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Risk Factors for Asthma

Is elective cesarean section associated with a higher risk of asthma? A meta-analysis

, MD, PhD, , MD, , MD, , PhD, , MD & , MD, PhD
Pages 16-25 | Received 07 Feb 2014, Accepted 03 Aug 2014, Published online: 27 Aug 2014

References

  • Lumbiganon P, Laopaiboon M, Gulmezoglu AM, Souza JP, Taneepanichskul S, Ruyan P, Attygalle DE, et al. Method of delivery and pregnancy outcomes in Asia: the WHO global survey on maternal and perinatal health 2007–08. Lancet 2010;375:490–499
  • Menacker F, Hamilton BE. Recent trends in cesarean delivery in the United States. NCHS Data Brief 2010;35:1–8
  • Bergholt T, Ostberg B, Legarth J, Weber T. Danish obstetricians’ personal preference and general attitude to elective cesarean section on maternal request: a nation-wide postal survey. Acta Obstet Gynecol Scand 2004;83:262–266
  • Ecker J. Elective cesarean delivery on maternal request. JAMA 2013;309:1930–1936
  • NIH State of the Science Conference: cesarean delivery on maternal request. Adv Neonatal Care 2006;6:171–172
  • Grant EN, Wagner R, Weiss KB. Observations on emerging patterns of asthma in our society. J Allergy Clin Immunol 1999;104(Pt 2):S1–S9
  • Anandan C, Nurmatov U, van Schayck OC, Sheikh A. Is the prevalence of asthma declining? Systematic review of epidemiological studies. Allergy 2010;65:152–167
  • Thavagnanam S, Fleming J, Bromley A, Shields MD, Cardwell CR. A meta-analysis of the association between Caesarean section and childhood asthma. Clin Exp Allergy 2008;38:629–633
  • Werner A, Ramlau-Hansen CH, Jeppesen SK, Thulstrup AM, Olsen J. Caesarean delivery and risk of developing asthma in the offspring. Acta Paediatr 2007;96:595–596
  • Menezes AM, Hallal PC, Matijasevich AM, Barros AJ, Horta BL, Araujo CL, Gigante DP, et al. Caesarean sections and risk of wheezing in childhood and adolescence: data from two birth cohort studies in Brazil. Clin Exp Allergy 2011;41:218–223
  • Ramachandrappa A, Jain L. Elective cesarean section: its impact on neonatal respiratory outcome. Clin Perinatol 2008;35:373–393
  • Ali UA, Norwitz ER. Vacuum-assisted vaginal delivery. Rev Obstet Gynecol Winter 2009;2:5–17
  • Kero J, Gissler M, Gronlund MM, Kero P, Koskinen P, Hemminki E, Isolauri E. Mode of delivery and asthma – is there a connection? Pediatr Res 2002;52:6–11
  • DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986;7:177–188
  • Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ 2003;327:557–560
  • professionals Ssf. StataCorp LP 1996–2006. Available at: http://www.stata.com [last accessed 20 Jun 2006]
  • Braback L, Ekeus C, Lowe AJ, Hjern A. Confounding with familial determinants affects the association between mode of delivery and childhood asthma medication – a national cohort study. Allergy Asthma Clin Immunol 2013;9:14
  • Tollanes MC, Moster D, Daltveit AK, Irgens LM. Cesarean section and risk of severe childhood asthma: a population-based cohort study. J Pediatr 2008;153:112–116
  • Metsala J, Kilkkinen A, Kaila M, Tapanainen H, Klaukka T, Gissler M, Virtanen SM. Perinatal factors and the risk of asthma in childhood – a population-based register study in Finland. Am J Epidemiol 2008;168:170–178
  • Almqvist C, Cnattingius S, Lichtenstein P, Lundholm C. The impact of birth mode of delivery on childhood asthma and allergic diseases – a sibling study. Clin Exp Allergy 2012;42:1369–1376
  • Smith GC, Wood AM, White IR, Pell JP, Cameron AD, Dobbie R. Neonatal respiratory morbidity at term and the risk of childhood asthma. Arch Dis Child 2004;89:956–960
  • Magnus MC, Haberg SE, Stigum H, Nafstad P, London SJ, Vangen S, Nystad W. Delivery by Cesarean section and early childhood respiratory symptoms and disorders: the Norwegian mother and child cohort study. Am J Epidemiol 2011;174:1275–1285
  • Hakansson S, Kallen K. Caesarean section increases the risk of hospital care in childhood for asthma and gastroenteritis. Clin Exp Allergy 2003;33:757–764
  • Pistiner M, Gold DR, Abdulkerim H, Hoffman E, Celedon JC. Birth by cesarean section, allergic rhinitis, and allergic sensitization among children with a parental history of atopy. J Allergy Clin Immunol 2008;122:274–279
  • Park YH, Kim KW, Choi BS, Jee HM, Sohn MH, Kim KE. Relationship between mode of delivery in childbirth and prevalence of allergic diseases in Korean children. Allergy Asthma Immunol Res 2010;2:28–33
  • Juhn YJ, Weaver A, Katusic S, Yunginger J. Mode of delivery at birth and development of asthma: a population-based cohort study. J Allergy Clin Immunol 2005;116:510–516
