Up-regulation of the Extrinsic Coagulation Pathway in Acute Asthma—A Case Study

References

• Chambers RC. Procoagulant signalling mechanisms in lung inflammation and fibrosis: novel opportunities for pharmacological intervention? Br J Pharmacol 2008; 153(Suppl 1):S367–S378.
   PubMedGoogle Scholar
• Holgate ST. Pathogenesis of asthma. Clin Exp Allergy 2008; 38:872–897.
   PubMed Web of Science ®Google Scholar
• Wagers SS, Norton RJ, Rinaldi LM, Bates JH, Sobel BE, Irvin CG. Extravascular fibrin, plasminogen activator, plasminogen activator inhibitors, and airway hyperresponsiveness. J Clin Invest 2004; 114:104–111.
   PubMed Web of Science ®Google Scholar
• Perrio MJ, Ewen D, Trevethick MA, Salmon GP, Shute JK. Fibrin formation by wounded bronchial epithelial cell layers in vitro is essential for normal epithelial repair and independent of plasma proteins. Clin Exp Allergy 2007; 37:1688–1700.
   PubMed Web of Science ®Google Scholar
• Persson CG, Erjefalt JS, Greiff L, Erjefalt I, Korsgren M, Linden M, Contribution of plasma-derived molecules to mucosal immune defence, disease and repair in the airways. Scand J Immunol 1998; 47:302–313.
   PubMed Web of Science ®Google Scholar
• Van Rensen EL, Hiemstra PS, Rabe KF, Sterk PJ. Assessment of microvascular leakage via sputum induction: the role of substance P and neurokinin A in patients with asthma. Am J Respir Crit Care Med 2002; 165:1275–1279.
   PubMedGoogle Scholar
• Ovanesov MV, Ananyeva NM, Panteleev MA, Ataullakhanov FI, Saenko EL. Initiation and propagation of coagulation from tissue factor-bearing cell monolayers to plasma: initiator cells do not regulate spatial growth rate. J Thromb Haemost 2005; 3:321–331.
   PubMedGoogle Scholar
• Kucharewicz I, Kowal K, Buczko W, Bodzenta-Lukaszyk A. The plasmin system in airway remodeling. Thromb Res 2003; 112:1–7.
   PubMed Web of Science ®Google Scholar
• Cho SH, Ryu CH, Oh CK. Plasminogen activator inhibitor-1 in the pathogenesis of asthma. Exp Biol Med (Maywood) 2004; 229:138–146.
   PubMed Web of Science ®Google Scholar
• Seeger W, Elssner A, Gunther A, Kramer HJ, Kalinowski HO. Lung surfactant phospholipids associate with polymerizing fibrin: loss of surface activity. Am J Respir Cell Mol Biol 1993; 9:213–220.
   PubMedGoogle Scholar
• Wygrecka M, Jablonska E, Guenther A, Preissner KT, Markart P. Current view on alveolar coagulation and fibrinolysis in acute inflammatory and chronic interstitial lung diseases. Thromb Haemost 2008; 99:494–501.
   PubMed Web of Science ®Google Scholar
• Krupiczojc MA, Scotton CJ, Chambers RC. Coagulation signalling following tissue injury: focus on the role of factor Xa. Int J Biochem Cell Biol 2008; 40:1228–1237.
   PubMed Web of Science ®Google Scholar
• Imokawa S, Sato A, Hayakawa H, Kotani M, Urano T, Takada A. Tissue factor expression and fibrin deposition in the lungs of patients with idiopathic pulmonary fibrosis and systemic sclerosis. Am J Respir Crit Care Med 1997; 156:631–636.
   PubMed Web of Science ®Google Scholar
• Wygrecka M, Markart P, Ruppert C, Petri K, Preissner KT, Seeger W, Cellular origin of pro-coagulant and (anti)-fibrinolytic factors in bleomycin-injured lungs. Eur Respir J 2007; 29:1105–1114.
   PubMed Web of Science ®Google Scholar
• Gunther A, Mosavi P, Heinemann S, Ruppert C, Muth H, Markart P, Alveolar fibrin formation caused by enhanced procoagulant and depressed fibrinolytic capacities in severe pneumonia. Comparison with the acute respiratory distress syndrome. Am J Respir Crit Care Med 2000; 161:454–462.
   PubMed Web of Science ®Google Scholar
• Schultz MJ, Millo J, Levi M, Hack CE, Weverling GJ, Garrard CS, Local activation of coagulation and inhibition of fibrinolysis in the lung during ventilator associated pneumonia. Thorax 2004; 59:130–135.
   PubMed Web of Science ®Google Scholar
• Gunther A, Mosavi P, Ruppert C, Heinemann S, Temmesfeld B, Velcovsky HG, Enhanced tissue factor pathway activity and fibrin turnover in the alveolar compartment of patients with interstitial lung disease. Thromb Haemost 2000; 83:853–860.
