Deleterious Role of Anti-high Mobility Group Box 1 Monoclonal Antibody in Retinal Ischemia-reperfusion Injury

REFERENCES

• Tsujikawa A, Ogura Y, Hiroshiba N, Miyamoto K, Kiryu J, Honda Y. Tacrolimus (FK506) attenuates leukocyte accumulation after transient retinal ischemia. Stroke. 1998;29:1431–1437; discussion 1437–1438.
   PubMedGoogle Scholar
• Tsujikawa A, Ogura Y, Hiroshiba N, Miyamoto K, Kiryu J, Tojo SJ, Miyasaka M, Honda Y. Retinal ischemia-reperfusion injury attenuated by blocking of adhesion molecules of vascular endothelium. Invest Ophthalmol Vis Sci. 1999;40:1183–1190.
   PubMedGoogle Scholar
• Hirooka K, Miyamoto O, Jinming P, Du Y, Itano T, Baba T, Tokuda M, Shiraga F. Neuroprotective effects of D-allose against retinal ischemia-reperfusion injury. Invest Ophthalmol Vis Sci. 2006;47:1653–1657.
   PubMed Web of Science ®Google Scholar
• Iwama D, Miyamoto K, Miyahara S, Tamura H, Tsujikawa A, Yamashiro K, Kiryu J, Yoshimura N. Neuroprotective effect of cilostazol against retinal ischemic damage via inhibition of leukocyte-endothelial cell interactions. J Thromb Haemost. 2007;5:818–825.
   PubMedGoogle Scholar
• Sakamoto K, Kawakami T, Shimada M, Yamaguchi A, Kuwagata M, Saito M, Nakahara T, Ishii K. Histological protection by cilnidipine, a dual L/N-type Ca(2+) channel blocker, against neurotoxicity induced by ischemia-reperfusion in rat retina. Exp Eye Res. 2009;88:974–982.
   PubMed Web of Science ®Google Scholar
• Büchi ER. Cell death in the rat retina after a pressure-induced ischemia-reperfusion insult: An electron microscopic study. I: Ganglion cell layer and inner nuclear layer. Exp Eye Res. 1992;55:605–613.
   PubMed Web of Science ®Google Scholar
• Nitatori T, Sato N, Waguri S, Karasawa Y, Araki H, Shibanai K, Kominami E, Uchiyama Y. Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis. J Neurosci. 1995;15:1001–1011.
   PubMed Web of Science ®Google Scholar
• Rosenbaum DM, Rosenbaum PS, Gupta A, Michaelson MD, Hall DH, Kessler JA. Retinal ischemia leads to apoptosis which is ameliorated by aurintricarboxylic acid. Vision Res. 1997;37:3445–3451.
   PubMed Web of Science ®Google Scholar
• Halliwell B, Gutteridge JM. Free Radicals in Biology and Medicine. Oxford, UK: Clarendon Press; 1985.
   Google Scholar
• Goodwin GH, Sanders C, Johns EW. A new group of chromatin-associated proteins with a high content of acidic and basic amino acids. Eur J Biochem. 1973;38:14–19.
   PubMedGoogle Scholar
• Lotze MT, Tracey KJ. High-mobility group box 1 protein (HMGB1): Nuclear weapon in the immune arsenal. Nat Rev Immunol. 2005;5:331–342.
   PubMed Web of Science ®Google Scholar
• Calogero S, Grassi F, Aguzzi A, Voigtländer T, Ferrier P, Ferrari S, Bianchi ME. The lack of chromosomal protein Hmgb1 does not disrupt cell growth but causes lethal hypoglycaemia in newborn mice. Nat Genet. 1999;22:276–280.
   PubMed Web of Science ®Google Scholar
• Hoppe G, Rayborn ME, Sears JE. Diurnal rhythm of the chromatin protein Hmgb1 in rat photoreceptors is under circadian regulation. J Comp Neurol. 2007;501:219–230.
   PubMed Web of Science ®Google Scholar
• Goldstein RS, Gallowitsch-Puerta M, Yang L, Rosas-Ballina M, Huston JM, Czura CJ, Lee DC, Ward MF, Bruchfeld AN. Elevated high-mobility group box 1 levels in patients with cerebral and myocardial ischemia. Shock. 2006;25:571–574.
   PubMed Web of Science ®Google Scholar
• Kim JB, Sig Choi J, Yu YM, Nam K, Piao CS, Kim SW, Lee MH, Han PL, Park JS, Leem JK. HMGB1, a novel cytokine-like mediator linking acute neuronal death and delayed neuroinflammation in the postischemic brain. J Neurosci. 2006;26:6413– 6421.
   PubMed Web of Science ®Google Scholar
• Faraco G, Fossati S, Bianchi ME, Patrone M, Pedrazzi M, Sparator B. Moroni F, Chiarugi A. High mobility group box 1 protein is released by neural cells upon different stresses and worsens ischemic neurodegeneration in vitro and in vivo J Neurochem. 2007;103:590–603.
