalan by systemic hyperthermia in mice: Therapeutic gain for mouse lung microtumours

&
Pages 57-68 | Received 24 Oct 1984, Published online: 09 Jul 2009

References

  • Bicher H. I., Hetzel F. W., Sandhu T. S., Frinak S., Vaupel P., O'Hara M. D., O'Brien T. Effects of hyperthermia on normal and tumour microenvironment. Radiology 1980; 137: 523–530
  • Brown J. M., Parker E. T. Host treatments affecting artificial pulmonary metastases: interpretation of loss of radioactivity labelled cells from lungs. British Journal of Cancer 1979; 40: 677–688
  • Brown J. M., Twentyman P. R., Zamvil S. S. Response of the RIF-1 tumour in vitro and in C3H/Km mice to X-radiation (Cell survival, regrowth delay, and tumour control), chemotherapeutic agents, and activated macrophages. Journal of the National Cancer Institute 1980; 64: 605–611
  • Dfwhirst M. W., Sim D. A., Gross J., Kundrat M. A. Effect of heating rate on tumour and normal tissue microcirculatory function. Hyperthermic Oncology 1984, J. Overgaard. Taylor and Francis, London, Philadelphia 1984; Vol. 1: 177–180, Summary Papers
  • Dorie M. J., Kallman R. F. Reoxygenation in the RIF-1 tumour. International Journal of Radiation Oncology, Biology, Physics 1984; 10: 687–693
  • Dudar T. E., Jain R. K. Differential response of normal and tumour microcirculation to hyperthermia. Cancer Research 1984; 44: 605–612
  • Hahn G. M., Shiu E. C. Effect of pH and elevated temperatures on the cytoxicity of some chemotherapeutic agents on Chinese hamster cells in vitro. Cancer Research 1983; 43: 5789–5791
  • Hill R. P., Bush R. S. A lung-colony assay to determine the radiosensitivity of the cells of a solid tumour. International Journal of Radiation Biology 1969; 5: 435–444
  • Hill R. P., Bush R. S. A new method of determining the fraction of hypoxic cells in a transplantable murine sarcoma. Radiation Research 1977; 70: 141–153
  • Honess D. J., Bleehen N. M. Sensitivity of normal mouse marrow and RIF-1 tumour to hyperthermia combined with cyclophosphamide or BCNU: a lack of therapeutic gain. British Journal of Cancer 1982; 46: 236–248
  • Honess D. J., Bleehen N. M. Thermochemotherapy with cis-platinum, CCNU, BCNU, chlorambucil and melphalan on murine marrow and 2 tumours: therapeutic gain for melphalan only. British Journal of Radiology 1985; 58: 63–72
  • Honlss D. J., Donaldson J., Workman P., Bleehen N. M. The effect of systemic hyperthermia on melphalan pharmacokinetics in mice. British Journal of Cancer 1985; 51: 77–84
  • Kali man R. F., De Nardo G. L., Stasch M. J. Blood flow in irradiated mouse sarcoma as determined by the clearance of Xenon-133. Cancer Research 1972; 32: 483–490
  • Kallman R. F., Silini G., Van Putten L. M. Factors influencing the quantitative estimation of the in vivo survival of cells from solid tumours. Journal of the National Cancer Institute 1967; 39: 539–549
  • Moulder J. E., Rockwell S. Hypoxic fractions of solid tumours: experimental techniques, methods of analysis, and a survey of existing data. International Journal of Radiation Oncology, Biology, Physics 1984; 10: 695–712
  • Parsons P. Dependence on treatment time of melphalan resistance and DNA cross-linking in human melanoma cell lines. Cancer Research 1984; 44: 2773–2778
  • Reeve J. R., Twentyman P. R. Clonal variation in the arrest, survival and growth of RIF-1 mouse sarcoma cells in the lungs of C3H mice. British Journal of Cancer 1983; 47: 833–840
  • Sapirstein L. A. Regional blood flow by fractional distribution of indicators. American Journal of Physiology 1958; 193: 161–168
  • Siemann D. W., Lord E. M., Keng P. C., Wheeler K. T. Cell sub-populations dispersed from solid tumours and separated by centrifugal elutriation. British Journal of Cancer 1981; 44: 100–108
  • Song C. W. Physiological factors in hyperthermia of tumours. Physical aspects of hyperthermia, G. Nussbaum. American Institute of Physics, New York 1982; 43–62
  • Twentyman P. R., Brown J. M., Gray J. W., Franko A. J., Scoles M. A., Kallman R. F. A new mouse model tumour system (RIF-1) for comparison of end-point studies. Journal of the National Cancer Institute 1980; 64: 595–604
  • Twentyman P. R., Yuhas J. M. Use of bacterial neutral protease for disaggregation of mouse tumours and multicellular tumour spheroids. Cancer Letters 1980; 9: 225–228

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.