References
- Okamoto K, Okazawa H, Okuda A, . A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells. Cell 1990;60:461–72.
- Scholer HR, Dressler GR, Balling R, . Oct-4: a germline-specific transcription factor mapping to the mouse t-complex. EMBO J 1990;9:2185–95.
- Scholer HR, Ruppert S, Suzuki N, . New type of POU domain in germ line-specific protein Oct-4. Nature 1990;344:435–9.
- Nichols J, Zevnik B, Anastassiadis K, . Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 1998;95:379–91.
- Niwa H, Miyazaki J, Smith AG. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet 2000;24:372–6.
- Okita K, Ichisaka T, Yamanaka S. Generation of germline-competent induced pluripotent stem cells. Nature 2007;448:313–17.
- Nakagawa M, Koyanagi M, Tanabe K, . Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol 2008;26:101–6.
- Wernig M, Meissner A, Cassady JP, . c-Myc is dispensable for direct reprogramming of mouse fibroblasts. Cell Stem Cell 2008;2:10–12.
- Yu J, Vodyanik MA, Smuga-Otto K, . Induced pluripotent stem cell lines derived from human somatic cells. Science 2007;318:1917–20.
- Saigusa S, Tanaka K, Toiyama Y, . Correlation of CD133, OCT4, and SOX2 in rectal cancer and their association with distant recurrence after chemoradiotherapy. Ann Surg Oncol 2009;16:3488–98.
- Chen Z, Xu WR, Qian H, . Oct4, a novel marker for human gastric cancer. J Surg Oncol 2009;99:414–19.
- Karoubi G, Gugger M, Schmid R, . OCT4 expression in human non-small cell lung cancer: implications for therapeutic intervention. Interact Cardiovasc Thorac Surg 2009;8:393–7.
- Du Z, Jia D, Liu S, . Oct4 is expressed in human gliomas and promotes colony formation in glioma cells. Glia 2009;57: 724–33.
- Matsutani M, Sano K, Takakura K, . Primary intracranial germ cell tumors: a clinical analysis of 153 histologically verified cases. J Neurosurg 1997;86:446–55.
- Schoenhals M, Kassambara A, De Vos J, . Embryonic stem cell markers expression in cancers. Biochem Biophys Res Commun 2009;383:157–62.
- Gidekel S, Pizov G, Bergman Y, . Oct-3/4 is a dose-dependent oncogenic fate determinant. Cancer Cell 2003;4:361–70.
- Hattab EM, Tu PH, Wilson JD, . OCT4 immunohistochemistry is superior to placental alkaline phosphatase (PLAP) in the diagnosis of central nervous system germinoma. Am J Surg Pathol 2005;29:368–71.
- Takei H, Bhattacharjee MB, Rivera A, . New immunohistochemical markers in the evaluation of central nervous system tumors: a review of 7 selected adult and pediatric brain tumors. Arch Pathol Lab Med 2007;131:234–41.
- Ngan KW, Jung SM, Lee LY, . Immunohistochemical expression of OCT4 in primary central nervous system germ cell tumours. J Clin Neurosci 2008;15:149–52.
- Santagata S, Hornick JL, Ligon KL. Comparative analysis of germ cell transcription factors in CNS germinoma reveals diagnostic utility of NANOG. Am J Surg Pathol 2006;30:1613–18.
- Kanamori M, Kumabe T, Saito R, . Optimal treatment strategy for intracranial germ cell tumors: a single institution analysis. J Neurosurg Pediatr 2009;4:506–14.
- Remmele W, Schicketanz KH. Immunohistochemical determination of estrogen and progesterone receptor content in human breast cancer. Computer-assisted image analysis (QIC score) vs. subjective grading (IRS). Pathol Res Pract 1993;189: 862–6.
- Soslow RA, Dannenberg AJ, Rush D, . COX-2 is expressed in human pulmonary, colonic, and mammary tumors. Cancer 2000;89:2637–45.
- Looijenga LH, Stoop H, de Leeuw HP, . POU5F1 (OCT3/4) identifies cells with pluripotent potential in human germ cell tumors. Cancer Res 2003;63:2244–50.
- de Jong J, Stoop H, Dohle GR, . Diagnostic value of OCT3/4 for pre-invasive and invasive testicular germ cell tumours. J Pathol 2005;206:242–9.
- Guo Y, Mantel C, Hromas RA, . Oct-4 is critical for survival/antiapoptosis of murine embryonic stem cells subjected to stress: effects associated with Stat3/survivin. Stem Cells 2008;26:30–4.
- Hu T, Liu S, Breiter DR, . Octamer 4 small interfering RNA results in cancer stem cell-like cell apoptosis. Cancer Res 2008;68:6533–40.
- Kehler J, Tolkunova E, Koschorz B, . Oct4 is required for primordial germ cell survival. EMBO Rep 2004;5:1078–83.
- Trosko JE, Tai MH. Adult stem cell theory of the multi-stage, multi-mechanism theory of carcinogenesis: role of inflammation on the promotion of initiated stem cells. Contrib Microbiol 2006;13:45–65.
- Inamura T, Nishio S, Ikezaki K, . Human chorionic gonadotrophin in CSF, not serum, predicts outcome in germinoma. J Neurol Neurosurg Psychiatry 1999;66:654–7.
- Shibamoto Y, Takahashi M, Sasai K. Prognosis of intracranial germinoma with syncytiotrophoblastic giant cells treated by radiation therapy. Int J Radiat Oncol Biol Phys 1997;37:505–10.
- Kawabata Y, Takahashi JA, Arakawa Y, . Long term outcomes in patients with intracranial germinomas: a single institution experience of irradiation with or without chemotherapy. J Neurooncol 2008;88:161–7.
- Bamberg M, Kortmann RD, Calaminus G, . Radiation therapy for intracranial germinoma: results of the German cooperative prospective trials MAKEI 83/86/89. J Clin Oncol 1999;17:2585–92.
- Merchant TE, Sherwood SH, Mulhern RK, . CNS germinoma: disease control and long-term functional outcome for 12 children treated with craniospinal irradiation. Int J Radiat Oncol Biol Phys 2000;46:1171–76.
- Shim KW, Kim TG, Suh CO, . Treatment failure in intracranial primary germinomas. Childs Nerv Syst 2007;23:1155–61.
- Xiao Qi Wang WMO, Lin Chen. Oct4 mediates chemotherapeutic drug resistance in liver cancer cells through potential Oct4-AKT-ABCG2 pathway. Hepatology Published Online Mar 26 2010:NA 2010.