16
Views
6
CrossRef citations to date
0
Altmetric
Original Article

Reduction of etoposide induced cell killing by hyperthermia can occur without changes in etoposide transport or DNA topoisomerase II activity

, &
Pages 551-567 | Received 22 Jun 1995, Accepted 04 Mar 1996, Published online: 09 Jul 2009

References

  • Armour E. P., McEachern D., Wang Z., Corry P., Martinez A. Sensitivity of human cells to mild hyperthermia. Cancer Research 1993; 53: 2740–2744
  • Barlogie B., Corry P. M., Drewinko B. In vitro thermochemotherapy of human colon cancer cells with cis-dichlorodiammine platinum (II) and mitomycin C. Cancer Research 1980; 40: 1165–1168
  • Berrios M., Osheroff N., Fisher P. A. In situ localization of DNA topoisomerase II, a major polypeptide component of the Drosophilia nuclear matrix fraction. Proceedings of the National Academy of Sciences, USA 1985; 82: 4142–4146
  • Bichay T. J., Feeley M. M., Raaphorst G. P. A comparison of heat sensitivity, radiosensitivity and PLDR in four human melanoma cell lines. Melanoma Research 1992; 2: 63–69
  • Brill S. J., Dinardo S., Voelkel-Meinan K., Sternglanz R. Need for DNA topoisomerase activity as a swivel for DNA replication for transcription of ribosomal RNA. Nature 1987; 326: 414–416
  • Chen M., Beck W. T. Teniposide-resistant CEM cells, which express mutant DNA topoisomerase IIα, when treated with non-complex-stabilizing inhibitors of the enzyme, display no cross-resistance and reveal aberrant functions of the mutant enzyme. Cancer Research 1993; 53: 5946–5953
  • De Jong S., Kooistra A. J., van Vries E. G. E., Mulder N. H., et al. Topoisomerase II as a target of VM-26 and 4′-(9-acridinylamino) methanesulfon-maniside in atypical multidrug resistant human small cell lung carcinoma cells. Cancer Research 1993; 53: 1064–1071
  • Dewhirst M. Future directions in hyperthermic biology. International Journal of Hyperthermia 1994; 10: 339–345
  • Dinardo S., Voelkel K., Sternglanz R. DNA topoisomerase II mutant of Saccharomyces cerevisiae: topoisomerase II is required for segregation of daughter molecules at the termination of DNA replication. Proceedings of the National Academy of Sciences, USA 1984; 81: 2616–2620
  • Dynlacht J. R., Wong R. S. L., Albright N., Dewey W. C. Hyperthermia can reduce cytotoxicity from etoposide without a corresponding reduction in the number of topoisomerase II-DNA cleavable complexes. Cancer Research 1994; 54: 4129–4137
  • Earnshaw W. C., Halligan B., Cooke C. A., Heck M. M. Toposisomerase II is a structural component of mitotic chromosome scaffolds. Journal of Cell Biology, 100: 1706–1715
  • Eppelbaum R., Teicher B. A., Holden S. A., Ara G., Varshney A., Herman T. S. Interaction of D, L-and D-tetraplatin with hyperthermia in vitro an in vivo. European Journal of Cancer 1992; 28: 794–800
  • Fisher G., Hahn G. M. Enhancement of cis-platinum (II) diamminechloride cytotoxicity by hyperthermia. National Cancer Inst. Monographs 1982; 61: 255–257
  • Gasser S. M., Laemmli U. K. Cohabitation of scaffold binding regions with upstream/enhancer elements of three developmentally regulated genes of D. Melanogaster. Cell 1986; 46: 521–530
  • Giocanti N., Hennequin C., Balosso J., Mahler M., et al. DNA repair and cell cycle interactions in radiation sensitization by the topoisomerase II poison etoposide. Cancer Research 1993; 53: 2105–2111
  • Goswami P. C., Hill M., Higashikubo R., Wright W. D., Roti J. L. The suppression of the synthesis of a nuclear protein in cells blocked in G2 phase: identification of NP-170 as topoisomerase II. Radiation Research 1992; 132: 162–167
  • Hahn G. M., Braun J., Har-Kedar I. Thermochemotherapy: synergism between hyperthermia (42–43°C) and adriamycin (or bleomycin) in mammalian cell inactivation. Proceedings National Academy of Sciences, USA 1975; 72: 937–940
  • Hahn G. M., Li G. C. Interactions of hyperthermia and drugs: treatments and probes. National Cancer Institute of Monographs 1982; 61: 317–323
