Advanced search
Publication Cover
Current Eye Research Volume 41, 2016 - Issue 12
Submit an article Journal homepage
252
Views
8
CrossRef citations to date
0
Altmetric
Retina and Uvea

A Novel Tool for the Assessment Oxidative Stress in Age-Related Macular Degeneration: Thiol/Disulfide Homeostasis Revisited

Mücella Arıkan YorgunDepartment of Ophthalmology, Ankara Atatürk Education and Research Hospital, Yıldırım Beyazıt University, Ankara, TurkeyCorrespondence[email protected]
,
Yasin TokluDepartment of Ophthalmology, Ankara Atatürk Education and Research Hospital, Yıldırım Beyazıt University, Ankara, Turkey
,
Hasan AltınkaynakDepartment of Ophthalmology, Ankara Atatürk Education and Research Hospital, Yıldırım Beyazıt University, Ankara, Turkey
,
Burak TanrıverdiDepartment of Ophthalmology, Ankara Atatürk Education and Research Hospital, Yıldırım Beyazıt University, Ankara, Turkey
,
Merve ErginDepartment of Biochemistry, Ankara Atatürk Education and Research Hospital, Yıldırım Beyazıt University, Ankara, Turkey
&
Cemile BiçerDepartment of Biochemistry, Ankara Atatürk Education and Research Hospital, Yıldırım Beyazıt University, Ankara, Turkey
Pages 1584-1589 | Received 16 Sep 2015, Accepted 05 Jan 2016, Published online: 03 Jun 2016

References

  • Klein R, Peto T, Bird A, Vannewkirk MR. The epidemiology of age-related macular degeneration. Am J Ophthalmol 2004;137:486–495.
  • Blasiak J, Petrovski G, Vereb Z, Facsko A, Kaarniranta K. Oxidative stress, hypoxia, and autophagy in the neovascular processes of age-related macular degeneration. BioMed Res Int 2014;2014:768026.
  • Kaarniranta K, Salminen A, Eskelinen EL, Kopitz J. Heat shock proteins as gatekeepers of proteolytic pathways-Implications for age-related macular degeneration (AMD). Ageing Res Rev 2009;8:128–139.
  • Samiec PS, Drews-Botsch C, Flagg EW, Kurtz JC, Sternberg P, Jr., Reed RL, et al. Glutathione in human plasma: decline in association with aging, age-related macular degeneration, and diabetes. Free Radic Biol Med 1998;24:699–704.
  • Beatty S, Koh H, Phil M, Henson D, Boulton M. The role of oxidative stress in the pathogenesis of age-related macular degeneration. Surv Ophthalmol 2000;45:115–134.
  • Tate DJ, Jr., Miceli MV, Newsome DA. Phagocytosis and H2O2 induce catalase and metallothionein gene expression in human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 1995;36:1271–1279.
  • Kennedy CJ, Rakoczy PE, Constable IJ. Lipofuscin of the retinal pigment epithelium: a review. Eye 1995;9:763–771.
  • Curcio CA, Owsley C, Jackson GR. Spare the rods, save the cones in aging and age-related maculopathy. Invest Ophthalmol Vis Sci 2000;41:2015–2018.
  • Atmaca G. Antioxidant effects of sulfur-containing amino acids. Yonsei med J 2004;45:776–788.
  • Jones DP, Liang Y. Measuring the poise of thiol/disulfide couples in vivo. Free radic Biol Med 2009;47:1329–1338.
  • Go YM, Jones DP. Cysteine/cystine redox signaling in cardiovascular disease. Free radic Biol Med 2011;5:495–509.
  • Prabhu A, Sarcar B, Kahali S, Yuan Z, Johnson JJ, Adam KP, et al. Cysteine catabolism: a novel metabolic pathway contributing to glioblastoma growth. Cancer Res 2014;74:787–796.
  • Tetik S, Ahmad S, Alturfan AA, Fresko I, Disbudak M, Sahin Y, et al. Determination of oxidant stress in plasma of rheumatoid arthritis and primary osteoarthritis patients. Indian J Biochem Biophy 2010;47:353–358.
  • Kundi H, Erel O, Balun A, Cicekcioglu H, Cetin M, Kiziltunc E, et al. Association of thiol/disulfide ratio with syntax score in patients with NSTEMI. Scan Cardiovasc J 2015;49(2):95–100.
  • Erel O, Neselioglu S. A novel and automated assay for thiol/disulphide homeostasis. Clin Biochem 2014;47(18):326–332.
  • Age-Related Eye Disease Study Research Group. The Age-Related Eye Disease Study system for classifying age-related macular degeneration from stereoscopic color fundus photographs: the Age-Related Eye Disease Study Report Number 6. Am J Ophthalmol 2001;132:668–681.
  • Winkler BS, Boulton ME, Gottsch JD, Sternberg P. Oxidative damage and age-related macular degeneration. Mol Vis 1999;5:32.
  • Jiang S, Moriarty-Craige SE, Orr M, Cai J, Sternberg P, Jr., Jones DP. Oxidant-induced apoptosis in human retinal pigment epithelial cells: dependence on extracellular redox state. Invest Ophthalmol Vis Sci 2005;46:1054–1061.
  • Delcourt C, Cristol JP, Tessier F, Leger CL, Descomps B, Papoz L. Age-related macular degeneration and antioxidant status in the POLA study. POLA Study Group. Arch Ophthalmol 1999;117:1384–1390.
  • Cadenas E. Biochemistry of oxygen toxicity. Annu rev Biochem 1989;58:79–110.
  • Hu ML. Measurement of protein thiol groups and glutathione in plasma. Methods Enzymol 1994;233:380–385.
  • Di Mascio P, Murphy ME, Sies H. Antioxidant defense systems: the role of carotenoids, tocopherols, and thiols. Am J Clin Nutr 1991;53(1 Suppl):194S–200S.
  • Coral K, Raman R, Rathi S, Rajesh M, Sulochana KN, Angayarkanni N, et al. Plasma homocysteine and total thiol content in patients with exudative age-related macular degeneration. Eye 2006;20:203–207.
  • Ugurlu N, Asik MD, Yulek F, Neselioglu S, Cagil N. Oxidative stress and anti-oxidative defence in patients with age-related macular degeneration. Curr Eye Res 2013;38:497–502.
  • Dong A, Xie B, Shen J, Yoshida T, Yokoi K, Hackett SF, et al. Oxidative stress promotes ocular neovascularization. J Cell Physiol 2009;219:544–552.
  • Evereklioglu C, Er H, Doganay S, Cekmen M, Turkoz Y, Otlu B, et al. Nitric oxide and lipid peroxidation are increased and associated with decreased antioxidant enzyme activities in patients with age-related macular degeneration. Doc Ophthalmol 2003;106:129–136.
  • Ehrlich R, Harris A, Kheradiya NS, Winston DM, Ciulla TA, Wirostko B. Age-related macular degeneration and the aging eye. Clin Interv Aging 2008;3:473–482.
  • Khandhadia S, Lotery A. Oxidation and age-related macular degeneration: insights from molecular biology. Expert Rev Mol Med 2010;12:e34.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.