  • van Beijsterveldt TC, Boomsma DI. Asthma and mode of birth delivery: a study in 5-year-old Dutch twins. Twin Res Hum Genet 2008;11:156–160
  • Salam MT, Margolis HG, McConnell R, McGregor JA, Avol EL, Gilliland FD. Mode of delivery is associated with asthma and allergy occurrences in children. Ann Epidemiol 2006;16:341–346
  • Roduit C, Scholtens S, de Jongste JC, Wijga AH, Gerritsen J, Postma DS, Brunekreef B, et al. Asthma at 8 years of age in children born by caesarean section. Thorax 2009;64:107–113
  • Maitra A, Sherriff A, Strachan D, Henderson J. Mode of delivery is not associated with asthma or atopy in childhood. Clin Exp Allergy 2004;34:1349–1355
  • Xu B, Pekkanen J, Jarvelin MR. Obstetric complications and asthma in childhood. J Asthma 2000;37:589–594
  • Bager P, Melbye M, Rostgaard K, Benn CS, Westergaard T. Mode of delivery and risk of allergic rhinitis and asthma. J Allergy Clin Immunol 2003;111:51–56
  • Nafstad P, Magnus P, Jaakkola JJ. Risk of childhood asthma and allergic rhinitis in relation to pregnancy complications. J Allergy Clin Immunol 2000;106:867–873
  • McKeever TM, Lewis SA, Smith C, Hubbard R. Mode of delivery and risk of developing allergic disease. J Allergy Clin Immunol 2002;109:800–802
  • Renz-Polster H, David MR, Buist AS, Vollmer WM, O'Connor EA, Frazier EA, Wall MA. Caesarean section delivery and the risk of allergic disorders in childhood. Clin Exp Allergy 2005;35:1466–1472
  • Bernsen RM, de Jongste JC, Koes BW, Aardoom HA, van der Wouden JC. Perinatal characteristics and obstetric complications as risk factors for asthma, allergy and eczema at the age of 6 years. Clin Exp Allergy 2005;35:1135–1140
  • Hancox RJ, Landhuis CE, Sears MR. Forceps birth delivery, allergic sensitisation and asthma: a population-based cohort study. Clin Exp Allergy 2013;43:332–336
  • van Nimwegen FA, Penders J, Stobberingh EE, Postma DS, Koppelman GH, Kerkhof M, Reijmerink NE, et al. Mode and place of delivery, gastrointestinal microbiota, and their influence on asthma and atopy. J Allergy Clin Immunol 2011;128:948–955 e941–e943
  • Davidson R, Roberts SE, Wotton CJ, Goldacre MJ. Influence of maternal and perinatal factors on subsequent hospitalisation for asthma in children: evidence from the Oxford record linkage study. BMC Pulm Med 2010;10:14
  • Keski-Nisula L, Harju M, Jarvelin MR, Pekkanen J. Vacuum-assisted delivery is associated with late-onset asthma. Allergy 2009;64:1530–1538
  • Chen YC, Tsai CH, Lee Y. Gestational medication use, birth conditions, and early postnatal exposures for childhood asthma. Clin Dev Immunol 2012;2012:913426
  • Bager P, Wohlfahrt J, Westergaard T. Caesarean delivery and risk of atopy and allergic disease: meta-analyses. Clin Exp Allergy 2008;38:634–642
  • Boutsikou T, Malamitsi-Puchner A. Caesarean section: impact on mother and child. Acta Paediatr 2011;100:1518–1522
  • Jaakkola JJ, Ahmed P, Ieromnimon A, Goepfert P, Laiou E, Quansah R, Jaakkola MS. Preterm delivery and asthma: a systematic review and meta-analysis. J Allergy Clin Immunol 2006;118:823–830
  • Bendiks M, Kopp MV. The relationship between advances in understanding the microbiome and the maturing hygiene hypothesis. Curr Allergy Asthma Rep 2013;13:487–494
  • Adlerberth I, Strachan DP, Matricardi PM, et al. Gut microbiota and development of atopic eczema in 3 European birth cohorts. J Allergy Clin Immunol 2007;120:343–350
  • Hallstrom M, Eerola E, Vuento R, Janas M, Tammela O. Effects of mode of delivery and necrotising enterocolitis on the intestinal microflora in preterm infants. Eur J Clin Microbiol Infect Dis 2004;23:463–470
  • Lin SY, Lee JT, Yang CC, Gau ML. Factors related to milk supply perception in women who underwent cesarean section. J Nurs Res 2011;19:94–101
  • Kull I, Melen E, Alm J, Hallberg J, Svartengren M, van Hage M, Pershagen G, et al. Breast-feeding in relation to asthma, lung function, and sensitization in young schoolchildren. J Allergy Clin Immunol 2010;125:1013–1019
  • Schlinzig T, Johansson S, Gunnar A, Ekstrom TJ, Norman M. Epigenetic modulation at birth – altered DNA-methylation in white blood cells after Caesarean section. Acta Paediatr 2009;98:1096–1099
  • Kauppila A, Koivisto M, Pukka M, Tuimala R. Umbilical cord and neonatal cortisol levels. Effect of gestational and neonatal factors. Obstet Gynecol 1978;52:666–672
  • Vazquez Nava F, Salas Ramirez E, Sanchez Nuncio HR, et al. Meconium aspiration syndrome, parental atopy and asthma symptoms in children under two years old. Rev Alerg Mex 2006;53:130–135

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