Association of Platelet Glycoprotein Receptor Alpha2beta1 Integrin and Glycoprotein IIIa Gene Polymorphisms with Diabetic Retinopathy: Evidence from 3007 Subjects

References

• Shah CA. Diabetic retinopathy: a comprehensive review. Indian J Med Sci 2008;62:500–519
   PubMedGoogle Scholar
• Resnikoff S, Pascolini D, Etya’ale D, Kocur I, Pararajasegaram R, Pokharel GP, et al. Global data on visual impairment in the year 2002. Bull World Health Organ 2004;82:844–851
   PubMed Web of Science ®Google Scholar
• Porta M, Sjoelie AK, Chaturvedi N, Stevens L, Rottiers R, Veglio M, et al. Risk factors for progression to proliferative diabetic retinopathy in the EURODIAB Prospective Complications Study. Diabetologia 2001;44:2203–2209
   PubMed Web of Science ®Google Scholar
• Patel S, Chen H, Tinkham NH, Zhang K. Genetic susceptibility of diabetic retinopathy. Curr Diab Rep 2008;8:257–262
   PubMedGoogle Scholar
• Balasubbu S, Sundaresan P, Rajendran A, Ramasamy K, Govindarajan G, Perumalsamy N, et al. Association analysis of nine candidate gene polymorphisms in Indian patients with type 2 diabetic retinopathy. BMC Med Genet 2010;11:158
   PubMed Web of Science ®Google Scholar
• Stratmann B, Tschoepe D. Pathobiology and cell interactions of platelets in diabetes. Diab Vasc Dis Res 2005;2:16–23
   PubMedGoogle Scholar
• Sixma JJ, van Zanten GH, Huizinga EG, van der Plas RM, Verkley M, Wu YP, et al. Platelet adhesion to collagen: an update. Thromb Haemost 1997;78:434–438
   PubMed Web of Science ®Google Scholar
• Kritzik M, Savage B, Nugent DJ, Santoso S, Ruggeri ZM, Kunicki TJ. Nucleotide polymorphisms in the alpha2 gene define multiple alleles that are associated with differences in platelet alpha2 beta1 density. Blood 1998;92:2382–2388
   PubMed Web of Science ®Google Scholar
• Lefkovits J, Plow EF, Topol EJ. Platelet glycoprotein IIb/IIIa receptors in cardiovascular medicine. N Engl J Med 1995;332:1553–1559
   PubMed Web of Science ®Google Scholar
• Papp E, Havasi V, Bene J, Komlosi K, Czopf L, Magyar E, et al. Glycoprotein IIIA gene (PlA) polymorphism and aspirin resistance: is there any correlation? Ann Pharmacother 2005;39:1013–1018
   Google Scholar
• Azmy R, Dawood A, Kilany A, El-Ghobashy Y, Ellakwa AF, El-Daly M. Association analysis of genetic variations of eNOS and α2β1 integrin genes with type 2 diabetic retinopathy. Appl Clin Genet 2012;5:55–65
   PubMedGoogle Scholar
• Li H, Louey JW, Choy KW, Liu DT, Chan WM, Chan YM, et al. EDN1 Lys198Asn is associated with diabetic retinopathy in type 2 diabetes. Mol Vis 2008;14:1698–1704
   PubMedGoogle Scholar
• Zhang JX, Yi H. Association of platelet GPIa gene polymorphism with diabetic retinopathy. J Pract Med 2005;21:1899–1901
   Google Scholar
• Petrovic MG, Hawlina M, Peterlin B, Petrovic D. BglII gene polymorphism of the alpha2beta1 integrin gene is a risk factor for diabetic retinopathy in Caucasians with type 2 diabetes. J Hum Genet 2003;48:457–460
   Google Scholar
• Pavkovic M, Dimitrovski C, Laban GN, Percan V, Arsov T, Jankova R, et al. The polymorphisms of platelet glycoprotein receptors IIIa and Ia and their relationship with diabetic retinopathy in patients with type 2 diabetes mellitus. Blood 2001;98:97b
   Google Scholar
• Matsubara Y, Murata M, Maruyama T, Handa M, Yamagata N, Watanabe G, et al. Association between diabetic retinopathy and genetic variations in alpha2beta1 integrin, a platelet receptor for collagen. Blood 2000;95:1560–1564