  • Hall E. J. Radiobiology for the Radiologist, Ed. 4. Lippencott Co. 1994
  • Heck M. M. S., Hittelman W. N., Earnshaw W. C. Differential expression of DNA topoisomerase I and II during the eukaryotic cell cycle. PNAS, USA 1988; 85: 1086–1090
  • Herman T. S. Temperature dependence of adriamycin, cis-diammine-dichloroplatinum, bleomycin and BCN in vitro. Cancer Research 1983; 43: 517–520
  • Hochhauser D., Harris A. L. The laboratory-clinic interface. The role of topoisomerase II α and β in drug resistance. Cancer Treatment Reviews 1993; 19: 181–194
  • Hsiang Y., Liu L. F. Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug campthothecin. Cancer Research 1988; 48: 1722–1726
  • Kalwinsky D. K., Look A. T., Duncore J., Fridland A. Effects of epipodophyllotoxin VP16–213 on cell cycle traverse, DNA synthesis and DNA strand size in cultures of human leukemic lymphoblasts. Cancer Research 1983; 43: 1592–1597
  • Kampinga H. H., Van Den Krick G., Konings A. W. Reduced DNA break formation and cytotoxicity of the toposomerase II drug 4-(9′-acridinylamino) methanesulfon-m-anisidide when combined with hyperthermia in human and rodent cell lines. Cancer Research 1989; 49: 1712–1717
  • Kampinga H. H. Hyperthermia, thermotolerance and topoisomerase II inhibitors. British Journal of Cancer 1995; 72: 333–338
  • Kroll D. J., Borgert C. J., Weidmann T. W., Rowe T. C. Drug sensitivity of heat-resistant mouse B16 melanoma variants. Radiation Research 1990; 124: 15–21
  • Kubota N., Ketehi M., Inada T. Hyperthermic enhancement of cell killing by five platinum complexes in human melanoma cells grown as monolayer cultures and multicellular spheroids. International Journal of Radiation Oncology Biology and Physics 1993; 25: 491–497
  • Lepock J. Involvement of membranes in cellular responses to hyperthermia. Radiation Research 1982; 92: 433–438
  • Liu L. F. Topoisomerase poisons as antitumor drugs. Annual Reviews in Biochemistry 1989; 58: 351–375
  • Lorico A., Rappa G., Sartorelli A. C. Novobiocin-induced accumulation of etoposide (VP-16) in WEHI-3B D+ leukemia cells. International Journal of Cancer 1992; 52: 903–909
  • Mackey M. A., Anolik S. L., Roti J. L. Cellular mechanisms associated with the lack of chronic thermotolerance expression in Hela S3 cells. Cancer Research 1992; 52: 1101–1106
  • Mackey M. A., Dewey W. C. Cell cycle progression during chronic hyperthermia in S phase CHO cells. International Journal of Hyperthermia 1989; 5: 405–413
  • Matsuo K., Kohno K., Satao S., Uchiumi K. T., Tanimura H., Yamada Y., Kuwano M. Enhanced expression of DNA topoisomerase II gene in response to heat shock stress in human epidermoid cancer KB cells. Cancer Research 1993; 53: 1085–1090
  • Mirski S. E. L., Evans C. D., Almquist K. C., Slovak M. L., Cole S. P. C. Altered topoisomerase IIα in a drug resistant small cell lung cancer line selected in VP16. Cancer Research 1993; 53: 4866–4873
  • Musk S. R. R., Steel G. G. The inhibition of cellular recovery in human tumour cells by inhibitors of topoisomerase. British Journal of Cancer 1990; 62: 364–367
  • Ng C. E., Bussey A. M., Raaphorst G. P. Inhibition of potentially lethal and sublethal damage repair by camptothecin and etoposide in human melanoma cell lines. International Journal of Radiation Biology 1994; 66: 49–57
  • Ng C. E., Bussey A. M., MacDonald H. A., Heller D. P., Wilkins D. E., Raaphorst G. P. Cross sensitivity to x-radiation and type I and II DNA topoisomerase inhibitors in a range of human and rodent cell lines. International Journal of Oncology 1995; 7: 1179–1184
  • Ng C. E., Bussey A. M., Raaphorst G. P. Sequence of treatment is important in the modification of camptothecin induced cell killing by hyperthermia. International Journal Hyperthermia 1996; 12
  • Pommier Y. DNA topoisomase I and II in cancer chemotherapy: update and perspectives. Cancer chemotherapy and Pharmacology 1993; 32: 103–108
