The Effect of Adjuvant Dimethylenastron, a Mitotic Kinesin Eg5 Inhibitor, in Experimental Glaucoma Filtration Surgery

REFERENCES

• The Advanced Glaucoma Intervention Study (AGIS):7. The relationship between control of intraocular pressure and visual field deterioration. The AGIS Investigators. Am J Ophthalmol. 2000;130:429–440.
   PubMed Web of Science ®Google Scholar
• Cordeiro MF, Chang L, Lim KS, et al. Modulating conjunctival wound healing. Eye. 2000;14:536–547.
   PubMedGoogle Scholar
• Khaw PT, Occleston NL, Schultz G, et al. Activation and suppression of fibroblast function. Eye. 1994;2:188–195.
   Google Scholar
• Khaw PT, Doyle JW, Sherwood MB, et al. Effects of intraoperative 5-fluorouracil or mitomycin C on glaucoma filtration surgery in the rabbit. Ophthalmology. 1993;100:367–372.
   PubMed Web of Science ®Google Scholar
• Lu DW, Chang CJ, Chiang CH, et al. Wound modulation after trabeculectomy by different formulations of antimetabolites in rabbits. J Ocul Pharmacol Ther. 2000;16:529–538.
   Google Scholar
• Doyle JW, Sherwood MB, Khaw PT, et al. Intraoperative 5-fluorouracil for filtration surgery in the rabbit. Invest Ophthalmol Vis Sci. 1993;34:3313–3319.
   PubMed Web of Science ®Google Scholar
• Jampel HD, Pasquale LR, Dibernard C. Hypotony maculopathy following trabeculectomy with mitomycin C. Arch Ophthalmol. 1992;110:1049–1050.
   PubMedGoogle Scholar
• Parrish R, Minkler D. “Late endophthalmitis”: Filtering surgery time bomb? Ophthalmology. 1996;103:1167–1168.
   Google Scholar
• Stamper RL, McMenemy MG, Lieberman MF. Hypotonus maculopathy after trabeculectomy with subconjunctival 5-fluorouracil. Am J Ophthalmol. 1992;114:544–553.
   PubMed Web of Science ®Google Scholar
• Gartner M, Sunder-Plassmann N, Seiler J, et al. Development and biological evaluation of potent and specific inhibitors of mitotic kinesin Eg5. Chembiochem. 2005;6:1173–1177.
   PubMed Web of Science ®Google Scholar
• Rello-Varona S, Vitale I, Kepp O, et al. Preferential killing of tetraploid tumor cells by targeting the mitotic kinesin Eg5. Cell Cycle. 2009;8:1030–1035.
   PubMed Web of Science ®Google Scholar
• Liu M, Yu H, Huo L, et al. Validating the mitotic kinesin Eg5 as a therapeutic target in pancreatic cancer cells and tumor xenografts using a specific inhibitor. Biochem Pharmacol. 2008;76:169–178.
   Google Scholar
• Wong TT, Mead AL, Khaw PT. Matrix metalloproteinase inhibition modulates postoperative scarring after experimental glaucoma filtration surgery. Invest Ophthalmol Vis Sci. 2003;44:1097–1103.
   PubMed Web of Science ®Google Scholar
• Cantor LB, Mantravadi A, WuDunn D, et al. Morphologic classification of filtering blebs after glaucoma filtration surgery: The Indiana Bleb Appearance Grading Scale. J Glaucoma. 2003;12:266–271.
   PubMed Web of Science ®Google Scholar
• Khaw PT, Chang L, Wong TT, et al. Modulation of wound healing after glaucoma surgery. Curr Opin Ophthalmol. 2001;12:143–148.
   PubMed Web of Science ®Google Scholar
• Allen LE, Manuchehri K, Corridan PG. The treatment of encapsulated trabeculectomy blebs in an out-patient setting using a needling technique and subconjunctival 5-fluorouracil injection. Eye. 1998;12:119–123.
   Google Scholar
• Katz GJ, Higginbotham EJ, Lichter PR, et al. Mitomycin C versus 5-fluouracil in high-risk glaucoma filtration surgery: Extended follow-up. Ophthalmology. 1995;102:1263–1269.
   PubMed Web of Science ®Google Scholar
• Migdal C, Gregory W, Hitchings R. Long-term functional outcome after early surgery compared with laser and medicine in open angle glaucoma. Ophthalmology. 1994;101:1651–1656.
   PubMed Web of Science ®Google Scholar
• Uppal P, Jampel HD, Quigley HA, et al. Pharmacokinetics of etoposide delivery by a bioerodible drug carrier implanted at glaucoma surgery. J Ocul Pharmacol. 1994;10:471–479.
   PubMedGoogle Scholar
• Jampel HD, Koya P, Leong K, et al. In vitro release of hydrophobic drugs from polyanhydride disks. Ophthalmic Surg. 1991;22:676–680.
   Google Scholar
• Jampel HD, Thibault D, Leong KW, et al. Glaucoma filtration surgery in nonhuman primates using taxol and etoposide in polyanhydride carriers. Invest Ophthalmol Vis Sci. 1993;34:3076–3083.
   PubMed Web of Science ®Google Scholar
• Lobert S. Neurotoxicity in cancer chemotherapy: Vinca alkaloids. Crit Care Nurse. 1997;17:71–79.
   Google Scholar
• Zhou J, Giannakakou P. Targeting microtubules for cancer chemotherapy. Curr Med Chem Anti-Canc Agents. 2005;5:65–71.
   PubMedGoogle Scholar
• Rowinsky EK. The development and clinical utility of the taxane class of antimicrotubule chemotherapy agents. Annu Rev Med. 1997;48:353–374.
   PubMed Web of Science ®Google Scholar
• Sakowicz R, Finer JT, Beraud C, et al. Antitumor activity of a kinesin inhibitor. Cancer Res. 2004;64:3276–3280.
   PubMed Web of Science ®Google Scholar
• Liu M, Aneja R, Liu C, et al. Inhibition of the mitotic kinesin Eg5 up-regulates Hsp70 through the phosphatidylinositol 3-kinase/Akt pathway in multiple myeloma cells. J Biol Chem. 2006;281:18090–18097.
   PubMed Web of Science ®Google Scholar
• Picht G, Grehn F. Classification of filtering blebs in trabeculectomy: Biomicroscopy and functionality. Curr Opin Ophthalmol. 1998;9:2–8.
   PubMedGoogle Scholar
• Skuta G, Parrish R. Wound healing in glaucoma filtering surgery. Surv Ophthalmol. 1987;32:149–170.
   PubMed Web of Science ®Google Scholar
• Shingleton B. Management of the failing glaucoma filter. Ophthalmic Surg Lasers. 1996;27:445–451.
   PubMedGoogle Scholar
• Desmoulière A, Redard M, Darby I, et al. Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar. Am J Pathol. 1995;146:56–66
   PubMed Web of Science ®Google Scholar
• Grisanti S, Szurman P, Warga M, et al. Decorin modulates wound healing in experimental glaucoma filtration surgery: A pilot study. Invest Ophthalmol Vis Sci. 2005;46:191–196.
   PubMed Web of Science ®Google Scholar
• Miller MH, Grierson I, Unger WI, et al. Wound healing in an animal model of glaucoma fistulizing surgery in the rabbit. Ophthalmic Surg. 1989;20:350–357.
   PubMedGoogle Scholar
• Nakamuta M, Ohta S, Tada S, et al. Dimethyl sulfoxide inhibits dimethylnitrosamine-induced hepatic fibrosis in rats. Int J Mol Med. 2001;8:553–560.
   PubMed Web of Science ®Google Scholar