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Original Article

Cytochrome oxidase activity in bovine and human retinal pigment epithelium: topographical and age-related differences

Pages 1073-1079 | Received 22 Apr 1993, Accepted 01 Nov 1993, Published online: 02 Jul 2009

References

  • Dorey C. K., Wu G., Ebenstein D., Garsd A., Weiter J. J. Cell loss in the aging retina. Invest. Ophthalmol. Vis. Sci. 1989; 30: 1691–1699
  • Feeney-Burns L., Burns R. P., Gao C. -L. Age-related macular changes in humans over 90 years old. Am. J. Ophthalmol. 1990; 109: 265–278
  • Feeney-Burns L., Hilderbrand E. S., Eldridge S. Aging human RPE: morphometric analysis of macular, equatorial and peripheral cells. Invest. Ophthalmol. Vis. Sci. 1984; 25: 195–200
  • Gao H., Hollyfield J. G. Aging of the human retina. Differential loss of neurons and retinal pigment epithelial cells. Invest. Ophthalmol. Vis. Sci. 1992; 33: 1–17
  • Schmidt S. Y., Peisch R. D. Melanin concentration in normal human retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 1986; 27: 1063–1067
  • Weiter J. J., Delori F. C., Wing G. L., Fitch K. A. Retinal pigment epithelial lipofuscin and melanin and choroidal melanin in human eyes. Invest. Ophthalmol. Vis. Sci. 1986; 22: 145–152
  • Burke J. M., McKay B. S., Jaffe G. J. Retinal pigment epithelial cells of the posterior pole have fewer Na/K adenosine triphosphatase pumps than peripheral cells. Invest. Ophthalmol. Vis. Sci. 1991; 22: 2042–2046
  • Burke J. M., Soref C. Topographical variation in growth in cultured bovine retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 1988; 22: 1784–1788
  • Burke J. M., Twining S. S. Regional comparisons of cathepsin D activity in bovine retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 1988; 29: 1789–1793
  • Cabral L., Unger W., Boulton M., Lightfoot R., McKechnie N., Grierson I., Marshall J. Regional distribution of lysosomal enzymes in the canine retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 1990; 31: 670–676
  • Caldwell R. B., Slapnick S. M. Increased cytochrome oxidase activity in the diabetic rat retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 1989; 30: 591–599
  • Wong-Riley M. T. T. Cytochrome oxidase: an endogenous metabolic marker for neuronal activity. T.I.N.S. 1989; 12: 94–101
  • Goldstein S. Replicative senescence: the human fibroblast comes of age. Science 1990; 249: 1129–1133
  • Hayflick L. The cellular basis for biological aging. “Handbook of the Biology of Aging”, L. E. Finch, L. Hayflick. Van Nostrand Reinhold, New York 1977; 159–186
  • Hayflick L. Antecedents of cell aging research. Exp. Gerontol. 1989; 24: 355–365
  • Burke J. M., McKay B. S. In vitro aging of bovine and human retinal pigment epithelium: number and activity of the Na/K ATPase pump. Exp. Eye Res. 1993; 57: 51–57
  • Lowry O., Rosenbrough N., Farr A., Randall R. Protein measurement with the folin phenol reagent. J. Biol. Chem. 1951; 123: 265–275
  • Errede B., Kamen M. D., Haterfi Y. Preparation and properties of complex IV (ferrocytochrome c:oxygen oxidoreductase EC 1.9.3.1). Meth. Enzymol. 1978; 53: 40–47
  • Wharton D. C., Tzagoloff A. Cytochrome oxidase from beef heart mitochondria. Meth. Enzymol. 1967; 10: 245–250
  • Glocklin V. C., Potts A. M. The metabolism of retinal pigment cell epithelium. II. Respiration and glycolysis. Invest. Ophthalmol. 1965; 4: 226–234
  • Suson J. D., Nash R. W., McKay B. S., Burke J. M. Regional and sodium dependent variation in ATP and sodium pump number in RPE. Invest. Ophthalmol. Vis. Sci. 1993; 34(Suppl.)872
  • Linnane A. W., Baumer A., Maxwell R. J., Preston H., Zhang C., Marzuk S. Mitochondrial gene mutation: the ageing process and degenerative diseases. Biochem. Int. 1990; 22: 1067–1076

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