   PubMed Web of Science ®Google Scholar
• Idell S, Peters J, James KK, Fair DS, Coalson JJ. Local abnormalities of coagulation and fibrinolytic pathways that promote alveolar fibrin deposition in the lungs of baboons with diffuse alveolar damage. J Clin Invest 1989; 84:181–193.
   PubMed Web of Science ®Google Scholar
• Peyrol S, Cordier JF, Grimaud JA. Intra-alveolar fibrosis of idiopathic bronchiolitis obliterans-organizing pneumonia. Cell-matrix patterns. Am J Pathol 1990; 137:155–170.
   PubMedGoogle Scholar
• Terada M, Kelly EA, Jarjour NN. Increased thrombin activity after allergen challenge: a potential link to airway remodeling? Am J Respir Crit Care Med 2004; 169:373–377.
   PubMedGoogle Scholar
• Cho SH, Tam SW, Demissie-Sanders S, Filler SA, Oh CK. Production of plasminogen activator inhibitor-1 by human mast cells and its possible role in asthma. J Immunol 2000; 165:3154–3161.
   PubMed Web of Science ®Google Scholar
• Pizzichini MM, Pizzichini E, Clelland L, Efthimiadis A, Mahony J, Dolovich J, Sputum in severe exacerbations of asthma: kinetics of inflammatory indices after prednisone treatment. Am J Respir Crit Care Med 1997; 155:1501–1508.
   PubMed Web of Science ®Google Scholar
• Brims FJ, Chauhan AJ, Higgins B, Shute JK. Coagulation factors in the airways in moderate and severe asthma and the effect of inhaled steroids. Thorax 2009; 64:1037–1043.
   PubMed Web of Science ®Google Scholar
• GINA. Global Strategy for Asthma Management and Prevention. Global Initiative for Asthma (GINA) 2007. Available at: http://www.ginasthma.org.
   Google Scholar
• Belda J, Margarit G, Martinez C, Bellido-Casado J, Casan P, Torrejon M, Anti-inflammatory effects of high-dose inhaled fluticasone versus oral prednisone in asthma exacerbations. Eur Respir J 2007; 30:1143–1149.
   PubMed Web of Science ®Google Scholar
• Pizzichini MM, Pizzichini E, Efthimiadis A, Chauhan AJ, Johnston SL, Hussack P, Asthma and natural colds. Inflammatory indices in induced sputum: a feasibility study. Am J Respir Crit Care Med 1998; 158:1178–1184.
   PubMed Web of Science ®Google Scholar
• Sidelmann JJ, Gram J, Jespersen J, Kluft C. Fibrin clot formation and lysis: basic mechanisms. Semin Thromb Hemost 2000; 26:605–618.
   PubMed Web of Science ®Google Scholar
• Enhorning G. Surfactant in airway disease. Chest 2008; 133:975–980.
   PubMed Web of Science ®Google Scholar
• Yuda H, Adachi Y, Taguchi O, Gabazza EC, Hataji O, Fujimoto H, Activated protein C inhibits bronchial hyperresponsiveness and Th2 cytokine expression in mice. Blood 2004; 103:2196–2204.
   PubMed Web of Science ®Google Scholar
• Smiley ST, King JA, Hancock WW. Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4. J Immunol 2001; 167:2887–2894.
   PubMed Web of Science ®Google Scholar
• Wark PA, Gibson PG. Asthma exacerbations. 3: Pathogenesis. Thorax 2006; 61:909–915.
   PubMed Web of Science ®Google Scholar
• Mallia P, Johnston SL. How viral infections cause exacerbation of airway diseases. Chest 2006; 130:1203–1210.
   PubMed Web of Science ®Google Scholar
• Gilmour PS, Morrison ER, Vickers MA, Ford I, Ludlam CA, Greaves M, The procoagulant potential of environmental particles (PM10). Occup Environ Med 2005; 62:164–171.
   PubMed Web of Science ®Google Scholar
• Shinagawa K, Martin JA, Ploplis V, Castellino F. Coagulation factor Xa modulates airway remodeling in a murine model of asthma. Am J Respir Crit Care Med 2007; 175:136–143.
   PubMed Web of Science ®Google Scholar
• Schouten M, MA VDP, Levi M T VDP, JS VDZ. Early activation of coagulation after allergen challenge in patients with allergic asthma. J Thromb Haemost 2009; 7:1592–1594.
   PubMedGoogle Scholar
• Leigh R, Oyelusi W, Wiehler S, Koetzler R, Zaheer RS, Newton R, Human rhinovirus infection enhances airway epithelial cell production of growth factors involved in airway remodeling. J Allergy Clin Immunol 2008; 121:1238–1245.
   PubMed Web of Science ®Google Scholar