9
Views
10
CrossRef citations to date
0
Altmetric
Original Article

Conformational changes in soluble lens proteins during the development of senile nuclear cataract

&
Pages 571-583 | Received 18 Jul 1983, Accepted 17 Jan 1984, Published online: 02 Jul 2009

References

  • Pirie A. Colour and solubility of the proteins of human cataract. Invest. Opthalmol. 1968; 7: 634–650
  • Truscott R. J., Augusteyn R. C. Changes in human lens proteins during senile nuclear cataract formation. Exp. Eye Res. 1977; 24: 159–170
  • Dische Z., Zil H. Studies on the oxidation of cysteine to cystine in lens proteins during cataract formation. Amer. J. Ophthalmol. 1951; 34: 104–113
  • Augusteyn R. C. Distribution of fluorescence in the human cataractous lens. Opthal. Res. 1975; 7: 217–224
  • Truscott R. J., Augusteyn R. C. Oxidative changes in human lens proteins during senile nuclear cataract formation. Biochim. Biophys. Acta 1977; 492: 43–52
  • Truscott R. J., Augusleyn R. C. The state of sulphydryl groups in normal and cataractous human lenses. Exp. Eye Res. 1977; 25: 139–148
  • van Haard P. M.M., Kramps J. A., Hoenders H. J., Wollensak J. Development of non‐disulphide covalent cross‐links in nuclear cataractogenesis. Interdiscipl. Topics Gerontol. 1978; 13: 212–224
  • Augusteyn R. C. Mechanisms of Cataract Formation in the Human Lens, G. Duncan, 1981; 71–115
  • Harding J. J. Molecular and Cellular Biology of the Eye Lens, H. Bloemendal. J. Wiley and Sons, New York 1981; 327–365
  • Harding J. J. Conformational changes in human lens proteins in cataract. Biochem. J. 1972; 129: 97–100
  • Kurzel R. B., Wolbarscht M., Yamanishi B. S., Staton G. W., Borkman R. F. Tryptophan excited states and cataracts in the human lens. Nature 1973; 241: 132–133
  • Laemmli V. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227: 680–685
  • Lowry O. H., Rosenberg N. J., Farr A. L., Randall R. J. Protein measurement with the Folin‐Phenol reagents. J. Biol. Chem. 1951; 193: 265–275
  • Bjork I. Studies on γ crystallin from calf lens I. Isolation by gel filtration. Exp. Eye Res. 1961; 1: 145–154
  • Reif A. E. Batch preparation of rabbit G globulin with DEAE‐cellulose. Immunochem 1969; 6: 723–731
  • Bolton A. E. Radioiodination techniques Review 18. The Radiochemical Centre, AmershamEngland 1977
  • Kramps H. A., Hoenders H. J., Wollensak J. Protein changes in the human lens during development of senile nuclear cataracts. Biochim. Biophys Acta 1976; 434: 32–43
  • Zigler J. S., Horwitz J., Kinoshita J. Studies on the low molecular weight proteins of human lens. Exp. Eye Res. 1981; 32: 21–30
  • Clark R., Zigman S., Lerman S. Studies on the structural proteins of the human lens. Exp. Eye Res. 1969; 8: 172–182
  • Coghlan S., Augusteyn R. C. Changes in the distribution of proteins in the aging human lens. Exp. Eye Res. 1977; 25: 603–611
  • Jedziniak J. A., Baram H., Chylak L. T. The molecular distribution, weight determination and concentration variation of total water soluble proteins of the human lens. Exp. Eye Res. 1978; 26: 377–388
  • Manski W., Malinowski K., Bonitsis G. Immunochemical studies on lens protein‐protein complexes. I. The heterogeneity and structure of complexed alpha crystallin. Exp. Eye Res. 1980; 29: 625–636
  • Garner W. H., Garner M. H., Spector A. Gamma‐crystallin, a major cytoplasmic polypeptide disulphide linked to membrane proteins in human cataract. Biochem. Biophys. Res. Commun. 1981; 98: 437–447
  • Burstein E. A., Vedenkina N. S., Ivkova M. N. Fluorescence and the location of tryptophan residues in protein molecules. Photochem. Photobiol. 1973; 18: 263–279
  • Borkman R., Lerman S. Fluorescence spectra of tryptophan residues in human and bovine lens proteins. Exp. Eye Res. 1978; 26: 705–713
  • Sandberg H. O. The alhpa‐crystallin content of aqueous humor in cortical nuclear and complicated cataracts. Exp. Eye Res. 1976; 22: 75–84
  • Sandberg H. O., Closs O. Radioimmunoassay of sheep alpha‐ and gamma‐crystallins I. 125I Labelling of sheep gammacrystallin. Characterization of assays in detecting homologous and heterologous lens crystallins. Exp. Eye Res. 1978; 27: 61–71
  • Zigler J. S., Carper J., Russell P., Kinoshita J. Analysis of some immunochemical properties of human β crystal lin by radioimmunoassay. Exp. Eye Res. 1980; 31: 389–397
  • Sandberg H. O., Closs O. The alpha and gamma crystallin content in aqueous humor of eyes with clear lenses and with cataracts. Exp. Eye Res. 1978; 28: 601–610
  • Russell P., Carper D., Kinoshita J. H. The development and application of a radioimmunoassay to lens crystallins. Exp. Eye Res. 1978; 27: 673–681
  • Sandberg H. O., Closs O. Specific Radioimmunoassays for Human Alpha and Gamma Crystallins. Exp. Eye Res. 1978; 27: 701–712
  • Kabasawa I., Sakaue E., Fukui H. N. Fetal calf lens γ crystallins. Jap. J. Ophthalmol. 1978; 22: 74–80

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.