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Current Eye Research Volume 12, 1993 - Issue 10
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Original Article

Ocular renin angiotensin: EM immunocytochemical localization of prorenin

Ingolf H.L. Wallow Department of Ophthalmology and Visual Science, University of Wisconsin, Madison, WI, USA
,
Stephen J. Sramek Department of Ophthalmology and Visual Science, University of Wisconsin, Madison, WI, USA
,
Colleen D. Bindley Department of Ophthalmology and Visual Science, University of Wisconsin, Madison, WI, USA
,
Soesiawati R. Darjatmoko Department of Ophthalmology and Visual Science, University of Wisconsin, Madison, WI, USA
&
Stephen J. Gange Department of Ophthalmology and Visual Science, University of Wisconsin, Madison, WI, USA
Pages 945-950 | Received 17 Aug 1993, Accepted 21 Sep 1993, Published online: 02 Jul 2009

References

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  • Sealey J. E., Atlas S. A., Laragh J. H. Prorenin and other large molecular weight forms of renin. Endccr. Rev. 1980; 1: 365–391
  • Sealey J. E., White P., Laragh R. J.H., Rubin A. L. Plasma prorenin and renin in anephric patients. Circ. Res. 1977; 41(suppl II)17–21
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  • Sramek S. J., Wallow I. H.L., Day R. P., Ehrlich E. N. Ocular renin-angiotensin: Immunohistochemical evidence for the presence of prorenin in eye tissue. Invest. Ophthalmol. Vis. Sci. 1988; 29: 1749–1752
  • Tokuyasu K. T. Use of poly (vinyl pyrrohdone) and poly (vinyl alcohol) for cryo-ultramicrotomy. Histochem. J. 1989; 21: 163–171
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  • Taugner R., Kim S. J., Murakami K., Waldherr R. The fate of prorenin during granulopoiesis in epithelioid cells. Immunocytochemical experiments with antisera against renin and different portions of the rennin prosegment. Histochemistry 1987; 86: 249–253
  • Berka J. L.A., Alcorn D., Ryan G. B., Skinner S. L. Renin processing studied by immunogold localization of prorenin and renin in granular juxtaglomerular cells in mice treated with enalapril. Cell Tissue Res. 1992; 268: 141–148
  • Skett O. Episodic release of renin from single isolated perfused afferent arterioles. Huger's Arch. 1986; 407: 41–45
  • Paul M., Wagner J., Dzau V. J. Gene expression of the renin-angiotensin system in human tissues. Quantitative analysis by the polymerase chain reaction. J. Clin. Invest. 1993; 91: 2058–2064
  • Iwai N., Lnagami T. Quantitative analysis of renin gene expression in extrarend tissues by polymerase chain reaction method. J. Hypertension 1992; 10: 717–724

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