Advanced search
Publication Cover
Current Eye Research Volume 12, 1993 - Issue 12
Submit an article Journal homepage
6
Views
9
CrossRef citations to date
0
Altmetric
Original Article

The role of Igh-1 disparate congenic mouse T lymphocytes in the pathogenesis of herpetic stromal keratitis

Yonca A. Akova Hilles Immunology Laboratory, Massachusetts Eye & Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA, 02114, USA
,
James Dutt Hilles Immunology Laboratory, Massachusetts Eye & Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA, 02114, USA
,
Alejandro Rodriguez Hilles Immunology Laboratory, Massachusetts Eye & Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA, 02114, USA
,
Nada Jabbur Hilles Immunology Laboratory, Massachusetts Eye & Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA, 02114, USA
&
C. Stephen Foster Hilles Immunology Laboratory, Massachusetts Eye & Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA, 02114, USA
Pages 1093-1101 | Received 13 Sep 1993, Accepted 25 Oct 1993, Published online: 02 Jul 2009

References

  • Dawson C., Togni G. Herpes simplex eye infections; clinical manifestations, pathogenesis and management. Surv. Ophthalmol. 1976; 21: 11–29
  • Metcalf J. F., Kaufman H. E. Herpetic stromal keratitis evidence for cell-mediated immunopathogenesis. Am. J. Ophthalmol. 1976; 82: 827–834
  • Metcalf J. F., Hamilton D. S., Reichert R. W. Herpetic keratitis in athymic (nude) mice. Infect. Immun. 1979; 26: 164–171
  • Russell R. G., Nasisse M. P., Larsen H. S., Rouse B. T. Role of T-lymphocytes in the pathogenesis of herpetic stromal keratitis. Invest. Ophthalmol. Vis. Sci. 1984; 25: 938-–944
  • Newell C. K., Sendele D., Rouse B. T. Effects of CD4+ and CD8+ T-lymphocyte depletion on the induction and expression of herpes stromal keratitis. Reg. Immunol. 1989; 2: 366–369
  • Newell C. K., Martin S., Sendele D., Mercadal C. M., Rouse B. T. Herpes simplex virus-induced stromal keratitis: Role of T lymphocyte subsets in immunopathology. J. Virol. 1989; 63: 769–775
  • Doymaz M. Z., Rouse B. T. Herpetic stromal keratitis: an immunopathologic disease mediated by CD4+ T lymphocytes. Invest. Ophthalmol. Vis. Sci. 1992; 33: 2165–2175
  • Opremcak E. M., Wells P. A., Thompson P., Daigle J. A., Rice B. A., Millin J., Foster C. S. Immunogenetic influence of Igh-1 phenotype on experimental herpes simplex virus type-1 corneal infection. Invest. Ophthalmol. Vis. Sci. 1988; 29: 749–754
  • Foster C. S., Tsai Y., Monroe J. G., Campbell R. C., Cestari M., Knipe D., Greene M. I. Genetic studies on murine susceptibility to herpes simplex keratitis. Clin. Immunol. Immunopathol. 1986; 40: 313–25
  • Handbook for the use of animals in biomedical research. ARVO publication. Bethesda, MD, 2nd Ed. 1993; 15–16, Appendix A
  • NIH Guide for the Care and Use of Laboratory Animals. National Institutes of Health No. 85–23. 1985
  • Sandstrom I. K., Foster C. S., Wells P. A., Knipe D., Caron L., Greene M. I. Previous immunization of mice with herpes simplex virus type-1 strain MP protects against secondary corneal infection. Clin. Immunol. Immunopathol. 1986; 40: 326–334
  • Habu S., Fukui H., Shimamura M., Kasai M., Nagai Y., Okamura K., Tamaoki N. In vivo effects of anti-asialo GM1.1. Reduction of NK activity and enhancement of transplanted tumor growth in male mice. J. Immunol. 1981; 127: 34–38
  • Palmer D. F. Separation of peripheral blood lymphocytes in quantitation and functional assay of T and B cells. U. S. Dept. of Health, Education, and Welfare. Center for Disease Control, AtlantaGeorgia 1978; 6
  • Raizman M. B., Foster C. S. Passive transfer of anti-HSV-1 IgG protects against stromal keratitis in mice. Curr. Eye. Res. 1988; 7: 823–829
  • Opremcak E. M., Rice B. A., Wells B. A., Foster C. S. Histology and immunohistology of Igh-1-restricted herpes simplex keratitis in BALB/c congenic mice. Invest. Ophthalmol. Vis. Sci. 1990; 31: 305–312
  • Niemiatowski N. G., Rouse B. T. Phenotypic and functional studies on ocular T cells during herpetic infections of the eye. J. Immunol. 1992; 148: 1864–1870
  • Hendricks R. L., Tumpey T. M. Contribution of virus and immune factors to herpes simplex virus type 1-induced corneal pathology. Invest. Ophthalmol. Vis. Sci. 1990; 31: 1929–1939
  • Niemialtowsky M. G., Rouse B. T. Predominance of Th1 cells in ocular tas during herpetic stromal keratitis. J. Immunol. 1992; 149: 3035–3039
  • Foster C. S., Rodriguez A., Pedroza-Seres M., Berra A., Heiligenhaus A., Soukiasian S., Jayaraman S. Murine herpes simplex virus keratitis is accentuated by CD4+ Vb 8.2 Th2 T cells. Trans. Am. Ophthalmol. Soc. 1993, in press
  • Jayaraman S., Heiligenhaus A., Rodriguez A., Soukisasian S., Foster C. S. Exacerbation of murine herpes simplex virus-mediated stromal keratitis by Th2 type T cells. J. Immunol. 1993, in press
  • Thompson P., Wells P., Diagle J., Foster C. S. Herpes simplex virus type-1 keratitis is influenced by adoptive transfer of immune cells. Invest. Ophthalmol. Vis. Sci. 1986; 27(Supp.)47

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.