598
Views
44
CrossRef citations to date
0
Altmetric
ASTHMA PHARMACOTHERAPEUTICS

Effect of Oral Magnesium Supplementation on Measures of Airway Resistance and Subjective Assessment of Asthma Control and Quality of Life in Men and Women with Mild to Moderate Asthma: A Randomized Placebo Controlled Trial

, Ph.D., , Ph.D., , M.D., M.P.H., Ph.D., , Ph.D & , Sc.D.
Pages 83-92 | Published online: 25 Jan 2010

REFERENCES

  • Britton J, Pavord I, Richards K, Wisniewski A, Knox A, Lewis S, Tattersfield A, Weiss S. Dietary magnesium, lung function, wheezing, and airway hyperreactivity in a random adult population sample. Lancet 1994; 344(8919):357–362.
  • Soutar A, Seaton A, Brown K. Bronchial reactivity and dietary antioxidants. Thorax 1997; 52:166–170.
  • Saris NE, Mervaala E, Karppanen H, Khawaja JA, Lewenstam A. Magnesium. An update on physiological, clinical and analytical aspects. Clin Chim Acta 2000; 294(1–2):1–26.
  • Ford ES, Mokdad AH. Dietary magnesium intake in a national sample of US adults. J Nutr 2003; 133:2879–2882.
  • Emelyanov A, Fedoseev G, Barnes PJ. Reduced intracellular magnesium concentrations in asthmatic patients. Eur Respir J 1999; 13:38–40.
  • Zervas E, Papatheodorou G, Psathakis K, Panagou P, Georgatou N, Loukides S. Reduced intracellular Mg concentrations in patients with acute asthma. Chest 2003; 123:113–118.
  • de Valk HW, Kok PT, Struyvenberg A, van Rijn HJ, Haalboom JR, Kreukniet J, Lammers JW. Extracellular and intracellular magnesium concentrations in asthmatic patients. Eur Respir J 1993; 6:1122–1125.
  • Fantidis P, Ruiz Cacho J, Marin M, Madero JR, Solera J, Herrero E. Intracellular (polymorphonuclear) magnesium content in patients with bronchial asthma between attacks. J R Soc Med 1995; 88:441–445.
  • Kazaks AG, Uriu-Adams JY, Albertson TE, Stern JS. Multiple measures of magnesium status are comparable in mild asthma and control subjects. J Asthma 2006; 43:783–788.
  • Landon RA, Young EA. Role of magnesium in regulation of lung function. J Am Diet Assoc 1993; 93:674–677.
  • Hill J, Micklewright A, Lewis S, Britton J. Investigation of the effect of short-term change in dietary magnesium intake in asthma. Eur Respir J 1997; 10:2225–2229.
  • Fogarty A, Lewis SA, Scrivener SL, Antoniak M, Pacey S, Pringle M, Britton J. Oral magnesium and vitamin C supplements in asthma: A parallel group randomized placebo-controlled trial. Clin Exp Allergy 2003; 33:1355–1359.
  • NHLBI. NAEPP Expert Panel Report: Guidelines for the Diagnosis and Management of Asthma–Update on Selected Topics 2002. 2002 [cited 5/2003]; Retrieved 7 June 2009 from http://www.nhlbi.nih.gov/guidelines/asthma/index.htm.
  • Juniper EF, O'Byrne PM, Ferrie PJ, King DR, Roberts JN. Measuring asthma control. Clinic questionnaire or daily diary? Am J Respir Crit Care Med 2000; 162(4 Pt 1):1330–1334.
  • Juniper EF, Guyatt GH, Cox FM, Ferrie PJ, King DR. Development and validation of the Mini Asthma Quality of Life Questionnaire. Eur Respir J 1999; 14:32–38.
  • Crapo RO, Casaburi R, Coates AL, Enright PL, Hankinson JL, Irvin CG, MacIntyre NR, McKay RT, Wanger JS, Anderson SD, . Guidelines for methacholine and exercise challenge testing-1999. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999. Am J Respir Crit Care Med 2000; 161:309–329.
  • Hankinson JL, Odencrantz JR, Fedan KB. Spirometric reference values from a sample of the general U.S. population. Am J Respir Crit Care Med 1999; 159:179–187.
  • King DE, Mainous AG, Geesey 3rd, ME, Woolson RF. Dietary magnesium and C-reactive protein levels. J Am Coll Nutr 2005; 24:166–171.
  • Alamoudi OS. Hypomagnesaemia in chronic, stable asthmatics: Prevalence, correlation with severity and hospitalization. Eur Respir J 2000; 16:427–431.
  • ATS, ATS/ERS Recommendations for Standardized Procedures for the Online and Offline Measurement of Exhaled Lower Respiratory Nitric Oxide and Nasal Nitric Oxide, 2005. Am J Respir Crit Care Med 2005; 171:912–930.
  • Rob PM, Dick K, Bley N, Seyfert T, Brinckmann C, Hollriegel V, Friedrich HJ, Dibbelt L, Seelig MS. Can one really measure magnesium deficiency using the short-term magnesium loading test? J Intern Med 1999; 246:373–378.
  • Chinn S, Schouten JP. Reproducibility of non-specific bronchial challenge in adults: Implications for design, analysis and interpretation of clinical and epidemiological studies. Thorax 2005; 60:395–400.
  • Cockcroft DW, Davis BE. Lack of tachyphylaxis to methacholine at 24 h. Chest 2005. 128:1248–1251.
  • Olivieri M, Talamini G, Corradi M, Perbellini L, Mutti A, Tantucci C, Malerba M. Reference values for exhaled nitric oxide (reveno) study. Respir Res 2006; 7:94.
  • Pearson TA, Mensah GA, Alexander RW, Anderson JL, Cannon RO, Criqui 3rd, M, Fadl YY, Fortmann SP, Hong Y, Myers GL, . Markers of inflammation and cardiovascular disease: Application to clinical and public health practice: A statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association. Circulation, 2003; 107:499–511.
