625
Views
11
CrossRef citations to date
0
Altmetric
Original Article

Stability of Latanoprost in Generic Formulations Using Controlled Degradation and Patient Usage Simulation Studies

, , , , &
Pages 561-571 | Received 30 Jan 2014, Accepted 22 Jun 2014, Published online: 11 Dec 2014

References

  • George R, Ve RS, Vijaya L. Glaucoma in India: estimated burden of disease. J Glaucoma 2010;19:391–397
  • Quigley HA, Broman AT. The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol 2006;90:262–267
  • Weinreb RN, Toris CB, Gabelt BT, Lindsey JD, Kaufman PL. Effects of prostaglandins on the aqueous humor outflow pathways. Surv Ophthalmol 2002;47:53–64
  • Heijl A, Leske MC, Bengtsson B, Hyman L, Bengtsson B, Hussein M. Reduction of intraocular pressure and glaucoma progression: results from the Early Manifest Glaucoma Trial. Arch Ophthalmol 2002;120:1268–1279
  • Kass MA, Heuer DK, Higginbotham EJ, Johnson CA, Keltner JL, Miller JP, et al. The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma. Arch Opthalmol 2002;120:701–713
  • Maier PC, Funk J, Schwarzer G, Antes G, Falck-Ytter YT. Treatment of ocularhypertension and open angle glaucoma: meta-analysis of randomised controlled trials. BMJ 2005;331:134
  • Husain S, Yates PW, Crosson CE. Latanoprost-induced changes in rat intraocular pressure: direct or indirect. J Ocul Pharmacol Ther 2008;24:367–372
  • Collaborative Normal- Tension Glaucoma Study Group. The effectiveness of intraocular pressure reduction in the treatment of normal-tension glaucoma. Am J Ophthalmol 1998;126:498–505
  • Resul B, Stjernschantz J. Overview: Structure-activity relationships of prostaglandin analogues as ocular hypotensive agents. Expert Opin Ther Pat 1993;3:781–795
  • Stjernschantz JW. From PGF2a-isopropyl ester to latanoprost: a review of the development of xalatan. IOVS 2001;42:61134–61145
  • Morgan PV, Proniuk S, Blanchard J, Noecker RJ. Effect of temperature and light on the stability of latanoprost and its clinical relevance. J Glaucoma 2001;10:401–405
  • Sakai Y, Yasueda S, Ohtori A. Stability of latanoprost in an ophthalmic lipid emulsion using polyvinyl alcohol. Int J Pharm 2005;23:176–179
  • Ochiai A, Danjo K. The stabilization mechanism of latanoprost. Int J Pharm 2011;30:23–30
  • Kahook MY, Fechtner RD, Katz LJ, Noecker RJ, Ammar DA. A comparison of active ingredients and preservatives between brand name and generic topical glaucoma medications using liquid chromatography-tandem mass spectrometry. Curr Eye Res 2012;37:101–108
  • Johnson TV, Gupta PK, Vudathala DK, Blair IA, Tanna AP. Thermal stability of bimatoprost, latanoprost, and travoprost under simulated daily use. J Ocul Pharmacol Ther 2011;27:51–59
  • Mochizuki H, Itakura H, Takamatsu M, Kiuchi Y. Efficacy of latanoprost when stored at room temperature. Hiroshima J Med Sci 2008;57:69–72
  • Singh R, Rehman Z.U. Current trends in forced degradation study for pharmaceutical product development. J Pharm Educ Res 2012;3:54–63
  • Mehta J, Patel V, Kshatri N, Vyas N. A versatile LC method for the simultaneous quantification of latanoprost, timolol and benzalkonium chloride and related substances in the presence of their degradation products in ophthalmic solution. Anal Methods 2010;2:1737–1744
  • Collins PW, Pappo R, Dajani EZ. Chemistry and synthetic development of misoprostol. Dig Dis Sci 1985;30:114s–117s
  • Vemuri N. Preformulation. In: Nema S, Ludwig JD, editors. Pharmaceutical dosage forms in parenteral medications, 3rd ed. New York: Informa Healthcare; 2010. pp. 57--75
  • Boquet MP, Wagner DR. Injectable formulations of poorly water soluble drugs. In: Williams RO, Watts AB, Miller DA, editors. Formulating poorly water soluble drugs. AAPS Press Springer; 2012. pp 209–242
  • Salomon RG, Lipid research laboratory, Mechanisms of lipid oxidative fragmentation. Available from: www.case.edu/artsci/chem/faculty/salomon/Mechanisms.htm [last accessed 13 Jan 2014]
  • Varma R, Winarko J, Kiat-Winarko T, Winarko B. Concentration of latanoprost ophthalmic solution after 4 to 6 weeks’ use in an eye clinic setting. Invest Ophthalmol Vis Sci 2006;47:222–225
  • Paolera MD, Kasahara N, Umbelino CC, Walt JG. Comparative study of the stability of bimatoprost 0.03% and latanoprost 0.005%: a patient-use study. BMC Ophthalmol 2008;8(11):1--5

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.