References
- Peterson HI. Tumor blood flow compared with normal tissue blood flow. Tumor blood circulation: Angiogenesis, vascular morphology and blood flow of experimental and human tumors, H I Peterson. CRC Press, Inc., Boca Raton, Florida 1979; 103–14
- Reinhold HS. Physiological effects of hyperthermia. Application of hyperthermia in the treatment of cancer, R D Issels, W Wilmans. Springer-Verlag, Berlin 1988; vol. 107: 32–43, Recent Results Cancer Res
- Vaupel P. Oxygen supply to malignant tumors. Tumor blood circulation: Angiogenesis, vascular morphology and blood flow of experimental and human tumors, H I Peterson. CRC Press, Inc., Boca Raton, Florida 1979; 143–68
- Falk P. The vascular pattern of the spontaneous C3H mouse mammary carcinoma and its significance in radiation response and in hyperthermia. Eur J Cancer 1980; 16: 203–17
- Guichard M, Courdi A, Malaise EP. Experimental data on the radiobiology of solid tumours. Eur J Radiother 1980; 1: 171–91
- Moulder J E, Rockwell S. Hypoxic fractions of solid tumors. Int J Radiat Oncol Biol Phys 1984; 10: 695–712
- Bush RS. The significance of anaemia in clinical radiation therapy. Int J Radiat Oncol Biol Phys 1986; 12: 2047–50
- Dische S. Chemical sensitizers for hypoxic cells: A decade of experience in clinical radiotherapy. Radiother Oncol 1985; 3: 97–115
- Overgaard J. Sensitization of hypoxic tumour cells—Clinical experience. Int J Radiat Biol 1989; 56: 801–11
- Adams GE. Hypoxic cell sensitizers for radiotherapy. Cancer: A comprehensive treatise, F F Becker. Plenum Press, New York 1977; vol. 6: 181–223
- Teicher B A, Lazo J S, Sartorelli AC. Classification of antineoplastic agents by their selective toxicities towards oxygenated and hypoxic tumor cells. Cancer Res 1981; 41: 73–81
- Suit H D, Gerweck LE. Potential for hyperthermia and radiation therapy. Cancer Res 1979; 39: 2290–8
- Chaplin D J, Acker B. The effect of hydralazine on the tumor cytotoxicity of the hypoxic cell cytotoxin RSU-1069: Evidence for therapeutic gain. Int J Radiat Oncol Biol Phys 1987; 13: 579–85
- Horsman M R, Christensen K L, Overgaard J. Hydralazine induced enhancement of hyperthermic damage in a C3H mammary carcinoma in vivo. Int J Hyperthermia 1989; 5: 123–36
- Overgaard J. Simultaneous and sequential hyperthermia and radiation treatment of an experimental tumor and its surrounding normal tissue in vivo. Int J Radiat Oncol Biol Phys 1980; 6: 1507–17
- Sapirstein LA. Regional blood flow by fractional distribution of indicators. Am J Physiol 1958; 193: 161–8
- Cater D B, Grigson C MB, Watkinson DA. Changes of oxygen tension in tumors induced by vasoconstrictor and vasodilator drugs. Acta Radiol 1962; 58: 401–8
- Kruuv J A, Inch W R, McCredie JA. Blood flow and oxygenation of tumour in mice. II. Effect of vasodilator drugs. Cancer 1967; 20: 60–5
- Babbs C F, DeWitt D P, Voorhees W D, McCaw J S, Chan RC. Theoretical feasibility of vasodilator-enhanced local tumour heating. Eur J Cancer Clin Oncol 1982; 18: 1137–46
- Voorhees W D, Babbs CF. Hydralazine-enhanced selective heating of transmissible venereal tumor implants in dogs. Eur J Cancer Clin Oncol 1982; 18: 1027–33
- Chan R C, Babbs C F, Vetter R J, Lamar CH. Abnormal response of tumor vasculature to vasoactive drugs. J Natl Cancer Inst 1984; 72: 145–50
- Nussbaum G H, Babbs C F, Mintun MA. Results of a preliminary study of the potential of vasodilators for improving thermotherapy of deep-seated tumors. Int J Hyperthermia 1986; 2: 61–4
- Okunieff P, Kallinowski F, Vaupel P, Neuringer LJ. Effects of hydralazine-induced vasodilation on the energy metabolism of murine tumors studied by in vivo 31-P nuclear magnetic resonance spectroscopoy. J Natl Cancer Inst 1988; 80: 745–50
- Leier C V, Magorian R D, Desch C E, Thomson M J, Unveferth DV. Hydralazine and isosorbide dinitrate comparative regional hemodynamic effects when administered alone or in combination. Circulation 1981; 63: 102–9
- Nickerson M. Vasodilator drugs. The pharmacological basis of therapeutics5th ed., L S Goodman, A Gilman. MacMillan, New York 1975; 727–43
- Eddy H A, Casarett GW. Development of the vascular system in the hamster malignant neurilemmoma. Microvascular Res 1973; 6: 63–82
- Folkman J. The vascularization of tumors. Sci Am 1976; 234: 58–73
- Algire G H, Legallais F Y, Anderson BF. Vascular reactions of normal and malignant tissues in vivo. VI. the role of hypotension in the action of components of podophyllin on transplanted sarcomas. J Natl Cancer Inst 1954; 14: 879–93
- Vaupel P. Interrelationship between mean arterial blood flow and vascular resistance in solid tumor tissue of DS-carcinosar-coma. Experientia 1975; 31: 587–9
- Brown J M, Horsman M R, Zeman E M, Hirst V K, Lemmon ML. Enhancement of tumor cell toxicity by SR 4233 with hydralazine. Proceedings of the 8th International Congress of Radiation Research., E M Fielden, J F Fowler, J H Hendry, D Scott. Taylor and Francis, London 1987; 297
- Acker B, Lentle B, Chaplin DJ. The effect of hydralazine (apresoline) on blood flow in human tumours. Proceedings of the 8th International Congress of Radiation Research., E M Fielden, J F Fowler, J H Hendry, D Scott. Taylor and Francis, London 1987; 297