Is Exhaled Nitric Oxide a Useful Adjunctive Test for Assessing Asthma?

References

• Expert Panel Report 3 (EPR-3): Guidelines for the Diagnosis and Management of Asthma-Summary Report 2007. J Allergy Clin Immunol. 2007; 120:S94–138.
   PubMed Web of Science ®Google Scholar
• Nathan RA, Sorkness CA, Kosinski M, Schatz M, Li JT, Marcus P, Murray JJ, Pendergraft TB. Development of the asthma control test: A survey for assessing asthma control. J Allergy Clin Immunol. 2004; 113:59–65.
   PubMed Web of Science ®Google Scholar
• Magadle R, Berar-Yanay N, Weiner P. The risk of hospitalization and near-fatal and fatal asthma in relation to the perception of dyspnea. Chest 2002; 121:329–333.
   PubMed Web of Science ®Google Scholar
• Alving K, Weitzberg E, Lundberg JM. Increased amount of nitric oxide in exhaled air of asthmatics. Eur Respir J. 1993; 6:1368–1370.
   PubMed Web of Science ®Google Scholar
• Kharitonov SA, Yates D, Robbins RA, Logan-Sinclair R, Shinebourne EA, Barnes PJ. Increased nitric oxide in exhaled air of asthmatic patients. Lancet 1994; 343:133–135.
   PubMed Web of Science ®Google Scholar
• Smith AD, Cowan JO, Filsell S, McLachlan C, Monti-Sheehan G, Jackson P, Taylor DR. Diagnosing asthma: comparisons between exhaled nitric oxide measurements and conventional tests. Am J Respir Crit Care Med. 2004; 169:473–478.
   PubMed Web of Science ®Google Scholar
• Smith AD, Cowan JO, Brassett KP, Filsell S, McLachlan C, Monti-Sheehan G, Peter Herbison G, Robin Taylor D. Exhaled nitric oxide: A predictor of steroid response. Am J Respir Crit Care Med. 2005; 172:453–459.
   PubMed Web of Science ®Google Scholar
• Smith AD, Cowan JO, Brassett KP, Herbison GP, Taylor DR. Use of exhaled nitric oxide measurements to guide treatment in chronic asthma. N Engl J Med. 2005; 352:2163–2173.
   PubMed Web of Science ®Google Scholar
• Jones SL, Kittelson J, Cowan JO, Flannery EM, Hancox RJ, McLachlan CR, Taylor D. The predictive value of exhaled nitric oxide measurements in assessing changes in asthma control. Am J Respir Crit Care Med. 2001; 164:738–743.
   PubMed Web of Science ®Google Scholar
• Shaw DE, Berry MA, Thomas M, Green RH, Brightling CE, Wardlaw AJ, Pavord ID. The use of exhaled nitric oxide to guide asthma management: a randomized controlled trial. Am J Respir Crit Care Med. 2007; 176:231–237.
   PubMed Web of Science ®Google Scholar
• Szefler SJ, Martin RJ, King TS, Boushey HA, Cherniack RM, Chinchilli VM, Craig TJ, Dolovich, Drazen JM, Fagan JK, Fahy JV, Fish JE, Ford JG, Israel E, Kiley J, Kraft M, Lazorus SC, Lemanske RF Jr, Mayger E, Peters SP, Sorkness CA, Asthma Clinical Research Network of the National Heart, Lung, and Blood Institute. Significant variability in response to inhaled corticosteroids for persistent asthma. J Allergy Clin Immunol 2002; 109:410–418.
   PubMed Web of Science ®Google Scholar
• Michils A, Baldassarre S, Van Muylem A. Exhaled nitric oxide and asthma control: A longitudinal study in unselected patients. Eur Respir J. 2008; 31:539–546.
   PubMed Web of Science ®Google Scholar
• Gelb AF, Flynn Taylor C, Shinar CM, Gutierrez C, Zamel N. Role of spirometry and exhaled nitric oxide to predict exacerbations in treated asthmatics. Chest 2006; 129:1492–1499.
   PubMed Web of Science ®Google Scholar
• Vega JM, Badia X, Badiola C, Lopez-Vina A, Olaguibel JM, Picado C, Sastre J, Dal-Ré R, Covalair Investigator Group. Validation of the Spanish version of the Asthma Control Test (ACT). J Asthma 2007; 44:867–872.
   PubMed Web of Science ®Google Scholar
• Menzies D, Nair A, Lipworth BJ. Portable exhaled nitric oxide measurement: Comparison with the “gold standard” technique. Chest 2007; 131:410–414.
   PubMed Web of Science ®Google Scholar
• Recommendations for standardized procedures for the on-line and off-line measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide in adults and children-1999. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999. Am J Respir Crit Care Med. 1999; 160:2104–2117.
   PubMed Web of Science ®Google Scholar
• ATS/ERS recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide, 2005. Am J Respir Crit Care Med. 2005; 171:912–930.
   PubMed Web of Science ®Google Scholar
• Standardization of Spirometry, 1994 Update. American Thoracic Society. Am J Respir Crit Care Med. 1995; 152:1107–1136.
   PubMed Web of Science ®Google Scholar
• Castellsague J, Burgos F, Sunyer J, Barbera JA, Roca J. Prediction equations for forced spirometry from European origin populations. Barcelona Collaborative Group on Reference Values for Pulmonary Function Testing and the Spanish Group of the European Community Respiratory Health Survey. Respir Med. 1998; 92:401–407.
   PubMed Web of Science ®Google Scholar
• Crapo RO. Pulmonary-function testing. N Engl J Med. 1994; 331:25–30.
   PubMed Web of Science ®Google Scholar
• Haldar P, Pavord ID, Shaw DE, Berry MA, Thomas M, Brightling CE, Wardlaw AJ, Green RH. Cluster analysis and clinical asthma phenotypes. Am J Respir Crit Care Med. 2008; 178:218–224.
   PubMed Web of Science ®Google Scholar
• Schatz M, Sorkness CA, Li JT, Marcus P, Murray JJ, Nathan RA, Kosinski M, Pendegraft TB, Jhingran P. Asthma Control Test: Reliability, validity, and responsiveness in patients not previously followed by asthma specialists. J Allergy Clin Immunol. 2006; 117:549–556.
   PubMed Web of Science ®Google Scholar
• Shirai T, Furuhashi K, Suda T, Chida K. Relationship of the asthma control test with pulmonary function and exhaled nitric oxide. Ann Allergy Asthma Immunol. 2008; 101:608–613.
   PubMed Web of Science ®Google Scholar
• Khalili B, Boggs PB, Shi R, Bahna SL. Discrepancy between clinical asthma control assessment tools and fractional exhaled nitric oxide. Ann Allergy Asthma Immunol. 2008; 101:124–129.
   PubMed Web of Science ®Google Scholar
• Lopes C, Fonseca J, Delgado L, Moreira A, Barros R, Moreira P, Castelo-Branco Mda G. Assessing asthma control: Questionnaires and exhaled nitric oxide provide complementary information. Eur Respir J. 2008; 32:1419–1420.
   PubMed Web of Science ®Google Scholar