Enhancement of sensitivity to hyperthermia by Lonidamine in human cancer cells

References

• Band P. R., Maroun J., Pritchard K., Stewart D., Coppin C. M., Wilson K., Eisenhauer E. A. Phase II study of Lonidamine in patients with metastatic breast cancer. Cancer Treatment Reports 1986; 70: 1305–1310
   PubMedGoogle Scholar
• Bigner D. D., Bigner S. H., Ponten J., Westermark B., Mahaley M. S., Rvoslahti E., Hershchman H., Eng L. F., Wikstrand C. J. Heterogeneity of genotypic and phenotypic characteristics of 15 permanent cell lines derived from human glioma. Journal of Neuropathology and Experimental Neurology 1981; 40: 201–229
   PubMed Web of Science ®Google Scholar
• Calderwood S. K. Role of energy in cellular responses to heat. Temperature and Animal Cells, K. Bowler, B. J. Fuller. Council of Biology, Cambridge 1987; 212–233
   Google Scholar
• Carapella C. M., Iandolo B., Chiare S. D., Riccio A. Lonidamine in primary malignant brain tumours. Oncology 1984; 41: 82–85
   PubMedGoogle Scholar
• Cavaliere R., Di Filippo F., Varanese A., Carlini S., Calabro A., Aloe L., Piarulli L. Lonidamine and hyperthermia: clinical experience in melanoma. Oncology 1984; 41: 116–120
   PubMed Web of Science ®Google Scholar
• Chitnis M., Juvekar A., Awankar M., Advani S. Inhibition of DNA synthesis by Lonidamine and hyperthermia in human chronic myeloid leukema cells. Anti Cancer Research 1986; 6: 749–752
   PubMedGoogle Scholar
• Evanochko W. T., Ng T. C., Lilly M. B., Lawson A. J., Corbett T. H., Durant J. R., Glickson J. D. In vivo 31P NMR study of the metabolism of murine 16/C adenocarcinoma and its response to chemotherapy, X-irradiation and hyperthermia. Proceedings of the National Academy of Sciences, USA 1983; 80: 334–338
   PubMedGoogle Scholar
• Feeley M. M., Raaphorst G. P., Danjoux C. E., Maroun M., Fischer B., Martin L. The response of human cells and rodent cells to Lonidamine radiation and hyperthermia. Clinical and Investigational Medicine 1988a; C96: 11
   Google Scholar
• Feeley M. M., Raaphorst G. P., Danjoux C. E., Maroun J., Fischer B., Martin L. The response of human cells and rodent cells to Lonidamine radiation and hyperthermia. Clinical and Investigational Medicine 1988b; C96: 11
   Google Scholar
• Floridi A., Gambacurta A., Bagnato A., Bianchi C., Paggi M. G., Silvestrini B., Caputo A. Modulation of Adriamycin uptake by Lonidamine in Ehrlich ascites tumour cells. Experimental and Molecular Pathology 1988; 499: 421–431
   Google Scholar
• Floridi A., Paggi M. G., Marcante M. L., Silvestrini B., Caputo A., de Martino C. Lonidamine a selective inhibitor of aerobic glycolysis of murine tumour cells. Journal of the National Cancer Institute 1981; 66: 497–499
   PubMed Web of Science ®Google Scholar
• Freeman M. L., Raaphorst G. P., Hopewood L. E., Dewey W. C. The effect of pH on cell lethality induced by hyperthermic treatment for cancer. Cancer 1980; 45: 61–70
   Google Scholar
• Gerweck L. E., Dahlberg W. C., Epstein L., Shimm D. S. Influence of nutrient and energy deprivation on cellular response to single and fractionated heat treatments. Radiation Research 1984; 99: 573–581
   PubMed Web of Science ®Google Scholar
• Gerweck L. E. Modifiers of thermal effects: environmental factors. Hyperthermia and Oncology, M. Urano, E. Douple, 1988; vol. 1: 83–98, (Utrecht: VSP)
   Google Scholar
• Hahn G. M., van Kersen I., Silvestrinni B. Inhibition of the recovery from potentially lethal damage by Lonidamine. British Journal of Cancer, 50: 657–660
   PubMedGoogle Scholar
• Haveman J., Hahn G. M. The role of energy in hyperthermia induced mammalian cell inactivation. A study of the effects of glucose starvation and an uncoupler of oxidative phosphorylation. Journal of Cell Physiology 1981; 108: 237–241
   Google Scholar
• Henle K. J., Nagle W. A., Moss A. J., Herman T. S. Cellular ATP content of heated Chinese hamster ovary cells. Radiation Research 1984; 97: 630–639
   PubMed Web of Science ®Google Scholar
• Kim S. H., Kim J. H., Hahn E. W., Ensign N. A. Selective killing of glucose and oxygen deprived HeLa cells by hyperthermia. Cancer Research 1980; 40: 3459–3462
   PubMed Web of Science ®Google Scholar
• Kim J. H., Kim S. H., Alfieri A., Young C. W., Silvestrini G. Lonidamine: A hyperthermic sensitizer of HeLa cells in culture and of the Meth-A tumour in vivo. Oncology 1984a; 41: 30–35
   PubMed Web of Science ®Google Scholar
