Effects of topical FK506 on endotoxin-induced uveitis (EIU) in the Lewis rat

References

• Rosenbaum J. T., McDevitt H. O., Guss R. B., Egbert P. R. Endotoxin-induced uveitis in rats as a model for human disease. Nature 1980; 286: 611–613
   PubMed Web of Science ®Google Scholar
• Kogiso M., Tanouchi Y., Mimura Y., Nagasawa H., Himeno K. Endotoxin-induced uveitis in mice. 1. Induction of uveitis and role of T lymphocytes. Jpn. J. Ophthalmol. 1992; 36: 281–290
   PubMed Web of Science ®Google Scholar
• Kulkarni P. S., Srinivasan B. D. Cachectin: A novel polypeptide induces uveitis in the rabbit eye. Exp. Eye Res. 1988; 46: 631–633
   PubMed Web of Science ®Google Scholar
• De Vos A. R., Hoekzema R., Kijlstra A. Cytokines and uveitis, a review. Curr. Eye Res. 1992; 11: 581–597
   PubMed Web of Science ®Google Scholar
• Yoshida M., Yoshimura N., Hangai M., Tanibara H., Honda Y. Interleukin-1α, interleukin-1β, and tumor necrosis factor gene expression in endotoxin-induced uveitis. Invest. Ophthalmol. Vis. Sci. 1994; 35: 1106–1113
   Google Scholar
• de Vos A. F., van Haren M. A. C., Verhagen C., Hoekzema R., Kijltra A. Kinetics of intraocular tumor necrosis factor and interleukin-6 in endotoxin-induced uveitis. Invest. Ophthalmol. Vis. Sci. 1994; 35: 1100–1106
   PubMed Web of Science ®Google Scholar
• Kino T., Hatanaka H., Miyata M., Inamura N., Nishiyama M., Yajima T., Goto T., Okuhara M., Kohsaka M., Aoki H., Ochiai T. FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics. J. Antibiot. 1987; 40: 1249–1255
   PubMed Web of Science ®Google Scholar
• Kino T., Imamura M., Sakai M., Nakahata K. Effect of FK-506 on human mixed lymphocyte reaction in vivo. Transpl. Proc. 1987; 19: 36–39, Suppl. 6
   PubMed Web of Science ®Google Scholar
• Kawano K., Kim Y. I., Kai T., Ishii T., Tatsuma T., Morimoto A., Tamura Y, Kobayashi M. Evidence that FK506 alleviates ischemia/reperfusion injury to the rat liver: In vivo demonstration for suppression of TNF-a production in response to endotoxemia. Eur. Surg. Res. 1994; 26: 108–115
   PubMedGoogle Scholar
• Chan C. C., Ni M., Miele L., Cordella-Miele E., Ferrick M., Mukherjee A. B., Nussenblatt R. B. Effects of antiflammins on endotoxin-induced uveitis in rats. Arch. Ophthalmol. 1991; 109: 278–281
   PubMedGoogle Scholar
• Li Q., Whitcup S. M., Fujino Y., Nussenblatt R. B., Chan C. C. The role of mast cells in endotoxin-induced uveitis. Invest. Ophthalmol. Vis. Sci. 1993; 34: 256–259
   PubMedGoogle Scholar
• Whitcup S. M., Hikita N., Shiro M., Miyasaki M., Mochizuki M., Nussenblatt R. B., Chan C. C. Monoclonal antibodies against CD54 and CD11a prevent and inhibit endotoxin-induced uveitis. Exp. Eye Res.
