31
Views
30
CrossRef citations to date
0
Altmetric
Original Article

Phase III evaluation of doxorubicin and whole-body hyperthermia in dogs with lymphoma

, , , , , , , , , , & show all
Pages 187-197 | Received 13 May 1991, Accepted 04 Sep 1991, Published online: 09 Jul 2009

References

  • Baba H., Strebel F., Wondergem J., Stephens L. C., Alonso M., Newman R. A., Bull J. M. Effect of whole body hyperthermia combined with adriamycin on tumor and normal tissue in rats. North American Hyperthermia Group Proceedings 1989; 34, Abstr
  • Bates D. A., Mackillop W. J. Hyperthermia, adriamycin transport and cytotoxicity in drug-sensitive and resistant Chinese hamster ovary cells. Cancer Research 1986; 46: 5477–5481
  • Birmelin M., Hinkelbein W., Oehlert W., Wannenmacher M. Cardiotoxicity of moderate whole body hyperthermia, doxorubicin and combined treatment in rats. Recent Results in Cancer Research 1988; 109: 83–88
  • BMDP Statistical Software Inc. BMDP Statistical Software Manual, vol. 2: to accompany the 1990 software release. University of California Press, Berkeley, CA 1990
  • Bull J. M. C. A review of systemic hyperthermia. Frontiers in Radiation Therapy and Oncology 1984; 18: 1–22
  • Burns C. P., Lambert B. J., Haugstad B. N., Guffy M. M. Influence of rate of heating on thermosensitivity of L1210 leukemia: membrane lipids and Mr 70,000 heat shock protein. Cancer Research 1986; 46: 1882–1887
  • Cox D. R., Oakes D. Analysis of Survival Data. Chapman & Hall, London 1984
  • Dahl O. Hyperthermic potentiation of doxorubicin and 4-epi-doxorubicin in a transplantable neurogenic rat tumor (BT4A) in BD IX rats. International Journal of Radiation Oncology, Biology and Physics 1983; 9: 359–364
  • Dahl O. Interaction of hyperthermia and chemotherapy. Recent Results in Cancer Research 1988; 107: 157–169
  • Engelhardt R. Summary of recent clinical experience in whole body hyperthermia combined with chemotherapy. Recent Results in Cancer Research 1988; 107: 200–204
  • Gerard H., Van Echo D. A., Whitacre M., Ashman M., Helrich M., Foy J., Ostrow S., Wiernik P. H., Aisner J. Doxorubicin, cyclophosphamide, and whole body hyperthermia for treatment of advanced soft tissue sarcoma. Cancer 1984; 53: 2585–2591
  • Hahn G. M. Thermal enhancement of the actions of anticancer agents. Hyperthermia and Cancer. Plenum Press, New York 1982; 55–85
  • Hahn G. M., Braun J., Har-Kedar I. Thermochemotherapy: synergism between hyperthermia (42–43°C) and adriamycin (or bleomycin) in mammalian cell inactivation. Proceedings of the National Academy of Sciences 1975; 72: 937–940
  • Hahn G. M., Strand D. P. Cytotoxic effects of hyperthermia and adriamycin on Chinese hamster cells. Journal of the National Cancer Institute 1976; 57: 1063–1067
  • Herman T. S., Gerner E. W., Magun B. E., Stickney D., Sweets C. C., White D. M. Rate of heating as a determinant of hyperthermic cytotoxicity. Cancer Research 1981; 41: 3519–3523
  • Hoppe R. T. The non-Hodgkin's lymphomas: pathology, staging and treatment. Current Problems in Cancer 1987; 11: 364–446
  • Kaplan E. L., Meier P. Nonparametric estimation from incomplete observations. Journal of the American Statistical Association 1958; 53: 457–481
  • Kapp D. S., Lord P. F. Thermal tolerance to whole body hyperthermia. International Journal of Radiation Oncology, Biology and Physics 1983; 9: 917–921
  • Klein M. K., Dewhirst M. W., Fuller D. J. M. Whole body hyperthermia and heat sensitizing drugs: a pilot study in canine lymphoproliferative disease. International Journal of Hyperthermia 1987; 3: 187–198
  • MacEwen E. G., Hayes A. A., Matus R. E., Kurzman I. Evaluation of some prognostic factors for advanced multicentric lyphosarcoma in the dog: 147 cases (1978–1981). Journal of the American Veterinary Association 1987; 190: 564–568
