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Original Article

Lactoferrin Reduces Chorioretinal Damage in the Murine Laser Model of Choroidal Neovascularization

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Pages 946-953 | Received 28 Jan 2014, Accepted 18 Sep 2014, Published online: 02 Apr 2015

References

  • Folkman J, Shing Y. Angiogenesis. J Biol Chem 1992;267:10931–10934
  • Sheybani A, Almony A, Blinder KJ, Shah GK. Neovascular age-related macular degeneration and anti-VEGF nonresponders. Expert Rev Ophthalmol 2010;5:35–41
  • Hayreh SS, Rojas P, Podhajsky P, Montague P, Woolson RF. Ocular Neovascularization with Retinal Vascular Occlusion-III: incidence of ocular neovascularization with retinal vein occlusion. Ophthalmology 1983;90:488–506
  • Alon T, Hemo I, Itin A, Pe'er J, Stone J, Keshet E. Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity. Nat Med 1995;10:1024–1028
  • Suzuki M, Nagai N, Izumi-Nagai K, Shinoda H, Koto T, Ushida A, et al. Predictive factors for non-response to intravitreal ranibizumab treatment in age-related macular degeneration. Br J Ophthalmol 2014;98:1186–1191
  • Baker EN, Baker HM. Molecular structure, binding properties and dynamics of lactoferrin. Cell Mol Life Sci 2005;62:2531–2539
  • Baggiolini M, De Duve C, Masson PL, Heremans JF. Association of lactoferrin with specific granules in rabbit heterophil leukocytes. J Exp Med 1970;131:559–570
  • Flanagan JL, Willcox MD. Role of lactoferrin in the tear film. Biochimie 2009;91:35–43
  • Clausen R, Weller M, Wiedemann P, Heimann K, Hilgers RD, Zilles K. An immunochemical quantitative analysis of the protein pattern in physiologic and pathologic vitreous. Graefes Arch Clin Exp Ophthalmol 1991;229:186–190
  • Metz-Boutique MH, Jolles J, Mazurier J, Schoentgen F, Legrand D, Spik G, et al. Human lactotransferrin: amino acid sequence and structural comparisons with other transferrins. Eur J Biochem 1984;145:659–676
  • Arnold RR, Brewer M, Gauthier JJ. Bactericidal activity of human lactoferrin: sensitivity of a variety of microorganisms. Infect Immun 1980;28:893–898
  • Mariller C, Hardiville S, Hoedt E, Huvent I, Pina-Canseco S, Pierce A. Delta-lactoferrin, an intracellular lactoferrin isoform that acts as a transcription factor. Biochem Cell Biol 2012;90:307–319
  • Pandey V, Gaibhiye KR, Soni V. Lactoferrin-appended solid lipid nanoparticles of paclitaxel for effective management of bronchogenic carcinoma. Drug Deliv 2015;22:199–205
  • Norrby K, Mattsby-Baltzer I, Innocenti M, Tuneberg S. Orally administered bovine lactoferrin systemically inhibits VEGF (165)-mediated angiogenesis in the rat. Int J Cancer 2001;91:236–240
  • Mader JS, Smyth D, Marshall J, Hoskin DW. Bovine lactoferricin inhibits basic fibroblast growth factor- and vascular endothelial growth factor165-induced angiogenesis by competing for heparin-like binding sites on endothelial cells. Am J Pathol 2006;169:1753–1766
  • Yeom M, Park J, Lee B, Choi S, Soo Kim K, Lee J, et al. Lactoferrin inhibits the inflammatory and angiogenic activation of bovine aortic endothelial cells. Inflamm Res 2011;60:475–482
  • Jung YJ, Isaacs JS, Lee S, Trepel J, Neckers L. IL-1beta-mediated up-regulation of HIF-1alpha via an NFkappaB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis. FASEB J 2003;17:2115–2117
  • Haversen L, Ohlsson BG, Hahn-Zoric M, Hanson LA, Mattsby-Balzer I. Lactoferrin down-regulates the LPS-induced cytokine production in monocytic cells via NF-kappa B. Cell Immunol 2002;220:83–95
  • Shimamura M, Yamamoto Y, Ashino H, Oikawa T, Hazato T, Tsuda H, et al. Bovine lactoferrin inhibits tumor-induced angiogenesis. Int J Cancer 2004;111:111–116
  • Ward P, Mendoza-Meneses M, Cunningham G, Conneely O. Iron status in mice carrying a targeted disruption of lactoferrin. Mol Cell Biol 2003;23:178–185
  • Montezuma SR, Vavvas D, Miller JW. Review of the ocular angiogenesis animal models. Semin Ophthalmol 2009;24:52–61
  • Marneros AG, She H, Zambarakji H. Endogenous endostatin inhibits choroidal neovascularization. FASEB J 2007;21:3809–3818
  • Krzystolik MG, Afshari MA, Adamis AP, Gaudreault J, Gragoudas ES, Michaud NA, et al. Prevention of experimental choroidal neovascularization with intravitreal antivascular endothelial growth factor antibody fragment. Arch Ophthalmol 2002;120:338–346
  • Yamada K, Sakurai E, Itaya M, Yamasaki S, Ogura Y. Inhibition of laser-induced choroidal neovascularization by atorvastatin by downregulation of monocyte chemotactic protein-1 synthesis in mice. Invest Ophthalmol Vis Sci 2007;48:1839–1843
  • Tamai K, Spaide RF, Ellis EA, Ogura Y, Armstrong D. Lipid hydroperoxide stimulates subretinal choroidal neovascularization in the rabbit. Exp Eye Res 2002;74:301–308
  • Ueda T, Ueda T, Fukuda S, Browne R, Jenis E, Spengler R, et al. Lipid hydroperoxide-induced tumor necrosis factor (TNF)-alpha, vascular endothelial growth factor and neovascularization in the rabbit cornea: effect of TNF inhibition. Angiogenesis 1998;1:174–184
  • Armstrong D, Ueda T, Ueda T, Aljada A, Browne R, Fukuda S, et al. Lipid hydroperoxide stimulates retinal neovascularization in rabbit retina through expression of tumor necrosis factor-alpha, vascular endothelial growth factor and platelet-derived growth factor. Angiogenesis 1998;2:93–104
  • Kress GJ, Dineley KE, Reynolds IJ. The relationship between intracellular free iron and cell injury in cultured neurons, astrocytes, and oligodendrocytes. J Neurosci 2002;22:5848–5855

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