Effects of PTEN inhibition on the regulation of Tau phosphorylation in rat cortical neuronal injury after oxygen and glucose deprivation

References

• Guo MF, Yu JZ, Ma CG. Mechanisms related to neuron injury and death in cerebral hypoxic ischaemia. Folia Neuropathologica 2011;49:78–87.
   Google Scholar
• Lazarovici P, Cohen G, Arien–Zakay H, Chen J, Zhang C, Chopp M, Jiang H. Multimodal neuroprotection induced by PACAP38 in oxygen-glucose deprivation and middle cerebral artery occlusion stroke models. Journal of Molecular Neuroscience 2012;48:526–540.
   PubMed Web of Science ®Google Scholar
• Zhao J, Qu Y, Wu J, Cao M, Ferriero DM, Zhang L, Mu D. PTEN inhibition prevents rat cortical neuron injury after hypoxia-ischemia. Neuroscience 2013;238:242–251.
   PubMed Web of Science ®Google Scholar
• Morgan BL, Chao CR. The effects of hypoxia on growth cones in the ovine fetal brain. Journal of Maternal-Fetal & Neonatal Medicine 2004;16:55–59.
   PubMedGoogle Scholar
• Xiong T, Tang J, Zhao J, Chen H, Zhao F, Li J, Qu Y, Ferriero D, Mu D. Involvement of the Akt/GSK-3β/CRMP-2 pathway in axonal injury after hypoxic-ischemic brain damage in neonatal rat. Neuroscience 2012;216:123–132.
   PubMed Web of Science ®Google Scholar
• Takashima A. Tauopathies and tau oligomers. Journal of Alzheimers Disease 2013;37:565–568.
   PubMed Web of Science ®Google Scholar
• Hashiguchi M, Hashiguchi T. Kinase-kinase interaction and modulation of tau phosphorylation. International Review of Cellular & Molecular Biology 2013;300:121–160.
   PubMed Web of Science ®Google Scholar
• Jayapalan S, Natarajan J. The role of CDK5 and GSK3B kinases in hyperphosphorylation of microtubule associated protein tau (MAPT) in Alzheimer’s disease. Bioinformation 2013;9:1023–1030.
   PubMedGoogle Scholar
• Song MS, Salmena L, Pandolfi PP. The functions and regulation of the PTEN tumor suppressor. Nature Reviews Molecular & Cellular Biology 2012;13:283–296.
   PubMed Web of Science ®Google Scholar
• Kitagishi Y, Matsuda S. Diets involved in PPAR and PI3K/AKT/PTEN pathway may contribute to neuroprotection in a traumatic brain injury. Alzheimers Research Therapy 2013;5:42.
   PubMed Web of Science ®Google Scholar
• Sperow M, Berry RB, Bayazitov IT, Zhu G, Baker SJ, Zakharenko SS. Phosphatase and tensin homologue (PTEN) regulates synaptic plasticity independently of its effect on neuronal morphology and migration. Journal of Physiology 2012;590:777–792.
   PubMed Web of Science ®Google Scholar
• Li D, Qu Y, Mao M, Zhang X, Li J, Ferriero D, Mu D. Involvement of the PTEN-AKT-FOXO3a pathway in neuronal apoptosis in developing rat brain after hypoxia-ischemia. Journal of Cerebral Blood Flow & Metabolism 2009;29:1903–1913.
   PubMed Web of Science ®Google Scholar
• Jiang H, Guo W, Liang X, Rao Y. Both the establishment and the maintenance of neuronal polarity require active mechanisms: critical roles of GSK-3beta and its upstream regulators. Cell 2005;120:123–135.
   PubMed Web of Science ®Google Scholar
• Zhao H, Sapolsky RM, Steinberg GK. Phosphoinositide-3-kinase/akt survival signal pathways are implicated in neuronal survival after stroke. Molecular Neurobiology 2006;34:249–270.
   PubMed Web of Science ®Google Scholar
• Chen ZL, Haegeli V, Yu H, Strickland S. Cortical deficiency of laminin gamma1 impairs the AKT/GSK-3beta signaling pathway and leads to defects in neurite outgrowth and neuronal migration. Developmental Biology 2009;327:158–168.
   PubMed Web of Science ®Google Scholar
• Kawakami F, Shimada N, Ohta E, Kagiya G, Kawashima R, Maekawa T, Maruyama H, Ichikawa T. Leucine-rich repeat kinase 2 regulates tau phosphorylation through direct activation of glycogen synthase kinase-3β. FEBS Journal 2014;281:3–13.
   PubMed Web of Science ®Google Scholar
• Randall J, Mörtberg E, Provuncher GK, Fournier DR, Duffy DC, Rubertsson S, Blennow K, Zetterberg H, Wilson DH. Tau proteins in serum predict neurological outcome after hypoxic brain injury from cardiac arrest: results of a pilot study. Resuscitation 2103;84:351–356.
   Google Scholar
• Gusdon AM, Chu CT. To eat or not to eat: neuronal metabolism, mitophagy, and Parkinson’s disease. Antioxidants & Redox Signaling 2011;14:1979–1987.
