Measurement of Human Tumour Oxygenation Status by a Polarographic Needle Electrode: An analysis of inter- and intratumour heterogeneity

References

• Thomlinson R H, Gray L H. The histological structure of some human lung cancers and the possible implications for radiotherapy. Br J Cancer 1955; 9: 539–49
   PubMed Web of Science ®Google Scholar
• Overgaard J. Sensitization of hypoxic tumour cells—clinical experience. Int J Radiat Biol 1989; 56: 801–11
   PubMed Web of Science ®Google Scholar
• Kolstad P. Vascularisation, oxygen tension, and radiocurability in cancer of the cervix. Scandinavian University Books, Oslo 1968, Norwegian Monographs on Medical Science
   Google Scholar
• Kallinowski F, Zander R, Hoeckel M, Vaupel P. Tumour tissue oxygenation as evaluated by computerized-pO2-Histo-graphy. Int J Radiat Oncol Biol Phys 1990; 19: 953–61
   PubMed Web of Science ®Google Scholar
• Vaupel P, Schlenger K, Knopp C, Hoeckel M. Oxygenation of human tumours: Evaluation of tissue oxygen distribution in breast cancers by computerized O2 tension measurements. Cancer Res 1991; 51: 3316–22
   PubMed Web of Science ®Google Scholar
• Fleckenstein W, Jungblut J R, Suckfüll M. Distribution of oxygen pressure in the periphery and center of malignant head and neck tumours. Clinical oxygen pressure measurements II, A M Ehrly. Blackwell Ueberreuter Wiss, Berlin 1990; 81–90
   Google Scholar
• Vaupel P, Kallinowski F, Okunieff P. Blood flow, oxygen consumption and tissue oxygenation of human tumours. Adv Exp Med Biol 1990; 277: 895–905
   PubMedGoogle Scholar
• Hoeckel M, Schlenger K, Knopp C, Vaupel P. Oxygenation of carcinomas of the uterine cervix: Evaluated by computerized O2 tension measurements. Cancer Res 1991; 51: 6098–102
   PubMed Web of Science ®Google Scholar
• Lartigau E, Le Ridant A M, Lambin P. Oxygenation of head and neck tumours. Cancer 1993; 71: 2319–25
   PubMed Web of Science ®Google Scholar
• Falk S J, Ward R, Bleehen N M. The influence of carbogen breathing on tumour tissue oxygenation in man evaluated by computerized pO2 histography. Br J Cancer 1992; 66: 919–24
   PubMed Web of Science ®Google Scholar
• Gatenby R A, Kessler H B, Rosenblum J S. Oxygen distribution in squamous cell carcinoma metastases and its relationship to outcome of radiation therapy. Int J Radiat Oncol Biol Phys 1988; 14: 831–8
   PubMed Web of Science ®Google Scholar
• Höckel M, Knopp C, Schlenger K. Intratumoural pO2 predicts survival in advanced cancer of uterine cervix. Radio-ther Oncol 1993; 26: 45–50
   PubMed Web of Science ®Google Scholar
• Nordsmark M, Bentzen S M, Overgaard J. Inter- and intra-tumour variability in the oxygenation status of lymph-node metastases from head and neck cancer. Tumor oxygenation, P Vaupel, D K Kelleher, M Günderoth. Gustav Fischer Verlag, Stuttgart-New York 1994, in press
   Google Scholar
• Schramm U, Fleckenstein W, Weber C. Morphological assessment of skeletalmuscular injury caused by pO2 measurements with hypodermic needle probes. Clinical oxygen pressure measurement II, A M Ehrly. Blackwell Ueberreuter Wiss, Berlin 1990; 38–50
   Google Scholar
• BMDP Statistical Sofware Manual, W J Dixon, 1990; Vol. 2: 1135–55
   Google Scholar
• Singbartl G, Metzger G, Beister R, Stögbauer R. Investigation on reproducibility of intramuscular pO2 measurements in patients by means of the tissue pO2-Histograph KIMOC/ Sigma. Clinical oxygen pressure measurements II, A M Ehrly. Blackwell Ueberreuter Wiss, Berlin 1990; 25–9
   Google Scholar
• Martin L, Lartigau E, Weeger P. Changes in the oxygenation of head and neck tumours during carbogen breathing. Radiother Oncol 1993; 27: 123–30
   PubMed Web of Science ®Google Scholar
• Gray L H, Conger A D, Ebert M. The concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy. Br J Radiol 1953; 26: 638–48
   PubMed Web of Science ®Google Scholar
• Horsman M R, Khalil A A, Nordsmark M, Grau C, Overgaard J. Relationship between radiobiological hypoxia and direct estimates of tumour oxygenation in a mouse tumour model. Radiother Oncol 1993; 28: 69–71
   PubMed Web of Science ®Google Scholar
• Baumgartl H. Systematic imvestigations of needle electrode properties in polarographic measurements of local tissue pO2. Clinical oxygen pressure measurement, A M Ehrly, L Hauss, R Huch. Springer-Verlag, Berlin-Heidelberg 1987; 17–42
   Google Scholar