7
Views
4
CrossRef citations to date
0
Altmetric
Original Article

Modification of intracellular pH and thermotolerance development by amiloride

&
Pages 511-522 | Received 19 Oct 1993, Accepted 21 Sep 1994, Published online: 09 Jul 2009

References

  • Aronson P. S. Kinetic properties of the plasma membrane Na+-H+ exchanger. Annual Review of Physiology 1985; 47: 545–560
  • Bassnett S., Reinisch L., Beebe D. C. Intracellular pH measurement using single excitation-dual emission fluorescence ratios. American Journal of Physiology 1990; 258: C171–C178
  • Boyarsky G., Ganz M. B., Sterzel R. B., Boron W. F. ph regulation in single glomerular mesangial cells. Acid extrusion in absence and presence of HCO3. American Journal of Physiology 1988; 255: C844–C856
  • Buckler K. J., Vaughan-Jones R. D. Application of a new pH-sensitive fluoroprobe (carboxy-SNARF-1) for intracellular pH measurement in small, isolated cells. Pflügers Archiv 1990; 417: 234–239
  • Calderwood S. K., Dickson J. A. pH and tumor response to hyperthermia. Advances in Radiation Biology 1983; 10: 135–190
  • Cassel D., Scharf O., Rotman M., Cragoe E. J., Jr, Katz M. Characterization of Na-linked and Naindependent Cl-/HCO3 exchange systems in Chinese hamster lung fibroblasts. The Journal of Biological Chemistry 1988; 263: 6122–6127
  • Chu G. L., Wang Z., Hyun W. C., Pershadsingh H. A., Fulwyler M. J., Dewey W. C. The role of intracellular pH and its variance in low pH sensitization of killing by hyperthermia. Radiation Research 1990; 122: 288–293
  • Chu G. L., Dewey W. C. Effect of hyperthermia on intracellular pH in chinese hamster ovary cells. Radiation Research 1987; 110: 439–449
  • Cook J. A., Fox M. H. Effects of acute pH 6·6 and 42·0°C heating on the intracellular pH of Chinese hamster ovary cells. Cancer Research 1988a; 48: 496–502
  • Cook J. A., Fox M. H. Development of thermotolerance and changes in intracellular pH in CHO cells heated at 45·0°C at pH 6·6. Radiation Research 1988b; 115: 106–114
  • Cook J. A., Fox M. H. Effects of chronic pH 6·6 on growth, intracellular pH, and response to 42·0°C hyperthermia of Chinese hamster ovary cells. Cancer Research 1988c; 48: 2417–2420
  • Cook J. A., Fox M. H. Intracellular pH measurements using flow cytometry with 1,4-diacetoxy-2,3-dicyanobenzene. Cytometry 1988d; 9: 441–447
  • Dickson J. A., Oswald B. E. The sensitivity of a malignant cell line to hyperthermia (42°C) at low intracellular pH. British Journal of Cancer 1976; 34: 262–271
  • Eden M., Haines B., Kahler H. The pH of rat tumors measure in vivo. Journal of the National Cancer Institute 1955; 16: 541–556
  • Gerweck L. E. Modification of cell lethality at elevated temperatures: the pH effect. Radiation Research 1977; 70: 224–235
  • Gerweck L. E., Jennings M., Richards B. Influence of pH on the response of cells to single and split doses of hyperthermia. Cancer Research 1980; 40: 4019–4024
  • Gleeson D., Smith N. D., Boyer J. L. Bicarbonate-dependent and -independent intracellular pH regulatory mechanisms in rat hepatocytes. Journal of Clinical Investigations 1989; 84: 312–321
  • Grinstein S., Rothstein A. Mechanisms of regulation of the Na/H exchanger. Journal of Membrane Biology 1986; 90: 1–12
  • Hofer K. G., Mivechi N. F. Tumor cell sensitivity to hyperthermia as a function of extracellular and intracellular pH. Journal of the National Cancer Institute 1980; 65: 621–625
  • Kampinga H. H. Thermotolerance in mammalian cells: protein denaturation and aggregation, and stress proteins. Journal of Cell Science 1993; 104: 11–17
  • Kim G. E., Lyons J. C., Song C. W. Effects of amiloride on intracellular pH and thermosensitivity. International Journal of Radiation Oncology, Biology and Physics 1991; 20: 541–549
  • Liu J.C-K. The role of intracellular pH regulation in heat sensitivity and thermotolerance of CHO cells. Ph.D. Dissertation, Colorado State University, Fort Collins, CO 1992
  • Lyons J. C., Kim G. E., Song C. W. Modification of intracellular pH and thermosensitivity. Radiation Research 1992; 129: 79–87
  • Miyakoshi J., Oda W., Hirata M., Fukuhori N., Inagaki C. Effects of amiloride on thermosensitivity of Chinese hamster cells under neutral and acidic pH. Cancer Research 1986; 46: 1840–1843
  • Miyakoshi J., Hirata M., Oda W., Cragoe E. J., Jr., Inagaki C. Sensitization to heat by amiloride analogues in Chinese hamster ovary cells. Japan Journal of Pharmacology 1987; 45: 281–283
  • Rabinovitch P. S., June C. H. Intracellular ionized calcium, membrane potential, and pH. Flow Cytometry. A Practical Approach, M. G. Ormerod. Oxford University Press, New York 1990; 161–185
  • Reinertsen K. V., Tonnessen T. I., Jacobsen J., Sandvig K., Olsnes S. Role of chloride/bicarbonate antiport in the control of cytosolic pH: cell line differences in activity and regulation of antiport. The Journal of Biological Chemistry 1988; 263: 11117–11125
  • Ruifrok A. C. C., Konings A. W. T. Effects of amiloride on hyperthermic cell killing of normal and thermotolerant mouse fibroblast LM cells. International Journal of Radiation Biology 1973; 52: 385–392
  • Tannock I. F., Rotin D. Acid pH in tumors and its potential for therapeutic exploitation. Cancer Research 1989; 49: 4373–4384
  • Thistlethwaite A. J., Leeper D. B., Moylan D. J., Nerlinger R. N. pH distribution in human tumors. International Journal of Radiation Oncology, Biology and Physics 1985; 11: 1647–1652
  • Van Erp P. E. J., Jansen M. J. J., De M., Jongh G. J., Boezeman J. B. M., Schalkwijk J. Ratiometric measurement of intracellular pH in cultured human keratinocytes using carboxy-SNARF-1 and flow cytometry. Cytometry 1991; 12: 127–132
  • Wieder E. D., Hang H., Fox M. H. Measurement of intracellular pH using flow cytometry with carboxy-SNARF-1. Cytometry 1993; 14: 916–921
  • Zhuang Y. X., Cragoe E. J., Jr., Shaikewitz T., Glaser L., Cassel D. Characterization of potent Na/Hexchange inhibitors from the amiloride series in A431 cells. Biochemistry 1984; 23: 4481–4488

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.