Ocular Pain After Intravitreal Injection

REFERENCES

• Ohm J. Über die Behandlung der Netzhautablösung durch operative Entleerung der subretinalen Flössigkeit und Einspritzung von Luft in den Glaskörper. Albrecht von Graefes Arch Ophthalmol 1911;79:442–450
   Google Scholar
• Harris MJ, de Bustros S, Michels RG. Treatment of retinal detachments due to macular holes. Retina 1984;4:144–147
   PubMedGoogle Scholar
• Daily MJ, Peyman GA, Fishman G. Intravitreal injection of methicillin for treatment of endophthalmitis. Am J Ophthalmol 1973;76:343–350
   PubMedGoogle Scholar
• Daikos GL, Pulido J, Kathpalia SB, Jackson GG. Intravenous and intraocular ganciclovir for CMV retinitis in patients with AIDS or chemotherapeutic immunosuppression. Br J Ophthalmol 1988;72:521–524
   PubMedGoogle Scholar
• Kaiser PK. Ranibizumab: the evidence of its therapeutic value in neovascular age-related macular degeneration. Core Evid 2008;2:273–294
   PubMedGoogle Scholar
• Amoaku W, Pearce I, Browning A. Guidelines for intravitreal injections procedure. London: The Royal College of Ophthalmologists; 2009. Available from: http://www.rcophth.ac.uk/page.asp?section=451&sectionTitle=Clinical+Guidelines [last accessed 6 Jan 2013]
   Google Scholar
• Korobelnik JF, Weber M, Cohen SY. Recommandations pour la réalisation des injections intravitréennes. J Fr Ophtalmol 2009;32:288–289
   PubMedGoogle Scholar
• Ruiz-Moreno JM, Arias-Barquet L, Armada-Maresca F, Boixadera-Espax A, García-Layana A, Gómez-Ulla-de-Irazazábal F, et al. Guidelines of clinical practice of the SERV: treatment of exudative age-related macular degeneration (AMD). Arch Soc Esp Oftalmol 2009;84:333–344
   PubMedGoogle Scholar
• Arias-Barquet L, Basauri-Rementeria E, Gomez-Ulla F, Martinez-Sanz F. Manejo de las inyecciones intravítreas. 2009. Available from: https://www.serv.es/pdf/Guia_SERV_02.pdf [last accessed 6 Jan 2013]
   Google Scholar
• Kaderli B, Avci R. Comparison of topical and subconjunctival anesthesia in intravitreal injection administrations. Eur J Ophthalmol 2006;16:718–721
   PubMed Web of Science ®Google Scholar
• Cintra LP, Lucena LR, da Silva JA, Costa RA, Scott IU, Jorge R. Comparative study of analgesic effectiveness using three different anesthetic techniques for intravitreal injection of bevacizumab. Ophthalmic Surg Lasers Imaging 2009;40:13–18
   PubMedGoogle Scholar
• Blaha GR, Tilton EP, Barouch FC, Marx JL. Randomized trial of anesthetic methods for intravitreal injections. Retina 2011;31:535–539
   PubMed Web of Science ®Google Scholar
• Rifkin L, Schaal S. Factors affecting patients’ pain intensity during in office intravitreal injection procedure. Retina 2012;32:696–700
   PubMed Web of Science ®Google Scholar
• Yau GL, Jackman CS, Hooper PL, Sheidow TG. Intravitreal injection anesthesia – comparison of different topical agents: a prospective randomized controlled trial. Am J Ophthalmol 2011;151:333–337 e2
   PubMed Web of Science ®Google Scholar
• Moisseiev E, Regenbogen M, Bartfeld Y, Barak A. Evaluation of pain in intravitreal bevacizumab injections. Curr Eye Res 2012;37:813–817
   PubMed Web of Science ®Google Scholar
• Davis MJ, Pollack JS, Shott S. Comparison of topical anesthetics for intravitreal injections: a randomized clinical trial. Retina 2012;32:701–705
