Role of Autophagy in Hypoxia-Induced Angiogenesis of RF/6A Cells in vitro

References

• de Jong PT. Age-related macular degeneration. N Engl J Med 2006;355:1474–1485.
   PubMed Web of Science ®Google Scholar
• Mintz-Hittner HA, Kennedy KA, Chuang AZ, BEAT-ROP Cooperative Group. Efficacy of intravitreal bevacizumab for stage 3+ retinopathy of prematurity. N Engl J Med 2011;364:603–615.
   PubMed Web of Science ®Google Scholar
• Aiello LM. Perspectives on diabetic retinopathy. Am J Ophthalmol 2003;136:122–135.
   PubMed Web of Science ®Google Scholar
• Li SY, Fu ZJ, Lo AC. Hypoxia-induced oxidative stress in ischemic retinopathy. Oxid Med Cell Longev 2012;2012:426769.
   PubMed Web of Science ®Google Scholar
• Aragones J, Fraisl P, Baes M, Carmeliet P. Oxygen sensors at the crossroad of metabolism. Cell Metab 2009;9:11–22.
   PubMed Web of Science ®Google Scholar
• Maxwell PH, Ratcliffe PJ. Oxygen sensors and angiogenesis. Semin Cell Dev Biol 2002;13:29–37.
   PubMed Web of Science ®Google Scholar
• Abounit K, Scarabelli TM, McCauley RB. Autophagy in mammalian cells. World J Biol Chem 2012;3:1–6.
   PubMedGoogle Scholar
• Ramakrishnan S, Nguyen TM, Subramanian IV, Kelekar A. Autophagy and angiogenesis inhibition. Autophagy 2007;3:512–515.
   PubMed Web of Science ®Google Scholar
• Du J, Teng RJ, Guan T, Eis A, Kaul S, Konduri GG, et al. Role of autophagy in angiogenesis in aortic endothelial cells. Am J Physiol Cell Physiol 2012;302:C383–C391.
   PubMed Web of Science ®Google Scholar
• Clark SL Jr. Cellular differentiation in the kidneys of newborn mice studies with the electron microscope. J Biophys Biochem Cytol 1957;3:349–362.
   PubMedGoogle Scholar
• Ashford TP, Porter KR. Cytoplasmic components in hepatic cell lysosomes. J Cell Biol 1962;12:198–202.
   PubMed Web of Science ®Google Scholar
• Orvedahl A, Sumpter R Jr., Xiao G, Ng A, Zou Z, Tang Y, et al. Image-based genome-wide siRNA screen identifies selective autophagy factors. Nature 2011;480:113–117.
   PubMed Web of Science ®Google Scholar
• Zhao Y, Xiong X, Sun Y. DEPTOR, an mTOR inhibitor, is a physiological substrate of SCF (betaTrCP) E3 ubiquitin ligase and regulates survival and autophagy. Mol Cell 2011;44:304–316.
   PubMed Web of Science ®Google Scholar
• Singh R, Kaushik S, Wang Y, Xiang Y, Novak I, Komatsu M, et al. Autophagy regulates lipid metabolism. Nature 2009;458:1131–1135.
   PubMed Web of Science ®Google Scholar
• Rabinowitz JD, White E. Autophagy and metabolism. Science 2010;330:1344–1348.
   PubMed Web of Science ®Google Scholar
• Tsuchihara K, Fujii S, Esumi H. Autophagy and cancer: dynamism of the metabolism of tumor cells and tissues. Cancer Lett 2009;278:130–138.
   PubMed Web of Science ®Google Scholar
• Mihaylova MM, Shaw RJ. The AMPK signalling pathway coordinates cell growth, autophagy and metabolism. Nat Cell Biol 2011;13:1016–1023.
   PubMed Web of Science ®Google Scholar
• Maiuri MC, Le Toumelin G, Criollo A, Rain JC, Gautier F, Juin P, et al. Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1. EMBO J 2007;26:2527–2539.
   PubMed Web of Science ®Google Scholar
• Mizushima N, Yoshimori T, Levine B. Methods in mammalian autophagy research. Cell 2010;140:313–326.