   Google Scholar
• Mochizuki M., Masuda K., Sakane T., Ito K., Kogure M., Sugino N., Usui M., Mizushima Y., Ohno S., Inaba G., Miyanaga Y., Hayasaka S., Oizumi K. A Clinical trial of FK506 in refractory uveitis. Am. J. Ophthalmol. 1993; 115: 763–769
   PubMed Web of Science ®Google Scholar
• Tocci M. J., Makovich D. A., Collier K. A., Kwok P., Domont F., Lin S., Degudicibus S., Siekierka J. J., Chin J., Huchinson N. I. The immunosuppressant FK-506 selectively inhibits expression of early T cell activation gene. J. Immunol. 1989; 143: 718–726
   PubMed Web of Science ®Google Scholar
• Keicho N., Sawada S., Kitamura K., Yotsumoto H., Takaku F. Effects of an immunosuppressant, FK506, on interleukin 1α production by human macrophages and a macrophage-like cell line, U937. Cell. Immunol. 1991; 132: 285–294
   PubMedGoogle Scholar
• Andersson J., Nagy S., Groth C. G., Andersson U. Effects of FK506 and cyclosporin A on cytokine production studied in vitro at a single-cell level. Immunology 1992; 75: 136–142
   PubMed Web of Science ®Google Scholar
• Yard B. A., Pancham R. R., Paape M. E., Daha M. R., van Es L. A., van der Woude F. J. CsA, FK506, corticosteroids and rapamycin inhibit TNFα production by cultured PTEC. Kidney Int. 1993; 44: 352–358
   PubMedGoogle Scholar
• Sakr M. F., McClain C. J., Gavaler J. S., Zetti A., ML G., Starzl T. E., Van Thil D. H. FK506-pre treatment is associated with reduced levels of tumor necrosis factor and interleukin 6 following hepatic ischemia/reperfusion. J. Hepatol. 1993; 17: 301–307
   PubMedGoogle Scholar
• Fujino Y., Chan C. C., de Smet M. D., Hikita N., Gery I., Mochizuki M., Nussenblatt R. B. FK506 treatment of experimental autoimmune uveoretinitis in primates. Transplant. Proc. 1991; 23: 3335–3338
   PubMedGoogle Scholar
• Tamura K., Woo J., Murase W. N., Carrieri G., Nalesnik M. A., Thomson A. W. Suppression of autoimmune thyroid disease by FK506: influence on thyroid-infiltrating cells, adhesion molecule expression and anti-thyroglobulin antibody production. Clin. Exp. Immunol. 1993; 91: 368–375
   PubMedGoogle Scholar
• Liversidge J., Thomson A. W., Forrester J. V. FK506 modulates accessory cell adhesion molecule expression and inhibits CD4 lymphocyte adhesion to retinal pigment epithelial cells in vitro: Implications for therapy of uveoretinitis. Transplant. Proc. 1991; 23: 3339–3342
   PubMedGoogle Scholar
• Thomson A. W., Nalesnik M. A., Rilo H. R., Woo J., Carroll P. B., Van Thiel D. H. ICAM-1 and E-selectin expression in lesional biopsies of psoriasis patients responding to systemic FK506 therapy. Autoimmunity 1993; 15: 215–223
   PubMed Web of Science ®Google Scholar
• Kawashima H., Fujino Y., Mochizuki M. Effect of new immunosuppressive agent, FK506, on experimental autoimmune uveoretinitis in rats. Invest. Ophthalmol. Vis. Sci. 1988; 29: 1265–1271
   PubMed Web of Science ®Google Scholar
• Ni M., Chan C. C., Nussenblatt R. B., Mochizuki M. FR900506(FK506) and 15-Deoxyspelguanin (15-DSG) modulate the kinetics of infiltrating cells in eyes with experimental autoimmune uveoretinitis. Autoimmunity 1990; 8: 43–51
   PubMed Web of Science ®Google Scholar
• Kasner L., Chan C. C., Whitcup S. M., Gery I. The paradoxical effect of tumor necrosis factor alpha (TNF-α) in endotoxin-induced uveitis. Invest. Ophthalmol. Vis. Sci. 1993; 34: 2911–2917
   PubMed Web of Science ®Google Scholar
• Sakr M., Zetti G., McClain C., Gavaler J., Nalesnik M., Todo S., Starzl T., Van Thiel D. The protective effect of FK506 pretreatment against renal ischemia/reperfusion injury in rats. Transplant. 1993; 53: 987–991
   Google Scholar
• Kim M. G., Palestine A. G., Nussenblatt R. B., Chan C. C. Expression of class II antigen in endotoxin induced uveitis. Curr. Eye Res. 1986; 5: 869–876
   PubMed Web of Science ®Google Scholar