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Original Article

The Changes of 8-OHdG, hOGG1, APE1 and Pol β in Lenses of Patients with Age-Related Cataract

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Pages 378-385 | Received 23 Feb 2014, Accepted 01 May 2014, Published online: 09 Jun 2014

References

  • Pascolini D, Mariotti SP. Global estimates of visual impairment: 2010. Br J Ophthalmol 2012;96:614–618
  • Lu ZQ, Sun WH, Yan J, Jiang TX, Zhai SN, Li Y. Cigarette smoking, body mass index associated with the risks of age-related cataract in male patients in northeast China. Int J Ophthalmol 2012;5:317–322
  • Zhao J, Ellwein LB, Cui H, Ge J, Guan H, Lv J, et al. Prevalence of vision impairment in older adults in rural China: the China Nine-Province Survey. Ophthalmology 2010;117:409.e1–416.e1
  • Furtado JM, Lansingh VC, Carter MJ, Milanese MF, Pena BN, Ghersi HA, et al. Causes of blindness and visual impairment in Latin America. Surv Ophthalmol 2012;57:149–177
  • Wormstone IM, Wride MA. The ocular lens: a classic model for development, physiology and disease. Philos Trans R Soc Lond B Biol Sci 2011;366:1190–1192
  • Galor A, Lee DJ. Effects of smoking on ocular health. Curr Opin Ophthalmol 2011;22:477–482
  • Babizhayev MA. Biomarkers and special features of oxidative stress in the anterior segment of the eye linked to lens cataract and the trabecular meshwork injury in primary open-angle glaucoma: challenges of dual combination therapy with N-acetylcarnosine lubricant eye drops and oral formulation of nonhydrolyzed carnosine. Fundam Clin Pharmacol 2012;26:86–117
  • Michael R, Bron AJ. The ageing lens and cataract: a model of normal and pathological ageing. Philos Trans R Soc Lond B Biol Sci 2011;366:1278–1292
  • Beebe DC, Holekamp NM, Shui YB. Oxidative damage and the prevention of age-related cataracts. Ophthalmic Res 2010;44:155–165
  • Dalle-Donne I, Rossi R, Colombo R, Giustarini D, Milzani A. Biomarkers of oxidative damage in human disease. Clin Chem 2006;52:601–623
  • Wolf N, Pendergrass W, Singh N, Swisshelm K, Schwartz J. Radiation cataracts: mechanisms involved in their long delayed occurrence but then rapid progression. Mol Vis 2008;14:274–285
  • Valavanidis A, Vlachogianni T, Fiotakis C. 8-hydroxy-2'-deoxyguanosine (8-OHdG): a critical biomarker of oxidative stress and carcinogenesis. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 2009;27:120–139
  • Kisic B, Miric D, Zoric L, Ilic A, Dragojevic I. Antioxidant capacity of lenses with age-related cataract. Oxid Med Cell Longev 2012;2012:467130
  • Hazra TK, Das A, Das S, Choudhury S, Kow YW, Roy R. Oxidative DNA damage repair in mammalian cells: a new perspective. DNA Repair (Amst) 2007;6:470–480
  • Dezor M, Dorszewska J, Florczak J, Kempisty B, Jaroszewska-Kolecka J, Rozycka A, et al. Expression of 8-oxoguanine DNA glycosylase 1 (OGG1) and the level of p53 and TNF-alphalpha proteins in peripheral lymphocytes of patients with Alzheimer's disease. Folia Neuropathol 2011;49:123–131
  • Hirano T. Repair system of 7,8-dihydro-8-oxoguanine as a defense line against carcinogenesis. J Radiat Res 2008;49:329–340
  • Kim YJ, Wilson 3rd DM. Overview of base excision repair biochemistry. Curr Mol Pharmacol 2012;5:3–13
