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Original Article

Potentiation of hyperthermia in a murine tumour by metabolic inhibitors rhodamine 123 and 2-deoxy-D-glucose or 5-thio-D-glucose

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Pages 475-483 | Received 06 Sep 1989, Accepted 14 Jan 1992, Published online: 09 Jul 2009

References

  • Arbeit J. M., Toy B. J., Karczmar G. S., Huebesch A., Weiner M. W. Inhibition of tumor high-energy phosphate metabolism by insulin combined with rhodamine 123. Surgery 1988; 104: 161–170
  • Bernal S. D., Lampidis T. J., McIsaac R. M., Chen L. B. Anticarcinoma activity in vivo of rhodamine 123: a mitochondrial-specific dye. Science 1983; 222: 169–172
  • Bernal S. D., Lampidis T. J., Summerhayes I. C., Chen L. B. Rhodamine-123 selectively reduces clonal growth of carcinoma cell in vitro. Science 1982; 218: 1117–1119
  • Brown J. Effects of 2-deoxy-D-glucose on carbohydrate metabolism. Review of the literature and studies in the rat. Metabolism 1962; 11: 1098–1112
  • Chen L. B., Summerhayes I. C., Johnson L. V., Walsh M. L., Bernal S. D., Lampidis T. Probing mitochondria in living cells with rhodamine 123. Cold Spring Harbor Symposia on Quantitative Biology 1982; 46: 141–155
  • Clifton K. H., Briggs R. C., Stone H. B. Quantitative radiosensitivity studies of solid carcinomas in vivo: methodology and effect of anoxia. Journal of the National Cancer Institute 1966; 36: 965–974
  • Clifton K. H., Draper N. R. Survival-curves of solid transplantable tumors irradiated in vivo: a method of determination and statistical evaluation; comparison of cell-survival and 32P uptake into DNA. International Journal of Radiation Biology 1963; 7: 515–535
  • Cox D. R. Regression models and life tables with discussion. Journal of the Royal Statistical Society B 1972; 34: 187–220
  • Gerweck L. E., Dahlberg W. K., Epstein L. F., Shimm D. S. Influence of nutrient and energy deprivation on cellular response to single and fractionated heat treatments. Radiation Research 1984; 99: 573–581
  • Gibbs F. A., Peck J. W., Dethlefsen L. A. The importance of intratumor uniformity in the study of radiosensitizing effects of hyperthermi in vivo. Radiation Research 1981; 87: 187–197
  • Gridley D. S., Nutter R. L., Mantik D. W., Slater J. M. Hyperthermia and radiation in vivo: Effect of 2-deoxy-D-glucose. International Journal of Radiation Oncology, Biology and Physics 1985; 11: 567–574
  • Haveman J., Hahn G. M. The role of energy in hyperthermia-induced mammalian cell inactivation: a study of the effects of glucose starvation and an uncoupler of oxidative phosphorylation. Journal of Cellular Physiology 1981; 107: 237–241
  • Herman T. S., Teicher B. A., Cathcart K. N. S., Kaufmann M. E., Lee J. B., Lee M. Effect of hyperthermia on cis-diamminedichloroplatinum (II) (rhodamine 123)2 [tetrachloroplatinum (II)] in a human squamous cell carcinoma line and a cis-diammine-dichloroplatinum (II)-resistant subline. Cancer Research 1988a; 48: 5101–5105
  • Herman T. S., Teicher B. A., Chan V., Collins L. S., Kaufmann M. E., Loh C. Effect of hyperthermia on the action of cis-diamminedichloroplatinum (II) (rhodamine 123)2 [tetrachoroplatinum (II)], rhodamine 123, and potassium tetrachloroplatinate in vitro an in vivo. Cancer Research 1988b; 48: 2335–2341
  • Johnson L. V., Walsh M. L., Chen L. B. Localization of mitochondria in living cells with rhodamine 123. Proceedings of the National Academy of Science USA 1980; 77: 990–994
  • Jones E. L., Lyons B. E., Douple E. B., Filimonov A., Dain B. J. Response of brachytherapy model using 125iodine in a murine tumor system. Radiation Research 1989; 118: 112–130
