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Acta Oncologica Volume 30, 1991 - Issue 5
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Original Article

Treatment of Metastatic Carcinoid Tumors and the Carcinoid Syndrome with Recombinant interferon Alpha

C. Doberauer Department of internal Medicine Cancer Research, University of Essen, Essen, Germany
,
B. Mengelkoch Department of internal Medicine Cancer Research, University of Essen, Essen, Germany
,
O. Kloke Department of internal Medicine Cancer Research, University of Essen, Essen, Germany
,
U. Wandl Department of internal Medicine Cancer Research, University of Essen, Essen, Germany
&
N. Niederle Department of internal Medicine Cancer Research, University of Essen, Essen, Germany
Pages 603-605 | Received 14 Sep 1990, Accepted 02 Dec 1990, Published online: 08 Jul 2009

References

  • Godwin JD. Carcinoid tumors. An analysis of 2837 cases. Cancer 1975; 36: 560–9
  • Bukowski R M, Johnson K G, Peterson R F, et al. A phase II trial of combination chemotherapy in patients with metastatic carcinoid tumors. Cancer 1987; 60: 2891–5
  • Öberg K, Funa K, Alm G. Effects of leukocyte interferon on clinical symptoms and hormone levels in patients with midgut carcinoid tumors and the carcinoid syndrome. N Engl J Med 1983; 309: 129–33
  • Öberg K, Norheim I, Lind E, et al. Treatment of malignant carcinoid tumors with human leukocyte interferon: long-term results. Cancer Treat Rep 1986; 70: 1297–304
  • Öberg K, Aim G, Magnusson A, et al. Treatment of malignant carcinoid tumors with recombinant interferon alpha-2b: development of neutralizing interferon antibodies and possible loss of antitumor activity. J Natl Cancer Inst 1989; 81: 531–5
  • Smith D B, Scarffe J H, Wagstaff J, Johnston RJ. Phase II trial of rDNA alpha 2b interferon in patients with malignant carcinoid tumor. Cancer Treat Rep 1987; 71: 1265–6
  • Nobin A, Lindblom A, Månsson B, Sundberg M. Interferon treatment in patients with malignant carcinoids. Acta Oncol 1989; 28: 445–9
  • Moertel C G, Rubin J, Kvols LK. Therapy of metastatic carcinoid tumor and the malignant carcinoid syndrome with recombinant leukocyte A interferon. J Clin Oncol 1989; 7: 865–8

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