Advanced search
Publication Cover
Journal of Asthma Volume 25, 1988 - Issue 6
Submit an article Journal homepage
2
Views
2
CrossRef citations to date
0
Altmetric
Original Article

Inhibitory Effect of DG-5128 on Steroid-Dependent Asthma

Yasumasa Yoshie First Department of Internal Medicine Gunma, University School of Medicine, 3–39 Maebasi, Gunma, 371, Japan
,
Kunihiko Iizuka First Department of Internal Medicine Gunma, University School of Medicine, 3–39 Maebasi, Gunma, 371, Japan
&
Tsugio Nakazawa Department of Internal Medicine and College of Medical Care, Technology Gunma University, 3–39 Maebasi, Gunma, 371, Japan
Pages 321-324 | Published online: 02 Jul 2009

References

  • Szentivanyi A, Heim O, Schulte P. Changes in adrenoceptor densities in membranes of lung tissue and lymphocyte from patients with atopic diesase. Ann NY Acad Sci 1979; 322: 295–298
  • Starke K. Alpha-adrenoceptor subclassification. Rev Physiol Biochem Pharmacol 1981; 88: 199–236
  • Yamakawa K, Kigosi S, Muramatu I. The selectivity of DG-5128 as an alpha-2 adrenoceptor antagonist. Eur J Phamacol 1985; 106: 625–628
  • Kameda K, Kyama I, Abiko Y. Comparative study on the effects of a hypoglycemic 2-substituted-2-imidazoline derivative (DG-5128) and tolubutamide on insulin secretion from and insulin synthesis in isolated rat pancreatic islets. Biochem Biophys Acta 1981; 677: 263–268
  • Makino S, Ikemori K, Kasima T, Fukuda T. Comparison of cyclic adenosine monophosphate response of lymphocytes in normal and asthmatic subjects to norepinephrine and salbutamol. J Allergy Clin Immunol 1977; 59: 348–352
  • Murayama T, Ui M. Loss of the inhibitory function of the guanine nucleotide regulatory component of adenylate cyclase due to its ADP ribosylation by islet-activating protein, pertussis toxin, in adipocyte membranes. J Biol Chem 1983; 258: 3319–3326
  • Iizuka K, Yoshie Y, Matui S, Umegae Y, Fueki R, Kobayashi S, Nakazawa T. Investigation of the beta-adrenergic dysfunction of the hormone-sensitive adenylate cyclase system in asthmatic lymphocyte cell membranes. Jap J Allergol 1987; 36: 909–916
  • Galant S P, Allred S, Griffiths R. Characterization of adenylate cyclase activity in asthmatic neutrophil sonicates. Am Rev Respir Dis 1980; 122: 231–238
  • Yoshie Y, Iizuka K, Umegae Y, Kobayashi S, Nakazawa T. Inhibitory effect on an alpha-2 adrenoceptor antagonist (DG-5128) on intractable asthma. Jap J Allergol 1987; 36: 413–416
  • Iizuka K, Yoshie Y, Nakazawa T, Matsui S, Umegae Y, Fueki R, Kobayasi S. Cell membrane fluidity of lymphocytes in asthmatic patients. Jap J Allergol 1986; 35: 387–392
  • Gilman A G. G proteins and dual control of adenylate cyclase. Cell 1984; 36: 577–579
  • Rich K A, Codina J, Floyd G, Sekura R, Hilderandt J D, Iyengar R. Glucagon-induced heterologous desensitization of the MDCK cell adenylyl cyclase. J Biol Chem 1984; 259: 7893–7901

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.