• Kim J. H., Alfieri A. A., Kim S. H., Young C. W., Silvestrini B. Radiosensitization of Meth-A fibrosarcoma in mice by Lonidamine. Oncology 1984b; 41: 36–38
   PubMed Web of Science ®Google Scholar
• Kim J. H., Alfieri A. A., Kim S. H., Young C. W. Potentiation of radiation effects on two murine tumours by Lonidamine. Cancer Research 1986; 46: 1120–1123
   PubMed Web of Science ®Google Scholar
• Kim J. H., Kim S. H., He S. Q., Alfieri A. A., Young C. W. Potentiation of radiation effects on multicellular tumour spheroids (MTS) of HeLa cells by Lonidamine. Journal of Radiation Oncology 1989; 16: 1277–1280
   PubMed Web of Science ®Google Scholar
• Krause C. J., Carey T. E., Ott R. W., Hurbis C., Clatchey M. C., Regezi K. Z. Human squamous cell carcinoma. Establishment and characterization of new permanent cell lines. Archives of Otolaryngology 1981; 107: 703–710
   PubMedGoogle Scholar
• Magno L., Terraneo F., Ciottoli G. B. Lonidamine and radiotherapy in head and neck cancers. Oncology 1984; 41: 113–115
   PubMedGoogle Scholar
• de Martino C., Battelli T., Paggi M. G., Nista A., Marcante M. L., Atri S. D., Malorni W., Gallo M., Floridi A. Effects of Lonidamine on murine and human tumour cells in vitro. A morphological and biochemical study. Oncology 1984; 41: 15–29
   PubMedGoogle Scholar
• Privitera G., Ciottoli G. B., Pataine C., Palmucci T., Tafuri G., Marletta F., DeLuca B., Magnani F., DeGregorio M., Greco S. Phase II double-blind randomized study of Lonidamine and radiotherapy in epidermoid carcinoma of the lung. Radiotherapy and Oncology 1987; 10: 285–290
   PubMed Web of Science ®Google Scholar
• Raaphorst G. P., Azzam E. I., Borsa J., Einspenner M., Vadasz J. Hyperthermia in a differentiated murine erythroleukemia cell line II. Effect of heat on heme induction by radiation. International Journal of Radiation Biology 1983; 44: 343–352
   Google Scholar
• Raaphorst G. P., Broski A. P., Azzam E. I. Sensitivity to heat, radiation and heat plus radiation of Chinese hamster cells, synchronized by mitotic selection, thymidine block or hydroxyurea. Journal of Thermal Biology 1985; 10: 177–181
   Google Scholar
• Raaphorst G. P., Feeley M. M., Danjoux C. E., Martin L., Maroun J., DeSanctis A. J. The effect of Lonidamine on radiation and thermal responses of human and rodent cell lines. International Journal of Radiation Oncology 1990a; 20: 509–515, 1991
   Google Scholar
• Raaphorst G. P., Feeley M. M., Heller D. P., Danjoux C. E., Martin L., Maroun J., DeSanctis A. J. Lonidamine can enhance the cytotoxic effect of cisplatin in human tumour cells and rodent cells. Anticancer Research 1990b; 10: 923–928
   PubMedGoogle Scholar
• Rosbe K. W., Brann T. W., Holden S. A., Teicher B. A., Frei E., III. Effect of Lonidamine on the cytotoxicity of four alkylating agents in vitro. Cancer Chemotherapy and Pharmacology 1989; 25: 32–36
   PubMed Web of Science ®Google Scholar
• Sijens P. E., Bovee W. M. M. J., Koole P., Schipper J. Phosphorous NMR study of response of a murine tumour to hyperthermia as a function of treatment time and temperature. International Journal of Hyperthermia 1989; 5: 351–357
   PubMed Web of Science ®Google Scholar
• Silvestrini B., Hahn G. M., Cioli V., De Martino C. Effects of Lonidamine alone or combined with hyperthermia in some experimental cell and tumour systems. British Journal of Cancer 1983; 47: 221–235
   PubMedGoogle Scholar
• Silvestrini B., Palazzo G., DeGregorio M. Lonidamine and related compounds. Progress in Medicinal Chemistry, G. P. Ellis, G. P. West, 1984; vol. 2: 111–135
   Google Scholar
• Stryker J. A., Gerweck L. E. Lonidamine-induced pH dependent inhibition of cellular oxygen utilization. Radiation Research 1988; 113: 356–3611
   PubMed Web of Science ®Google Scholar
• Szekely J. G., Lobreau A. U., Delaney S., Raaphorst G. P., Feeley M. M. Morphological effects of Lonidamine on human tumour cells. Scanning Electron Microscopy 1989; 3: 681–693
   Google Scholar
• Westra A., Dewey W. C. Variation in sensitivity to heat shock during the cell cycle of Chinese hamster cells in vitro. International Journal of Radiation Biology 1971; 19: 467–477
   Web of Science ®Google Scholar
• Wike-Hooley J. L., Haveman J., Reinhold H. S. The relevance of tumour pH to the treatment of malignant disease. Radiotherapy and Oncology 1984; 2: 343–366
   PubMed Web of Science ®Google Scholar