   PubMed Web of Science ®Google Scholar
• Liu K, Mori S, Takahashi HK, Tomono Y, Wake H, Kanke T, Sato Y, Hiraga N, Adachi N, Yoshino T, Nishibori M. Anti-high mobility group box 1 monoclonal antibody ameliorates brain infarction induced by transient ischemia in rats. FASEB J. 2007;21:3904–3916.
   PubMed Web of Science ®Google Scholar
• Kim JB, Lim CM, Yu YK, Lee JK. Induction and subcellular localization of high-mobility group box-1 (HMGB1) in the postischemic rat brain. J Neurosci Res. 2008;86:1125–1131.
   PubMed Web of Science ®Google Scholar
• Muhammad S, Barakat W, Stoyanov S, Murikinati S, Yang H, Tracey KJ, Bendszus M, Rossetti G., Nawroth PP, Bierhaus A, Schwaninger M. The HMGB1 receptor RAGE mediates ischemic brain damage. J Neurosci. 2008;28:12023–12031.
   PubMed Web of Science ®Google Scholar
• Qiu J, Nishimura M, Wang Y, Sims JR, Qiu S, Savitz SI, Salamone S, Moskowitz MA. Early release of HMGB-1 from neurons after the onset of brain ischemia. J Cereb Blood Flow Metab. 2008;28:927–938.
   PubMed Web of Science ®Google Scholar
• Pedrazzi M, Raiteri L, Bonanno G, et al. Stimulation of excitatory amino acid release from adult mouse brain glia subcellular particles by high mobility group box 1 protein. J Neurochem 2006;99:827–838.
   PubMed Web of Science ®Google Scholar
• OozawaS Mori, S, Kanke T, Takahashi H, Liu K, Tomono Y, Asanima M, Miyazaki I, Nishibori M, Sano S. Effect of HMGB1 on ischemia-reperfusion injury in the rat heart. Circ J. 2008;72:1178–1184.
   Google Scholar
• Louzada-Junior P, Dias JJ, Santos WF, Lachat JJ, Bradford HF, Coutinho-Netto J. Glutamate release in experimental ischaemia of the retina: An approach using microdialysis. J Neurochem. 1992;59:358–363.
   PubMed Web of Science ®Google Scholar
• Adachi K, Kashii S, Masai H, Ueda M, Morizane C, Kaneda K, Kume T, Akaike A, Honda Y. Mechanism of the pathogenesis of glutamate neurotoxicity in retinal ischemia. Graefes Arch Clin Exp Ophthalmol. 1998;236:766–774.
   PubMed Web of Science ®Google Scholar
• Osborne NN, Ugarte M, Chao M, Chidlow G., Bae JH, Wood JP, Nash MS. Neuroprotection in relation to retinal ischemia and relevance of glaucoma. Surv Ophthalmol. 1999;43:S102–S128.
   PubMed Web of Science ®Google Scholar
• Coleman K, Fitzgerald D, Eustace P, Bouchier-Hayes D. Electroretinography, retinal ischemia and carotid artery disease. Eur J Vasc Surg. 1990;4:569–573.
   Google Scholar
• Zager E, Ames A 3rd. Reduction of cellular energy requirements. Screening for agents that may protect against CNS ischemia. J Neurosurg. 1998;69:568–579
   Google Scholar
• Jacobson JH, Gestring GF. Centrifugal influence upon the electroretinogram. AMA Arch Ophthalmol. 1958;60:295–302.
   Google Scholar
• Noell WK. Differentiation, metabolic organization, and viability of the visual cell. AMA Arch Ophthalmol. 1958;60:702–733.
   Google Scholar
• Arimura N, KI-I Y, Hashiguchi T, Kawahara K, Biswas KK, Nakamura M, Sonoda Y, Yamakiri K, Okubo A, Sakamoto T, Maruyama I. Intraocular expression and release of high-mobility group box 1 protein in retinal detachment. Lab Invest. 2009;89: 278–289.
   PubMed Web of Science ®Google Scholar
• Watanabe T, Keino H, Sato Y, Kudo A, Kawakami H, Okada AA. High mobility group box protein-1 in experimental autoimmune uveoretinitis. Invest Ophthalmol Vis Sci. 2009;50:2283–2290.
   Google Scholar
• Scaffidi P, Misteli T, Bianchi ME. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature. 2002;418:191–195.
   PubMed Web of Science ®Google Scholar
• Büchi ER. Cell death in the rat retina after a pressure-induced ischemia-reperfusion insult: an electron microscopic study. I. ganglion cell layer and inner nuclear layer. Exp Eye Res. 1992;55:605–613.
   PubMed Web of Science ®Google Scholar