  • Meyer R. E., Page R. L., Thrall D. E., Dewhirst M. W. Determination of continuous atracurium infusion rate in dogs undergoing whole-body hyperthermia. Cancer Research 1986; 46: 5599–5601
  • Nagaoka A., Kawasaki S., Karino Y., Hiraki Y., Nakanishi T. In vivo effects of hyperthermia on the cellular uptake of adriamycin. Journal of Radiation Research 1987; 28: 262–267
  • Novotney C. A., Page R. L., Macy D. W., Dewhirst M. W., Ogilvie G. K., Withrow S. J., McEntee M. C., Heidner G. L., Allen S. A., Thrall D. E., Gillette E. L. Phase I evaluation of doxorubicin and whole body hyperthermia in dogs with lymphosarcoma. Journal of Veterinary Internal Medicine 1990, In press
  • Owen L. TNM Classification of Tumors of Domestic Animals. GenevaSwitzerland 1980
  • Page R. L., Meyer R. E., Thrall D. E., Dewhirst M. W. Cardiovascular and metabolic response of tumor bearing dogs to whole body hyperthermia. International Journal of Hyperthermia 1987; 3: 315–326
  • Page R. L., Macy D. W., Thrall D. E., Allen S. A., Heidner G. L., Sim D. A., McGee M. L., Gillette E. L. Unexpected toxicity associated with body surface area for dosing melphalan in the dog. Cancer Research 1988; 48: 288–290
  • Postorino N. C., Susaneck S. J., Withrow S. J., Macy D. W., Harris C. Single agent therapy with adriamycin for canine lymphoma. Journal of the American Animal Hospital Association 1989; 25: 221–225
  • Riviere J. E., Page R. L., Rogers S. A., Chang S. K., Dewhirst M. W., Thrall D. E. Nonuniform alteration of cis-diamminedichloroplatinum(II) tissue distribution in dogs with whole body hyperthermia. Cancer Research 1990; 50: 2075–2080
  • Robins H. I. Role of whole body hyperthermia in the treatment of neoplastic disease: its current status and future prospects. Cancer Research 1984; 44: 4878s–4883s
  • Rosner B. Fundamentals of Biostatistics, 3rd edn. P. W. S. Kent, Boston 1990
  • SAS Institute Inc. SAS/STat Guide for Personal Computers, 6 edition. SAS Institute Inc., Cary, NC 1987, Version
  • Thrall D. E., Page R. L., Dewhirst M. W., Macy D. W., McLeod D. A., Scott R. J., Allen S. A., Gillette E. L. Whole body hyperthermia in dogs using a radiant heating device: effect of heating technique on temperature uniformity. International Journal of Hyperthermia 1989; 5: 137–143
  • Thrall D. E., Page R. L., Dewhirst M. W., Meyer R. E., Hoopes P. J., Kornegay J. N. Temperature measurements in normal and tumor tissue in dogs undergoing whole body hyperthermia. Cancer Research 1986; 46: 6229–6235
  • Thrall D. E., Page R. L., McLeod D. A. Use of extremity insulation to reduce temperature nonuniformity during whole body hyperthermia. Cancer Research 1987; 47: 5880–5882
  • Toffoli G., Bevilacqua C., Franceschin A., Boiocchi M. Effect of hyperthermia on intracellular drug accumulation and chemosensitivity in drug-sensitive and drug-resistant P388 leukemia cell lines. International Journal of Hyperthermia 1989; 5: 163–172
  • Wallner K. E., Banda M., Li G. C. Hyperthermic enhancement of cell killing by mitomycin c in mitomycin c-resistant Chinese hamster ovary cells. Cancer Research 1987; 47: 1308–1312
  • Wallner K. E., De Gregorio M. W., Li G. C. Hyperthermic potentiation of cis-diammine dichloroplatinum(II) cytotoxicity in Chinese hamster ovary cells resistant to the drug. Cancer Research 1986; 46: 6242–6245
  • Wallner K. E., Li G. C. Adriamycin resistance, heat resistance and radiation response in Chinese hamster fibroblasts. International Journal of Radiation Oncology, Biology and Physics 1986; 12: 829–833
  • Weshler Z., Kapp D. S., Lord P. F., Hayes T. Development and decay of systemic thermotolerance in rats. Israel Journal of Medical Science 1989; 25: 15–19
  • Wilke A. V., Jenkins C., Milligan A. J., Legendre A., Frazier D. L. Effect of hyperthermia on normal tissue toxicity and on adriamycin pharmacokinetics in dogs. Cancer Research 1991; 51: 1680–1683

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.