6
Views
8
CrossRef citations to date
0
Altmetric
Original Article

Effects of adriamycin and hyperthermia on cellular uptake of [3H]thymidine and its significance for the incorporation into DNA

, , , , &
Pages 329-340 | Received 11 Feb 1988, Accepted 20 Jun 1988, Published online: 09 Jul 2009

References

  • Barranco S. C., Gerner E. W., Burk K. H., Humphrey R. M. Survival and cell kinetics effects of adriamycin on mammalian cells. Cancer Research 1973; 33: 11–16
  • Bhuyan B. K., Blowers C. L., Shugars K. D. Lethality of nogalamycin, nogalamycin analogs, and adriamycin to cells in different cell cycle phases. Cancer Research 1980; 40: 3437–3442
  • Braun J., Hahn G. M. Enhanced cell killing by bleomycin and 43° hyperthermia and the inhibition of recovery from potentially lethal damage. Cancer Research 1975; 35: 2921–2927
  • Chuang R. Y., Chuang L. F., Kawahata R. T., Israel M. Effect of N-trifluoroacetyladriamycin-14-valerate on 3H thymidine uptake and DNA synthesis of human lymphoma cells. Journal of Biological Chemistry 1983; 258: 1062–1065
  • Clarkson J. M., Humphrey R. M. The effect of adriamycin on cell cycle progression and DNA replication in Chinese hamster ovary cells. Cancer Research 1977; 37: 200–205
  • Dasdia T., DiMarco A., Goffredi M., Minghetti A., Necco A. Ion level and calcium fluxes in HeLa cells after adriamycin treatment. Pharmacological Research Communications 1979; 11: 19–29
  • DiMarco A. Adriamycin (NCS-123127); mode and mechanism of action. Cancer Chemotherapy Reports 1975; 6: 91–129
  • Durand R. E., Olive P. L. Flow cytometry studies of intracellular adriamycin in single cells in vitro. Cancer Research 1981; 41: 3489–3494
  • Hahn G. M. Potential for therapy of drugs and hyperthermia. Cancer Research 1979; 39: 2264–2268
  • Hahn G. M., Strande D. P. Cytotoxic effects of hyperthermia and adriamycin on Chinese hamster cells. Journal of the National Cancer Institute 1976; 57: 1063–1067
  • Hahn G. M., Braun J., Her-Kedcar I. Thermochemotherapy synergism between hyperthermia (42°-43°) and adriamycin (or bleomycin) in mammalian cell inactivation. Proceeding of the National Academy of Sciences, U.S.A. 1975; 72: 937–940
  • He Q., Skog S., Tribukait B. Thymidine kinase and its isoenzymes in relation to cell cycle and growth of ascites tumour cells. 1988, (submitted to Cell Tissue Kinetics)
  • Henle K. I., Leepers D. B. Effect of hyperthermia (45°) on macromolecular synthesis in Chinese hamster ovary cells. Cancer Research 1979; 39: 2665–2674
  • Inaba M., Kobayashi H., Sakurai Y., Johnson R. K. Active efflux of daunorubicin and adriamycin in sensitive and resistant sublines of P388 leukemia. Cancer Research 1979; 39: 2200–2203
  • Kim S. H., Kim J. H. Lethal effect of adriamycin on the division cycle of HeLa cells. Cancer Research 1972; 32: 323–325
  • Krishan A., Frei E. Effect of adriamycin on the cell cycle traverse and kinetics of cultured human lymphoblasts. Cancer Research 1976; 36: 143–150
  • Krishan A., Dutt K., Israel M., Ganapathi R. Comparative effects of adriamycin and N-trifluoroacethyl-adriamycin-14-valerate on cell kinetics, chromosomal damage, and macromolecular synthesis in vitro. Cancer Research 1981; 41: 2745–2750
  • Magin R., Cycyk R. L., Letterst C. L. Distribution of adriamycin in mice under conditions of local hyperthermia which improves systemic drug therapy. Cancer Treatment Reports 1980; 64: 203–210
  • Marmor J. B. Interactions of hyperthermia and chemotherapy in animals. Cancer Research 1979; 39: 2269–2276
  • Marmor J. B., Kozak D., Hahn G. M. Effect of systemically administered bleomycin or adriamycin with local hyperthermia on primary tumor and lung metastases. Cancer Treatment Reports 1979; 63: 1279–1290