   PubMed Web of Science ®Google Scholar
• Ueno T, Sato W, Horie Y, Komatsu M, Tanida I, Yoshida M, et al. Loss of Pten, a tumor suppressor, causes the strong inhibition of autophagy without affecting LC3 lipidation. Autophagy 2008;4:692–700.
   PubMed Web of Science ®Google Scholar
• Wu YT, Tan HL, Shui G, Bauvy C, Huang Q, Wenk MR, et al. Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase. J Biol Chem 2010;285:10850–10861.
   PubMed Web of Science ®Google Scholar
• Mazure NM, Pouyssegur J. Hypoxia-induced autophagy: cell death or cell survival? Curr Opin Cell Bio 2010;22:177–180.
   PubMed Web of Science ®Google Scholar
• Rosen R, Vagaggini T, Chen Y, Hu DN. Zeaxanthin inhibits hypoxia-induced VEGF secretion by RPE cells through decreased protein levels of hypoxia-inducible factors-1α. Biomed Res Int 2015;2015:687386.
   PubMed Web of Science ®Google Scholar
• Wu BX, Darden AG, Laser M, Li Y, Crosson CE, Hazard ES 3rd, et al. The rat Apg3p/Aut1p homolog is upregulated by ischemic preconditioning in the retina. Mol Vis 2006;12:1292–1302.
   Google Scholar
• Kunchithapautham K, Rohrer B. Apoptosis and autophagy in photoreceptors exposed to oxidative stress. Autophagy 2007;3:433–441.
   PubMed Web of Science ®Google Scholar
• Ramakrishnan S, Nguyen TM, Subramanian IV, Kelekar A. Autophagy and angiogenesis inhibition. Autophagy 2007;3:512–515.
   PubMed Web of Science ®Google Scholar
• Mitter SK, Rao HV, Qi X, Cai J, Sugrue A, Dunn WA Jr, et al. Autophagy in the retina: a potential role in age-related macular degeneration. Adv Exp Med Biol 2012;723:83–90.
   PubMed Web of Science ®Google Scholar
• Zhao W, Wang YS, Hui YN, Zhu J, Zhang P, Li X, et al. Inhibition of proliferation, migration and tube formation of choroidal microvascular endothelial cells by targeting HIF-1alpha with short hairpin RNA-expressing plasmid DNA in human RPE cells in a coculture system. Graefes Arch Clin Exp Ophthalmol 2008;246:1413–1422.
   PubMed Web of Science ®Google Scholar
• Sheridan CM, Pate S, Hiscott P, Wong D, Pattwell DM, Kent D. Expression of hypoxia-inducible factor-1alpha and -2alpha in human choroidal neovascular membranes. Graefes Arch Clin Exp Ophthalmol 2009;247:1361–1367.
   PubMed Web of Science ®Google Scholar
• André H, Tunik S, Aronsson M, Kvanta A. Hypoxia-inducible factor-1α is associated with sprouting angiogenesis in the murine laser-induced choroidal neovascularization model. Invest Ophthalmol Vis Sci 2015;56:6591–6604.
   PubMed Web of Science ®Google Scholar
• Balaiya S, Murthy RK, Chalam KV. Resveratrol inhibits proliferation of hypoxic choroidal vascular endothelial cells. Mol Vis 2013;19:2385–2392.
   PubMed Web of Science ®Google Scholar
• Zamora DO, Riviere M, Choi D, Pan Y, Planck SR, Rosenbaum JT, et al. Proteomic profiling of human retinal and choroidal endothelial cells reveals molecular heterogeneity related to tissue of origin. Mol Vis 2007;13:2058–2065.
   PubMed Web of Science ®Google Scholar
• Stewart EA, Samaranayake GJ, Browning AC, Hopkinson A, Amoaku WM. Comparison of choroidal and retinal endothelial cells: characteristics and response to VEGF isoforms and anti-VEGF treatments. Exp Eye Res 2011;93:761–766.
   PubMed Web of Science ®Google Scholar