  • Gontijo-Amaral C, Ribeiro MA, Gontijo LS, Condino-Neto A, Ribeiro JD. Oral magnesium supplementation in asthmatic children: A double-blind randomized placebo-controlled trial. Eur J Clin Nutr 2007; 61:54–60.
  • NHLBI. Expert panel report 3: Guidelines for the diagnosis and management of asthma 2007 [cited June 20, 2008]; Retrieved 7 June 2009 from http://www.nhlbi.nih.gov/guidelines/asthma/asthgdln.htm.
  • Masoli M, Fabian D, Holt S, Beasley R. The global burden of asthma: Executive summary of the GINA Dissemination Committee report. Allergy 2004; 59:469–478.
  • Stahl E. Correlation between objective measures of airway calibre and clinical symptoms in asthma: A systematic review of clinical studies. Respir Med 2000; 94:735–741.
  • Juniper EF, Svensson K, Mork AC, Stahl E. Measurement properties and interpretation of three shortened versions of the asthma control questionnaire. Respir Med 2005; 99:553–558.
  • Juniper EF, Price DB, Stampone PA, Creemers JP, Mol SJ, Fireman P. Clinically important improvements in asthma-specific quality of life, but no difference in conventional clinical indexes in patients changed from conventional beclomethasone dipropionate to approximately half the dose of extrafine beclomethasone dipropionate. Chest 2002; 121:1824–1832.
  • Ehrs PO, Sundblad BM, Larsson K. Quality of life and inflammatory markers in mild asthma. Chest 2006; 129:624–631.
  • Emel'ianov AV, Zinakova MK, Krasnoshchekova OI, Sinitsina TM, Rudinskii KA, Fedulov AV. Quality of life and characteristics of the external respiration function in patients with bronchial asthma. Ter Arkh 2001; 73:63–65.
  • Alving K, Weitzberg E, Lundberg JM. Increased amount of nitric oxide in exhaled air of asthmatics. Eur Respir J 1993; 6:1368–1370.
  • Kharitonov SA, Yates D, Robbins RA, Logan-Sinclair R, Shinebourne EA, Barnes PJ. Increased nitric oxide in exhaled air of asthmatic patients. Lancet 1994; 343(8890):133–135.
  • Zeidler MR, Kleerup EC, Tashkin DP. Exhaled nitric oxide in the assessment of asthma. Curr Opin Pulm Med 2004; 10:31–36.
  • al-Ali MK, Eames C, Howarth PH. Exhaled nitric oxide; relationship to clinicophysiological markers of asthma severity. Respir Med 1998; 92:908–913.
  • Kharitonov SA, Barnes PJ. Clinical aspects of exhaled nitric oxide. Eur Respir J. 2000; 16:781–792.
  • Dupont LJ, Rochette F, Demedts MG, Verleden GM. Exhaled nitric oxide correlates with airway hyperresponsiveness in steroid-naive patients with mild asthma. Am J Respir Crit Care Med 1998; 157(3 Pt 1):894–6898.
  • Jatakanon A, Lim S, Kharitonov SA, Chung KF, Barnes PJ. Correlation between exhaled nitric oxide, sputum eosinophils, and methacholine responsiveness in patients with mild asthma. Thorax 1998; 53:91–95.
  • Berkman N, Avital A, Breuer R, Bardach E, Springer C, Godfrey S. Exhaled nitric oxide in the diagnosis of asthma: Comparison with bronchial provocation tests. Thorax 2005; 60:383–388.
  • Kony S, Zureik M, Driss F, Neukirch C, Leynaert B, Neukirch F. Association of bronchial hyperresponsiveness and lung function with C-reactive protein (CRP): A population based study. Thorax 2004; 59:892–896.
  • Pepys MB, Hirschfield GM. C-reactive protein: A critical update. J Clin Invest 2003; 111:1805–1812.
  • Ford ES. Asthma, body mass index, and C-reactive protein among US adults. J Asthma 2003; 40:733–739.
  • Song Y, Ridker PM, Manson JE, Cook NR, Buring JE, Liu S. Magnesium intake, C-reactive protein, and the prevalence of metabolic syndrome in middle-aged and older U.S. women. Diabetes Care 2005; 28:1438–1444.
  • Olafsdottir IS, Gislason T, Thjodleifsson B, Olafsson I, Gislason D, Jogi R, Janson C. C reactive protein levels are increased in non-allergic but not allergic asthma: A multicentre epidemiological study. Thorax 2005; 60:451–454.
  • Bede O, Nagy D, Suranyi A, Horvath I, Szlavik M, Gyurkovits K. Effects of magnesium supplementation on the glutathione redox system in atopic asthmatic children. Inflamm Res 2008; 57:279–286.
  • Hashimoto Y, Nishimura Y, Maeda H, Yokoyama M. Assessment of magnesium status in patients with bronchial asthma. J Asthma 2000; 37:489–496.
  • Feillet-Coudray C, Coudray C, Tressol JC, Pepin D, Mazur A, Abrams SA, Rayssiguier Y. Exchangeable magnesium pool masses in healthy women: Effects of magnesium supplementation. Am J Clin Nutr 2002; 75:72–78.
  • Rowe BH, Camargo CA Jr. The role of magnesium sulfate in the acute and chronic management of asthma. Curr Opin Pulm Med 2008; 14:70–76.
  • IMFNB, Dietary Reference Intakes: Calcium, Phosphorus, Magnesium, Vitamin D and Fluoride. 1999, National Academy Press: Washington, DC.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.