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Original Article

Short communication: The effect of in vivo GSH depletion on thermosensitivity, radiosensitivity and thermal radiosensitization

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Pages 951-955 | Received 14 Aug 1989, Accepted 15 Dec 1989, Published online: 09 Jul 2009

References

  • Bump E. A., Yu N. Y., Brown J. M. The use of drugs which deplete intracellular glutathione in hypoxic cell radiosensitization. International Journal of Radiation Oncology, Biology, Physics 1982; 8: 439–442
  • Freeman M. L., Meredith M. J. The effect of GSH depletion on thermal radiosensitization. International Journal of Radiation Oncology, Biology, Physics 1987; 13: 1371–1375
  • Freeman M. L., Meredith M. J. Subcellular localization of glutathione and thermal sensitivity. Radiation Research 1988; 115: 461–471
  • Freeman M. L., Malcolm A. W., Meredith M. J. Role of glutathione in cell survival after hyperthermic treatment of Chinese hamster ovary cells. Cancer Research 1985a; 45: 6308–6313
  • Freeman M. L., Malcolm A. W., Meredith M. J. Glutathione pool size affects cell survival after hyperthermic treatment. Cell Biology and Toxicology 1985b; 1: 213–221
  • Hissin P. J., Hilf R. A fluorometric method for determination of oxidized and reduced glutatione in tissues. Analytical Biochemistry 1976; 74: 214–226
  • Jones E. L., Lyons B. E., Douple E. B., Dain B. J. Thermal enhancement of low dose rate irradiation in a murine tumour system. International Journal of Hyperthermia 1989a; 5: 509–523
  • Jones E. L., Lyons B. E., Douple E. B., Filimonov A., Dain B. J. Response of a brachytherapy model using 125Iodine in a murine tumor system. Radiation Research 1989b; 118: 112–130
  • Kimler B. F., Sinclair W. K., Elkind M. M. N-ethylmaleimide sensitization of x-irradiated hypoxic Chinese hamster cells. Radiation Research 1977; 71: 204–213
  • Konings A. W. T., Penninga P. On the importance of the level of gluthathione and the activity of the pentose phosphate pathway in heat sensitivity and thermotolerance. International Journal of Radiation Biology 1985; 48: 409–422
  • Kramer R. A., Soble M., Howes A. E., Montoya V. P. The effect of glutathione (GSH) depletion in vivo by buthionine sulfoximine (BSO) on the radiosensitization of SR 2508. International Journal of Radiation Oncology, Biology, Physics 1989; 16: 1325–1329
  • Lilly M. B., Carroll A. J., Prochal J. Lack of association between glutathione content and development of thermal tolerance in human fibroblasts. Radiation Research 1986; 106: 41–46
  • Mitchell J. B., Russo A. Thiols, thiol depletion, and thermosensitivity. Radiation Research 1983; 95: 471–485
  • Mitchell J. B., Russo A., Biaglow J. E., McPherson S. Cellular glutathione depletion by diethyl maleate or buthionine sulfoximine: no effect of glutathione depletion on the oxygen enhancement ratio. Radiation Research 1983a; 96: 422–428
  • Mitchell J. B., Russo A., Kinsella T. J., Glatstein E. Glutathione elevation during thermotolerance induction and thermosensitization by glutathione depletion. Cancer Research 1983b; 43: 987–991

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