  • Kern K. A., Norton J. A. Inhibition of established rat fibrosarcoma growth by the glucose antagonist 2-deoxy-D-glucose. Surgery 1987; 102: 380–385
  • Kim J. H. Modification of thermal effects: chemical modifiers, thermal effects on cells and tissues. Hyperthermia and Oncology 1988 Thermal Effects on Cells and Tissues, M. Urano, E. Douple. VSP, UtrechtThe Netherlands 1988; Vol. 1: 99–119
  • Kim J. H., Kim S. H., Alfieri A. A. Interaction of rhodamine 123 and hyperthermia in HeLa cells in culture. International Journal of Hyperthermia 1985; 1: 247–253
  • Kim J. H., Kim S. H., Hahn E. W., Song C. W. 5-Thio-D-glucose selectively potentiates hyperthermic killing of hypoxic tumor cells. Science 1978; 200: 206–207
  • Kim S. H., Kim J. H., Hahn E. W., Ensign N. A. Selective killing of glucose and oxygen-deprived HeLa cells by hyperthermia. Cancer Research 1980; 40: 3459–3462
  • Lampidis T. J., Bernal S. D., Summerhayes I. C., Chen L. B. Selective toxicity of rhodamine 123 in carcinoma cell in vitro. Cancer Research 1983; 43: 716–720
  • Laszlo J., Humphreys S. R., Goldin A. Effects of glucose analogues (2-deoxy-D-galactose) on experimental tumors. Journal of the National Cancer Institute 1960; 24: 267–279
  • Lilly M. B., Ng T. C., Evanochko W. T., Katholi C. R., Kumar N. G., Elgavish G. A., Durant H. R., Hiramoto R., Ghanta V., Glickson J. D. Loss of high-energy phosphte following hyperthermia demonstrated by in vivo31P-nuclear magnetic resonance spectroscopy. Cancer Research 1984; 44: 633–638
  • Markoe A. M., Risch V. R., Emrich J., Fala S., Brady L. W. Tissue distribution and retention of 5-thio-D-glucose in animal tumor models. Cancer Clinnical Trials 1980; 3: 155–163
  • Modica-Napolitano J. S., Aprille J. R. Basis for the selective cytotoxicity of rhodamine 123. Cancer Research 1987; 47: 4361–4365
  • Pederson P. L. Tumor mitochondria and the bioenergetics of cancer cells. Progress in Experimental Tumor Research, D. F. H. Wallach. Karger, Basel 1978; Vol. 22: 190–274
  • Rao C. R. Linear Statistical Inference and Its Applications. John Wiley and Sons, New York 1973; 417–418
  • Rhee J. G., Lyons J. C., Song C. W. Heat response of mouse tumor cells treated with 5-thio-D-glucose and rhodamine 123. Abstracts of the Seventh Annual Meeting of the North American Hyperthermia Group. Radiation Research Society, Philadelphia 1987; 25
  • Song C. W., Clement J. J., Levitt S. H. Brief communication: preferential cytotoxicity of 5-thio-D-glucose against hypoxic tumour cells. Journal of the National Cancer Institute 1976; 57: 603–605
  • Song C. W., Clement J. J., Levitt S. H. Elimination of hypoxic protection by 5-thio-D-glucose in multicell spheroids. Cancer Research 1978a; 38: 4499–4503
  • Song C. W., Guertin D. P., Levitt S. H. Potentiation of cytotoxicity of 5-thio-D-glucose on hypoxic cells by hyperthermia. International Journal of Radiation Oncology, Biology and Physics 1979; 5: 965–970
  • Song C. W., Sung J. H., Clement J. J., Levitt S. H. Cytoxic effect of 5-thio-D-glucose on chronically hypoxic cells in multicell spheroids. British Journal of Cancer 1978b; 37: (Suppl. III), 136–140
  • Sridhar C. W., Koch C. J., Stroude E. C., Inch W. R. Cell survival in V79 multicell spheroids treated with dehydroascorbate, 5-thio-D-glucose and 2-deoxy-D-glucose. British Journal of Cancer 1978; 37: (Suppl. III), 141–144
  • Summerhayes I. C., Lampidis T. J., Bernal S. D., Nadakavukaren J. J., Nadakavukaren K. K., Shephard E. L., Chen L. B. Unusual retention of rhodamine 123 by mitochondria in muscle and carcinoma cells. Proceedings of the National Academy of Science USA 1982; 79: 5292–5296

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