  • Meriwether W. D., Bachur N. R. Inhibition of DNA and RNA metabolism by daunorubicin and adriamycin in L 1210 mouse leukemia. Cancer Research 1982; 32: 1137–1142
  • Mivechi N. F., Dewey W. C. DNA polymerase and activities during the cell cycle and their role in heat radiosensitization in Chinese hamster ovary cells. Radiation Research 1985; 103: 337–350
  • Momparter R. L., Karon M., Siegel S. E., Avila F. Effect of adriamycin on DNA, RNA, and protein synthesis in cell-free systems and intact cells. Cancer Research 1976; 36: 2891–2895
  • Mondovi B., Agro A. F., Rotilio G., Strom R., Moricca G., Franelli A. R. The biochemical mechanism of selective heat sensitivity of cancer cells. II. Studies on nucleic acids and protein synthesis. European Journal of Cancer 1969; 5: 137–146
  • Murphee S. A., Tritton T. R., Smith A. C., Sartorelli C. Adriamycin-induced changes in the surface membrane of sarcoma ascites cells. Biochimica et Biophysica Acta 1981; 649: 317–324
  • Naito K., Skog S., Tribukait B., Andersson L. Cell cycle related 3H-thymidine uptake and its significance for the incorporation into DNA. Cell Tissue Kinetics 1987; 20: 447–457
  • Overgaard J. Combined adriamycin and hyperthermia treatment of a murine mammary carcinoma in vivo. Cancer Research 1976; 36: 3077–3081
  • Piper A. A., Tattersall M. H. N., Fox R. M. The activities of thymidine metabolizing enzymes during the cell cycle of a human lymphocyte cell line Laz-007 synchronized by centrifugal elutriation. Biochimica et Biophysica Acta 1980; 633: 401–405
  • Rice G. C., Hahn G. M. Modulation of adriamycin transport by hyperthermia as measured by fluorescence-activated cell sorting. Cancer Chemotherapeutics and Pharmacology 1987; 20: 183–187
  • Sauer H., Wilmanns W. Thymidine kinase. Methods of Enzymatic Analysis, H. U. Bergmeyer, J. Bergmeyer, M. Grassl. Verlag Chemie, Weinheim, Deerfield Beach, Florida 1983; vol. III: 468–473
  • Skog S., Tribukait B. Analysis of cell flow and cell loss following investigation of the total number of cells in the various parts of the cell cycle. Cell Tissue Kinetics 1985; 18: 427–444
  • Skovsgaard T. Transport and binding of daunorubicin, adriamycin and rubidazone in Ehrlich ascites tumor cells. Biochemical Pharmacology 1977; 26: 215–222
  • Tribukait B., Moberger G., Zetterberg A. Methodological aspects of rapid-flow cytofluorometry for DNA analysis of human urinary bladder cells. Pulse-Cytophotometry, C. A. M. Haanen, H. F. P. Hillen, J. M. C. Wessels. European Press, Medicon, GhentBelgium 1975; 50–60, Part I
  • Tritton T. R., Yee G. The anticancer agent adriamycin can be actively cytotoxic without entering cells. Science 1982; 217: 248–250
  • Tritton T. R., Murphree S. A., Sartorelli A. C. Adriamycin: a proposal on the specificity of drugs action. Biochemistry and Biophysics Research Communications 1987; 84: 802–808
  • Wang J. J., Chervinsky D. S., Rosen J. M. Comparative biochemical studies of adriamycin and daunomycin in leukemic cells. Cancer Research 1972; 32: 511–515
  • Warters R. L., Stone L. Histone protein and DNA synthesis in HeLa cells after thermal shock. Journal of Cellular Physiology 1984; 118: 153–160
  • Westra A., Dewey W. C. Variation in sensitivity to heat shock during the cell-cycle of Chinese hamster cells in vitro. International Journal of Radiation Biology 1971; 19: 467–477
  • Wohlmeter R. M., Plagemann P. G. W. The roles of transport and phosphorylation in nutrient uptake in cultured animal cells. International Reviews of Cytology 1980; 64: 171–240
  • Wong R. S. L., Dewey W. C. Molecular studies on the hyperthermic inhibition of DNA synthesis in Chinese hamster ovary cells. Radiation Research 1982; 92: 370–395

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.