  • Zhang Y, Zhang L, Bai J, Ge H, Liu P. Expression changes in DNA repair enzymes and mitochondrial DNA damage in aging rat lens. Mol Vis 2010;16:1754–1763
  • Zhang Y, Ouyang S, Zhang L, Tang X, Song Z, Liu P. Oxygen-induced changes in mitochondrial DNA and DNA repair enzymes in aging rat lens. Mech Ageing Dev 2010;131:666–673
  • Sobol RW, Foley JF, Nyska A, Davidson MG, Wilson SH. Regulated over-expression of DNA polymerase beta mediates early onset cataract in mice. DNA Repair (Amst) 2003;2:609–622
  • Izumi T, Wiederhold LR, Roy G, Roy R, Jaiswal A, Bhakat KK, et al. Mammalian DNA base excision repair proteins: their interactions and role in repair of oxidative DNA damage. Toxicology 2003;193:43–65
  • Jiang S, Hu N, Zhou J, Zhang J, Gao R, Hu J, et al. Polymorphisms of the WRN gene and DNA damage of peripheral lymphocytes in age-related cataract in a Han Chinese population. Age (Dordr) 2013;35:2435–2444
  • Pendergrass W, Penn P, Possin D, Wolf N. Accumulation of DNA, nuclear and mitochondrial debris, and ROS at sites of age-related cortical cataract in mice. Invest Ophthalmol Vis Sci 2005;46:4661–4670
  • Ates O, Alp HH, Kocer I, Baykal O, Salman IA. Oxidative DNA damage in patients with cataract. Acta Ophthalmol 2010;88:891–895
  • Osnes-Ringen O, Azqueta AO, Moe MC, Zetterstrom C, Roger M, Nicolaissen B, et al. DNA damage in lens epithelium of cataract patients in vivo and ex vivo. Acta Ophthalmol 2013;91:652–656
  • Sorte K, Sune P, Bhake A, Shivkumar VB, Gangane N, Basak A. Quantitative assessment of DNA damage directly in lens epithelial cells from senile cataract patients. Mol Vis 2011;17:1–6
  • Zhang Y, Zhang L, Song Z, Sun DL, Liu HR, Fu SB, et al. Genetic polymorphisms in DNA repair genes OGG1, APE1, XRCC1, and XPD and the risk of age-related cataract. Ophthalmology 2012;119:900–906
  • Chylack Jr LT, Leske MC, McCarthy D, Khu P, Kashiwagi T, Sperduto R. Lens opacities classification system II (LOCS II). Arch Ophthalmol 1989;107:991–997
  • Truscott RJ. Age-related nuclear cataract-oxidation is the key. Exp Eye Res 2005;80:709–725
  • Asomugha CO, Gupta R, Srivastava OP. Identification of crystallin modifications in the human lens cortex and nucleus using laser capture microdissection and CyDye labeling. Mol Vis 2010;16:476–494
  • Pendergrass W, Zitnik G, Urfer SR, Wolf N. Age-related retention of fiber cell nuclei and nuclear fragments in the lens cortices of multiple species. Mol Vis 2011;17:2672–2684
  • Pendergrass W, Zitnik G, Tsai R, Wolf N. X-ray induced cataract is preceded by LEC loss, and coincident with accumulation of cortical DNA, and ROS; similarities with age-related cataracts. Mol Vis 2010;16:1496–1513
  • Ock CY, Kim EH, Choi DJ, Lee HJ, Hahm KB, Chung MH. 8-Hydroxydeoxyguanosine: not mere biomarker for oxidative stress, but remedy for oxidative stress-implicated gastrointestinal diseases. World J Gastroenterol 2012;18:302–308
  • Zheng T, Lu Y. Changes in SIRT1 expression and its downstream pathways in age-related cataract in humans. Curr Eye Res 2011;36:449–455
  • Andley UP. Effects of alpha-crystalline on lens cell function and cataract pathology. Curr Mol Med 2009;9:887–892
  • Ohira A, Ueda T, Ohishi K, Hiramitsu T, Akeo K, Obara Y. [Oxidative stress in ocular disease]. Nihon Ganka Gakkai Zasshi 2008;112:22–29

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