   PubMed Web of Science ®Google Scholar
• Balkan BK, Iyilikci L, Gunenc F, Uzümlü H, Kara HC, Celik L, et al. Comparison of sedation requirements for cataract surgery under topical anesthesia or retrobulbar block. Eur J Ophthalmol 2004;14:473–477
   PubMedGoogle Scholar
• Zollner C, Mousa S, Klinger A, Förster M, Schäfer M. Topical fentanyl in a randomized, double-blind study in patients with corneal damage. Clin J Pain 2008;24:690–696
   PubMed Web of Science ®Google Scholar
• Kim CS, Nam KY, Kim JY. Effect of prophylactic topical brimonidine (0.15%) administration on the development of subconjunctival hemorrhage after intravitreal injection. Retina 2011;31:389–392
   PubMed Web of Science ®Google Scholar
• Ladas ID, Karagiannis DA, Rouvas AA, Kotsolis AI, Liotsou A, Vergados I. Safety of repeat intravitreal injections of bevacizumab versus ranibizumab: our experience after 2000 injections. Retina 2009;29:313–318
   PubMed Web of Science ®Google Scholar
• Horn W, Hoerauf H. Intravitreale Injektionen bei Antikoagulation. Klin Monbl Augenheilkd 2008;225:217–219
   PubMedGoogle Scholar
• Aref AA. Management of immediate and sustained intraocular pressure rise associated with intravitreal antivascular endothelial growth factor injection therapy. Curr Opin Ophthalmol 2012;23:105–110
   PubMedGoogle Scholar
• Dwinger MC, Pieper-Bodeewes I, Eter N, Holz FG. Augeninnendruck und Notwendigkeit einer Parazentese unmittelbar nach intravitrealer Triamcinolon-Injektion. Klin Monbl Augenheilkd 2005;222:638–642
   PubMedGoogle Scholar
• Wu L, Evans T. Cambios inmediatos en la presión intraocular después de una inyección intravítrea de 2,5mg de bevacizumab. Arch Soc Esp Oftalmol 2010;85:364–369
   PubMedGoogle Scholar
• Olmez G, Cakmak SS, Caca I, Unlu MK. Intraocular pressure and quality of blockade in peribulbar anesthesia using ropivacaine or lidocaine with adrenaline: a double-blind randomized study. Tohoku J Exp Med 2004;204:203–208
   PubMed Web of Science ®Google Scholar
• Ozcan AA, Ozdemir N, Gunes Y, Bozkurt A, Yagmur M, Alparslan ZN. Intraocular pressure, quality of block, and degree of pain associated with ropivacaine in peribulbar block: a comparative randomized study with bupivacaine-lidocaine mixture. Eur J Ophthalmol 2003;13:794–797
   PubMedGoogle Scholar
• Rodrigues EB, Grumann A, Jr Penha FM, Shiroma H, Rossi E, Meyer CH, et al. Effect of needle type and injection technique on pain level and vitreal reflux in intravitreal injection. J Ocul Pharmacol Ther 2011;27:197–203
   PubMed Web of Science ®Google Scholar
• de Stefano VS, Abechain JJ, de Almeida LF, Verginassi DM, Rodrigues EB, Freymuller E, et al. Experimental investigation of needles, syringes and techniques for intravitreal injections. Clin Experiment Ophthalmol 2011;39:236–242
   PubMed Web of Science ®Google Scholar
• Lorenz K, Zwiener I, Mirshahi A. Subconjunctival reflux and need for paracentesis after intravitreal injection of 0.1 ml bevacizumab: comparison between 27-gauge and 30-gauge needle. Graefes Arch Clin Exp Ophthalmol 2010;248:1573–1577
   PubMed Web of Science ®Google Scholar
• Turgut B, Demir T, Celiker U. The effects of injection site on the reflux following intravitreal injections. J Clin Med Res 2009;1:280–284
   PubMedGoogle Scholar