   PubMed Web of Science ®Google Scholar
• Arsène S, Pouplard C, Perrodeau E, Delbachian I, Giraudeau B, Maillot F, et al. No association between the ITGA2 807T allele and retinopathy in french patients with type 2 diabetes. Thromb Res 2011;128:293–295
   Google Scholar
• Reiner AP, Agardh E, Teramura G, Gaur P, Gaur LK, Agardh CD. Diabetes duration may modify the association between genetic variation in the glycoprotein Ia subunit of the platelet collagen receptor and risk of severe diabetic retinopathy: a working hypothesis. Thromb Haemost 2003;89:142–148
   Google Scholar
• Nikolajević-Starčević J, Petrovič MG, Petrovič D. A1/A2 polymorphism of the glycoprotein IIIa gene and diabetic retinopathy in Caucasians with type 2 diabetes. Clin Experiment Ophthalmol 2011;39:665–672
   Google Scholar
• Pucci L, Lucchesi D, Fotino C, Grupillo M, Miccoli R, Penno G, et al. Integrin Beta 3 PlA1/PlA2 polimorphism does not contribute to complications in both type 1 and type 2 diabetes. G Ital Nefrol 2003;20:461–469
   Google Scholar
• Munafo MR, Flint J. Meta-analysis of genetic association studies. Trends Genet 2004;20:439–444
   PubMed Web of Science ®Google Scholar
• Wells GA, Shea B, O’Connell D, Peterson J, Welch V, Losos M, et al. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. Available from: http://www.ohri.ca/programs/clinical_epidemiology/oxford.asp. 2013
   Google Scholar
• Cochran WG. The combination of estimates from different experiments. Biometrics 1954;10:101–129
   Web of Science ®Google Scholar
• Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med 2002;21:1539–1558
   PubMed Web of Science ®Google Scholar
• Mantel N, Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 1959;22:719–748
   PubMed Web of Science ®Google Scholar
• DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986;7:177–188
   PubMed Web of Science ®Google Scholar
• Egger M, Davey SG, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. Br Med J 1997;315:629–634
   PubMed Web of Science ®Google Scholar
• Zhang JX, Xu MC, Zhu YL, Ye LX, Fan YJ, Sun SX, et al. The relationship between platelet integrin α2β1 gene polymorphism and diabetic retinopathy. Zhonghua Nei Ke Za Zhi 2003;42:119–120
   Google Scholar
• Zhang JX, Xu MC, Zhu YL, Fan YJ, Sun SX, Deng HH. Study on the relationship between the platelet α2β1 integrin gene polymorphism and diabetic microangiopathy. J Clin Intern Med 2003;20:203–205
   Google Scholar
• Kunicki TJ, Kritzik M, Annis DS, Nugent DJ. Hereditary variation in platelet integrin alpha 2 beta 1 density is associated with two silent polymorphisms in the alpha 2 gene coding sequence. Blood 1997;89:1939–1943
   PubMed Web of Science ®Google Scholar
• Pavkovic M, Petlichkovski A, Stojanovic A, Trajkov D, Spiroski M. BgI II polymorphism of the α2β1 integrin gene in Macedonian population. Maced J Med Sci 2010;3:119–122
   Google Scholar
• Michelson AD, Furman MI, Goldschmidt-Clermont P, Mascelli MA, Hendrix C, Coleman L, et al. Platelet GP IIIa Pl(A) polymorphisms display different sensitivities to agonists. Circulation 2000;101:1013–1018
   PubMed Web of Science ®Google Scholar
• Undas A, Brummel K, Musial J, Mann KG, Szczeklik A. Pl(A2) polymorphism of beta(3) integrins is associated with enhanced thrombin generation and impaired antithrombotic action of aspirin at the site of microvascular injury. Circulation 2001;104:2666–2672
   PubMed Web of Science ®Google Scholar