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Original Article

Alpha-2 adrenergic modulation of norepinephrine secretion in the perfused rabbit iris-ciliary body

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Pages 767-777 | Received 02 Jan 1987, Accepted 13 Apr 1987, Published online: 02 Jul 2009

References

  • Sears M. L. Autonomic nervous system: adrenergic agonists. Handbook of Exptl. Pharmacol, M. L. Pp. Sears. Springer-Verlag, Berlin 1984; Vol. 69: 193–248
  • Potter D. E. Adrenergic pharmacology of aqueous humor dynamics. Pharmacol. Rev. 1981; 33: 133–153
  • Neufeld A. H. The mechanisms of action of adrenergic drugs in the eye. Glaucoma: Applied Pharmacology in Medical Treatment, S. M. Drance, A. H. Neufeld. Grune & Stratton, Orlando 1984; 277–324
  • Krieglstein G. K., Langham M. E., Leydhecker W. The peripheral and central actions of clonidine in normal and glaucomatous eye. Invest, Ophthalmol. Vis. Sci. 1978; 17: 149–158
  • Allen R. C., Langham M. E. The intraocular pressure response of conscious rabbits to clonidine. Invest. Ophthalmol. 1976; 15: 815–823
  • Innemee H. C., De Jonge A., van Meel J. C.A., Timmermans P. B.M.W.M., van Zwieten P. A. The effect of selective a 1-and a 2-adrenoceptor stimulation on intraocular pressure in the conscious rabbit. Naunyn-Schmiedeberg's Arch. Pharmacol. 1981; 316: 294–298
  • Langham M. E. The intraocular pressure and the pupillary responses of conscious rabbits to racemic erythro-α-methylnorepinephrine. Exp. Eye Res. 1984; 39: 781–790
  • Murray D. L., Leopold I. H. Alpha-adrenergic receptors in rabbit eyes. J. Ocular Pharmacol. 1985; 1: 3–18
  • Chiou G. C.Y. Effects of α1 and α2 activation of adrenergic receptors on aqueous humor dynamics. Life Sci. 1983; 32: 1699–1704
  • Thorig L., Hoyng P. F.J., Timmermans P. G.M.W.M., van Zwieten P. A. M-7 lowers rabbit intraocular pressure. Ophthalmic Res. 1985; 17: 362–372
  • Thorig L., Bill A. Effects of B-HT 920 in the eye and on regional blood flow in anaesthetized and conscious rabbits. Curr. Eye Res. 1986; 5: 565–573
  • Gherezghiher T., Koss M. C. Ocular effects of adrenergic stereoisomers in the rabbit. J. Ocular Pharmacol. 1985; 1: 19–28
  • Burke J. A., Potter D. E. Ocular effects of a relatively selective α2 agonist (UK-14,304–18) in cats, rabbits and monkeys. Curr. Eye Res. 1986; 5: 665–676
  • Starke K. Presynaptic receptors. Ann. Rev. Pharmacol. Toxicol. 1981; 21: 7–30
  • Westfall T. C. Local regulation of adrenergic neuotransmission. Physiol. Rev. 1977; 57: 659–728
  • Mittag T. W., Tormay A. Adrenergic receptor sybtypes in rabbit iris-ciliary body membranes: Classification by radioligand studies. Exp. Eye Res. 1985; 40: 239–249
  • Mittag T. W., Tormay A., Severin C., Podos S. M. Alpha-adrenergic antagonists: Correlation of the effect on intraocular pressure and on α2-adrenergic receptor binding specificity in trie rabbit eye. Exp. Eye Res. 1985; 40: 591–599
  • Mittag T. W., Tormay A. Drug responses of adenylate cyclase in iris-ciliary body determined by adenine labelling. Invest. Ophthalmol. Vis. Sci. 1985; 26: 396–399
  • Neufeld A. H., Page E. D. Regulation of adrenergic neuromuscular transmission in the rabbit iris. Exp. Eye Res. 1975; 20: 549–561
  • Jumblatt J. E., North G. T. Potentiation of sympathetic neurosecretion by forskolin and cyclic AMP in the rabbit irisciliary body. Curr. Eye Res. 1986; 5: 495–502
  • Scatchard G. The attraction of proteins for small molecules and ions. Ann. N.Y. Acad. Sci. 1949; 51: 660–672
  • Lowry O. H., Rosebrough N. J., Farr A. L., Randall R. J. Protein measurement with the folin reagent. J. Biol. Chem. 1951; 193: 265–275
  • Miller R. J., Freedman S. B. Are dihydropyridine binding sites voltage sensitive calcium channels?. Life Sci. 1984; 34: 1205–1221
  • Beattie D. T., Cunnane T. C., Muir T. C. Effects of calcium channel antagonists on action potential conduction and transmitter release in the guinea-pig vas deferens. Br. J. Pharmacol. 1986; 89: 235–244
  • Page E. D., Neufeld A. H. Characterization of α and β-adrenergic receptors in membranes prepared from the rabbit iris before and after development of supersensitivity. Biochem. Pharmacol. 1978; 27: 953–958
  • Rand M. J., McCulloch M. W., Story D. F. Feedback modulation of noradrenergic transmission. Trends in Pharm. Sci. 1982; 3: 8–11
  • Kalsner S. The presynaptic“receptor controversy. Trends in Pharm. Sci. 1982; 3: 11–16
  • Matthews W. D., Sulpizio A., Fowler P. J., DeMarinis R., Hieble J. P., Bergamini M. V.W. The ocular hypotensive action of SK&F 86466 in the conscious rabbit. Curr. Eye Res. 1984; 3: 737–742
  • Liu J. H.K., Nuefeld A. H. Study of central regulation of intraocular pressure using ventriculocisternal perfusion. Invest. Ophthalmol. Vis. Sci. 1985; 26: 136–143
  • Bausher L. P., Gregory D. S., Sears M. L. Interaction Between α2-and (β2-adrenergic receptors in rabbit ciliary processes. Invest. Ophthalmol. Vis. Sci. (ARVO suppl.) 1986; 27: 352
  • Yoshitomi T., Ito Y. Pre-synaptic actions of noradrenaline on the dog ciliary muscle tissue. Exp. Eye Res. 1986; 43: 119–127
  • Dubocovich M. L. a adrenoceptors modulate ‘3H’ dopamine release from rabbit retina. J. Pharmacol. Exp. Therap. 1984; 230: 149–155
  • Wetzel G. T., Brown J. H. Presynaptic modulation of acetylcholine release from cardiac parasympathetic neurons. Am. J. Physiol. 1985; 248: H33–H39
  • Capuzzo A., Borasio P. G., Fabbri E., Feretti M. E., Trevisani A. Alpha-adrenoceptor-mediated inhibition of acetylcholine release in guinea-pig superior cervical ganglion. Neuroscience Lett. 1983; 43: 215–219
  • Mittag T., Tormay A. Desensitization of the β-adrenergic receptor-adenylate cyclase complex in rabbit iris-ciliary body induced by topical epinephrine. Exp. Eye Res. 1981; 33: 497–503
  • Exton J. H. Molecular mechanisms involved in-adrenergic responses. Trends in Pharm. Sci. 1982; 3: 111–115
  • Canfield D. R., Dunlap K. Pharmacological characterization of amine receptors on embryonic chick sensory neurones. Br. J. Pharmacol. 1984; 82: 557–563
  • Holz G. C., Rane S. G., Dunlap K. GTP-binding proteins mediate transmitter inhibition of voltage-dependent calcium channels. Nature 1986; 319: 670–672

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