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International Journal of Hyperthermia Volume 7, 1991 - Issue 1
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Original Article

A differential low pH effect on tumour cells grown in vivo and in vitro when treated with hyperthermia

J. G. Rhee Department of Radiation Oncology, University of Maryland School of Medicine, 655 W. Baltimore St, 6-015 BRB, Baltimore, MD, 21201, USA
,
H. A. Eddy Department of Radiation Oncology, University of Maryland School of Medicine, 655 W. Baltimore St, 6-015 BRB, Baltimore, MD, 21201, USA
,
O. M. Salazar Department of Radiation Oncology, University of Maryland School of Medicine, 655 W. Baltimore St, 6-015 BRB, Baltimore, MD, 21201, USA
,
J. C. Lyons Department of Therapeutic Radiology, University of Minnesota Medical School, UMHC Box 494, Minneapolis, MN, 55455, USA
&
C. W. Song Department of Therapeutic Radiology, University of Minnesota Medical School, UMHC Box 494, Minneapolis, MN, 55455, USA
Pages 75-84 | Received 14 Mar 1989, Accepted 30 Mar 1990, Published online: 09 Jul 2009

References

  • Bichel P., Overgaard J. Hyperthermic effect on exponential and plateau ascites and tumor cells in vitro dependent on environmental pH. Radiation Research 1977; 70: 449–454
  • Chu G. L., Dewey W. C. The role of low intracellular or extracellular pH in sensitization to hyperthermia. Radiation Research 1988; 11: 154–167
  • Dobrucki J., Bleehen N. M. The effect of cell-to-cell interaction on heat sensitivity of HT29 human tumour cells. Proceedings of the 4th International Symposium on Hyperthermic Oncology 1984; 1: 57–60
  • Durand R. E. Effects of hyperthermia on the cycling, noncycling, and hypoxic cells of irradiated and unirradiated multicell spheroids. Radiation Research 1978; 75: 373–384
  • Freeman M. L., Dewey W. C., Hopwood L. E. Effect of pH on hyperthermic cell survival: Brief communication. Journal of the National Cancer Institute 1977; 58: 1837–1839
  • Freeman M. L., Boone M. L. M., Ensley A. E., Gillette D. V. M. The influence of environmental pH on the interaction and repair of heat and radiation damage. International Journal of Radiation Oncology, Biology, Physics 1981; 7: 761–764
  • Gerweck L. E. Modification of cell lethality at elevated temperatures. The pH effect. Radiation Research 1977; 70: 224–235
  • Gerweck L. E., Richards B. Influence of pH on the thermal sensitivity of cultured human glioblastoma cells. Cancer Research 1981; 4: 845–849
  • Gerweck L. E., Dahlberg W. K., Greco B. Effect of pH on single or fractionated heat treatments at 42–45°C. Cancer Research 1983; 43: 1163–1167
  • Hahn G. M., Shiu E. C. Adaptation to low pH modifies thermal and thermochemical responses of mammalian cells. International Journal of Hyperthermia 1986; 2: 379–387
  • Kang M. S., Song C. W. The effect of hyperthermia in cell survival in mouse tumor without blood flow. British Journal of Radiology 1980; 53: 606–607
  • LI G. C., Shiu E. C., Hahn G. M. Recovery of cells from heat-induced potentially lethal damage: Effects of pH and nutrient environment. International Journal of Radiation Oncology, Biology, Physics 1980; 6: 577–582
  • Meyer K. R., Hopwood L. E., Gillette E. L. The thermal response of mouse adenocarcinoma cells at low pH. European Journal of Cancer 1979; 1: 1219–1222
  • Overgaard J. Influence of extracellular pH on the viability and morphology of tumor cells exposed to hyperthermia. Journal of the National Cancer Institute 1976; 56: 1243–1250
  • Rhee J. G., Song C. W., Levitt S. H. Changes in thermosensitivity of mouse mammary carcinoma following hyperthermia. in vivo. Cancer Research 1982; 4: 4485–4489
  • Rhee J. G., Kim T. H., Levitt S. H., Song C. W. Changes in acidity of mouse tumor by hyperthermia. International Journal of Radiation Oncology, Biology, Physics 1984; 1: 393–399
  • Rhee J. G., Schuman V. L., Song C. W., Levitt S. H. Difference in the thermotolerance of mouse mammary carcinoma cells in vivo and. in vitro. Cancer Research 1987; 47: 2571–2575
  • Rhee J. G., Eddy H. A., Salazar O. M., Lyons J. C., Sonc C. W. Reversible heat sensitivity of mouse mammary carcinoma by a modified microenvironment. Hyperthermic Oncology 1988, T. Sugahara, M. Saito. Taylor & Francis, London 1988; Vol. 1: 32–33
  • Rofstad E. K., Wahl A., Brustad T. Heat response of human melanoma multicellular spheroids: comparisons with single cells and xenografted tumors. Radiation Research 1985; 10: 324–335
  • Stewart J. R., Gibbs F. A., Jr, Lehman C. M., Peck J. W., Egger M. J. Change in the in vivo hyperthermic response resulting from the metabolic effects of temporary vascular occlusion. International Journal of Radiation Oncology, Biology, Physics 1983; 9: 197–201
  • Urano M., Gerweck L. E., Epstein R., Cunningham M., Suit H. D. Response of a spontaneous murine tumor to hyperthermia: factors which modify the thermal response. in vivo. Radiation Research 1980; 83: 312–322
  • Wike-Hooley J. L., Haveman J., Reinhold H. S. The relevance of tumour pH to the treatment of malignant disease. Radiotherapy and Oncology 1984; 2: 343–366

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