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International Journal of Hyperthermia Volume 4, 1988 - Issue 5
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Original Article

Sensitivities of bleomycin-resistant variant cells enhanced by 40°C hyperthermia in vitro

Eiichi Kano Department of Experimental Radiology and Health physics, Fukui Medical University, Matsuoka, Fukui, 910-11, Japan
,
Masayo Furukawa-furuya Department of Experimental Radiology and Health physics, Fukui Medical University, Matsuoka, Fukui, 910-11, Japan
,
Kazumi Nitta Department of Experimental Radiology and Health physics, Fukui Medical University, Matsuoka, Fukui, 910-11, Japan
,
Tomoko Kajimoto-kinoshita Department of Radiation Biology, Kyoto College of Pharmacy, Yamashina, Kyoto, 607, Japan
,
Porntipa Picha Research Division, National Cancer Institute, Bangkok, 10400, Thailand
,
Kiyoshi Sugimoto Department of Radiology, Osaka City, University School of Medicine, Abeno, Osaka, 545, Japan
,
Toshio Ohtsubo Department of Experimental Radiology and Health physics, Fukui Medical University, Matsuoka, Fukui, 910-11, Japan
,
Koh Tsuji Department of Experimental Radiology and Health physics, Fukui Medical University, Matsuoka, Fukui, 910-11, Japan
,
Susumu Tsubouchi Department of Experimental Radiology and Health physics, Fukui Medical University, Matsuoka, Fukui, 910-11, Japan
&
Takashi Kondo Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20892, USA
 show all
Pages 547-553 | Received 08 Jul 1987, Published online: 09 Jul 2009

References

  • Dahl O., Mella O. Enhanced effect of combined hyperthermia and chemotherapy (bleomycin, BCNU) in a neurogenetic rat tumor (BT4A) in vivo. Anticancer Research 1982; 2: 359–364
  • Hahn G. M. Thermal enhancement of the actions of anticancer agents. Hyperthermia and Cancer, G. M. Hahn. Plenum, New York 1982; 55–86
  • Hahn G. M., Strande D. P. Cytotoxic effects of hyperthermia and adriamycin on Chinese hamster cells. Journal of the National Cancer Institute 1976; 57: 1063–1067
  • Hahn G. M., Braun J., Har-Kedar I. Thermochemotherapy: synergism between hyperthermia (42-43°C) and adriamycin (or bleomycin) in mammalian cell inactivation. Proceedings of the National Academy of Sciences, U.S.A. 1975; 72: 937–940
  • Henle K. J., Leeper D. B. Modification of the heat response and thermotolerance by cycloheximide, hydroxyurea and lucanthone in CHO cells. Radiation Research 1982; 90: 339–347
  • Kano E., Miyakoshi J., Sugahara T. Difference in sensitivities to hyperthermia and ionizing radiation of various mammalian cell strains in vitro. Cancer Therapy by Hyperthermia and Radiation, C. Streffer, et al. Urban and Schwarzenberg, Baltimore, Munich 1978; 188–190
  • Nakajima K., Hisazumi H. An experimental study of enhanced cell killing by hyperthermia and bleomycin. Urology Research 1983; 11: 43–46
  • Suzuki K. Application of heat to cancer chemotherapy: Experimental studies. Nagoya Journal of Medical Science 1967; 30: 1–21
  • Terasima T., Umezawa H. Lethal effect of bleomycin on cultured mammalian cells. Journal of Antibiotics 1970; 23: 300–304
  • Terasima T., Umezawa H. Effect of bleomycin on mammalian cell survival. Journal of the National Cancer Institute 1972; 49: 1093–1100

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