   PubMed Web of Science ®Google Scholar
• Wang G, Jiang X, Pu H, Zhang W, An C, Hu X, Liou AK, Leak RK, Gao Y, Chen J. Scriptaid, a novel histone deacetylase inhibitor, protects against traumatic brain injury via modulation of PTEN and AKT pathway: scriptaid protects against TBI via AKT. Neurotherapeutics 2013;10:124–142.
   PubMed Web of Science ®Google Scholar
• Liu K, Lu Y, Lee JK, Samara R, Willenberg R, Sears-Kraxberger I, Tedeschi A, Park KK, Jin D, Cai B, et al. PTEN deletion enhances the regenerative ability of adult corticospinal neurons. Nature Neuroscience 2010;13:1075–1081.
   PubMed Web of Science ®Google Scholar
• Shi GD, OuYang YP, Shi JG, Liu Y, Yuan W, Jia LS. PTEN deletion prevents ischemic brain injury by activating the mTOR signaling pathway. Biochemical & Biophysical Research Communications 2011;404:941–945.
   PubMed Web of Science ®Google Scholar
• Chen Z, Chen B, Xu WF, Liu RF, Yang J, Yu CX. Effects of PTEN inhibition on regulation of tau phosphorylation in an okadaic acid-induced neurodegeneration model. International Journal of Developmental Neuroscience 2012;30:411–419.
   PubMed Web of Science ®Google Scholar
• Nakanishi A, Wada Y, Kitagishi Y, Matsuda S. Link between PI3K/AKT/PTEN Pathway and NOX Proteinin Diseases. Aging & Disease 2014;5:203–211.
   PubMed Web of Science ®Google Scholar
• Kyrylenko S, Roschier M, Korhonen P, Salminen A. Regulation of PTEN expression in neuronal apoptosis. Brain Research Molecular Brain Research 1999;73:198–202.
   PubMedGoogle Scholar
• Zhao H, Shimohata T, Wang JQ, Sun G, Schaal DW, Sapolsky RM, Steinberg GK. Akt contributes to neuroprotection by hypothermia against cerebral ischemia in rats. Journal of Neuroscience 2005;25:9794–9806.
   PubMed Web of Science ®Google Scholar
• Schmid AC, Byrne RD, Vilar R, Woscholski R. Bisperoxovanadium compounds are potent PTEN inhibitors. FEBS Letters 2004;566:35–38.
   PubMed Web of Science ®Google Scholar
• Rickle A, Behbahani H, Ankarcrona M, Winblad B, Cowburn RF. PTEN, Akt, and GSK3beta signalling in rat primary cortical neuronal cultures following tumor necrosis factor-alpha and trans-4-hydroxy-2-nonenal treatments. Journal of Neuroscience Research 2006;84:596–605.
   PubMed Web of Science ®Google Scholar
• Guo JY, Ding J, Yuan F, Chen H, Chen SW, Tian HL. Dose-dependent protective effect of bisperoxovanadium against acute cerebral ischemia in a rat model of ischemia/reperfusion injury. International Journal of Molecular Science 2013;14:12013–12022.
   PubMed Web of Science ®Google Scholar
• Jayapalan S, Natarajan J. The role of CDK5 and GSK3B kinases in hyperphosphorylation of microtubule associated protein tau (MAPT) in Alzheimer’s disease. Bioinformation 2013;9:1023–1030.
   PubMedGoogle Scholar
• Dong DW, Zhang YS, Yang WY, Wang-Qin RQ, Xu AD, Ruan YW. Hyperphosphorylation of tau protein in the ipsilateral thalamus after focal cortical infarction in rats. Brain Research 2014;1543:280–289.
   PubMed Web of Science ®Google Scholar
• Iqbal K, Gong CX, Liu F. Hyperphosphorylation-induced tau oligomers. Frontier in Neurology 2013;4:112–120.
   PubMed Web of Science ®Google Scholar
• Cantley LC, Neel BG. New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway. Proceedings of the National Academy of Science USA 1999;96:4240–4245.
   Google Scholar
• Yoshimura T, Kawano Y, Arimura N, Kawabata S, Kikuchi A, Kaibuchi K. GSK-3beta regulates phosphorylation of CRMP-2 and neuronal polarity. Cell 2005;120:137–149.
   PubMed Web of Science ®Google Scholar
• Kerr F, Rickle A, Nayeem N, Brandner S, Cowburn RF, Lovestone S. PTEN, a negative regulator of PI3 kinase signaling, alters tau phosphorylation in cells by mechanisms independent of GSK-3. FEBS Letters 2006;580:3121–3128.
   PubMed Web of Science ®Google Scholar
• Ding VW, Chen RH, McCormick F. Differential regulation of glycogen synthase kinase 3beta by insulin and Wnt signaling. Journal of Biological Chemistry 2000;275:32475–32481.
   PubMed Web of Science ®Google Scholar
• Hetman M, Kanning K, Cavanaugh JE, Xia Z. Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase. Journal of Biological Chemistry 1999;274:22569–22580.
   PubMed Web of Science ®Google Scholar
• Crowder RJ, Freeman RS. Glycogen synthase kinase-3 beta activity is critical for neuronal death caused by inhibiting phosphatidylinositol 3-kinase or Akt but not for death caused by nerve growth factor withdrawal. Journal of Biological Chemistry 2000;275:34266–34271.
   PubMed Web of Science ®Google Scholar