  • Pommier Y., Leteutre F., Fesen M. R., Fujimori A., Bertrand R., Solary E., et al. Cellular determinants of sensitivity and resistance to DNA topoisomerase inhibitors. Cancer Investigations 1994; 12: 530–542
  • Raaphorst G. P., Feeley M. M., Chu G. L., Dewey W. C. A comparison of the effect of hyperthermia on DNA polymerase in hamster and human glioma cells. International Journal of Hyperthermia 1993; 9: 303–312
  • Rappa G., Lorico A., Sartorelli A. C. Reversal of etoposide resistance in non-P- glycoprotein expressing multidrug resistant tumour cell lines by novobiocin. Cancer Research 1993; 53: 5487–5493
  • Read R. A., Fox M. H., Bedford J. S. The cell cycle dependence of thermotolerance II. CHO cells heated at 45·0°C. Radiation Research 1984; 98: 491–505
  • Ritke M. K., Roberts D., Allan W. P., Raymond J., et al. Altered stability of etoposide-induced topoisomerase II DNA complexes in resistant human leukemia K562 cells. British Journal of Cancer 1994; 69: 687–697
  • Roberge M., Thing J., Hamaguchi J., Bradbury E. M. The topoisomerase II inhibitor VM-26 induced marked changes in histone HI kinase activity, histones HI and H3 phosphorylation and chromosome condensation in G2 and mitotic BHK cells. Journal of Cell Biology 1990; 111: 1753–1762
  • Sapareto S. A., Hopwood L. E., Dewey W. C., Faju M. R., Gray J. W. Effect of hyperthermia on survival and progression of CHO cells. Cancer Research 1978; 38: 393–400
  • Schneider E., Horton J. K., Yang C. H., Nakagawa M., et al. Mulitdrug resistance-associated protein gene overexpression and reduced drug sensitivity of topoisomerase II in a human breast carcinoma MCF7 cell line selected for etoposide resistance. Cancer Research 1994; 54: 152–158
  • Slichenmyer W. J., Rowinsky E. K., Donehower R. C., Kaufman S. H. The current status of camptothecin analogues as antitumor agents. JNCI 1993; 85: 271–291
  • Smith P. J., Anderson C. O., Watson J. V. Predominant role for DNA damage in etoposide-induced cytotoxicity and cell cycle perturbation in human SV40-transformed fibroblasts. Cancer Research 1986; 46: 5641–5445
  • Sullivan D. M., Glisson B. S., Hodges P. K., Smallwood-Kentzo S., Ross W. E. Proliferation dependence of topoisomerase II mediated drug action. Biochemistry 1986; 25: 2248–2256
  • Takano H., Kohno K., Ono M., Uchida Y., Kuwano M. Increased phophorylation of DNA topisomerase II in etoposide resistant mutants of human cancer KB cells. Cancer Research 1991; 51: 3951–3957
  • Toffoli G., Bevilacqua C., Franchechin A., Boiocchi M. Effect of hyperthermia on intracellular drug accumulation and chemosensitivity in drug-sensitive and drugresistant P388 leukemia cell lines. International Journal of Hyperthermia 1989; 5: 163–172
  • Trask D. K., Didonato J. A., Mueller M. T. Rapid detection and isolation and covalent DNA/protein complexes: application to topoisomerase I and II. EMBO 1984; 3: 671–676
  • Uemura T., Ohkura H., Adachi Y., Morino K., Shiozaki K., Yanagida M. DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe. Cell 1987; 50: 917–925
  • Urano M., Kahn J., Kenton L. A. Effect of bleomycin on murine tumor cells at elevated temperatures and two different pH values. Cancer Research 1988; 48: 615–619
  • Warters R. L., Barrows L. R. The heat sensitivity of HeLa S3 cell DNA topoisomerase II. Journal of Cell Physiology 1994; 159: 468–474
  • Warters R. L., Brizgys L. M. Effects of topoisomerase II inhibitors on hyperthermic cytotoxicity. Cancer Research 1988; 48: 3932–3938
  • Woesnner R. D., Mattern M. R., Mirabelli C. K., Johnson R. K., Drake F. H. Proliferation and cell-cycle dependent differences in expressions of the 170 kilodalton and 180 kilodalton forms of topoisomerase II in NIH-3T3 cells. Cell Growth and Differentiation 1991; 2: 209–214
  • Yang C. J., Horton J. K., Cowan K. H., Schneider E. Cross resistance to camptothecin analogues in a mitoxantrone-resistant human breast carcinoma cell line is not due to DNA topoisomerase I alterations. Cancer Research 1995; 55: 4004–4009

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.