164
Views
8
CrossRef citations to date
0
Altmetric
Original Article

Reoxygenation in a C3H Mouse Mammary Carcinoma the importance of chronic rather than acute hypoxia

, &
Pages 325-328 | Received 25 Sep 1994, Accepted 13 Dec 1994, Published online: 08 Jul 2009

References

  • Guichard M, Courdi A, Malaise E P. Experimental data on the radiobiology of solid tumours. Eur J Radiother 1980; 1: 171–91
  • Moulder J E, Rockwell S. Hypoxic fractions of solid tumors. Int J Radiat Oncol Biol Phys 1984; 10: 695–712
  • Overgaard J, Horsman M R. Overcoming hypoxic cell radiore-sistance. Basic clinical radiobiology for radiation oncologists, G G Steel. Edward Arnold, London 1993; 163–72
  • Thomlinson R H, Gray L H. The histological structure of some human lung cancers and the possible implications for radiotherapy. Br J Cancer 1955; 9: 539–49
  • Brown J M. Evidence for acutely hypoxic cells in mouse tumours and a possible mechanism of reoxygenation. Br J Radiol 1979; 52: 650–6
  • Sutherland R M, Franko A J. On the nature of the radiobio-logically hypoxic fraction in tumors. Int J Radiat Oncol Biol Phys 1980; 6: 117–20
  • Chaplin D J, Durand R E, Olive P L. Acute hypoxia in tumors: implication for modifiers of radiation effects. Int J Radiat Oncol Biol Phys 1986; 12: 1279–82
  • Chaplin D J, Olive P L, Durand R E. Intermittent blood flow in a murine tumor: radiobiological effects. Cancer Res 1987; 47: 597–601
  • van Putten L M, Kallman R F. Oxygenation status of a trans-plantable tumor during fractionated radiation therapy. J Natl Cancer Inst 1968; 40: 441–51
  • Thomlinson R H. Changes of oxygenation in tumours in relation to irradiation. Front Radiat Ther Oncol 1968; 3: 109–21
  • Kallman R F. The phenomenon of reoxygenation and its implications for fractionated radiotherapy. Radiology 1972; 105: 135–42
  • Kallman R F, Dorie M J. Tumour oxygenation and reoxygenation during radiation therapy: their importance in predicting tumour response. Int J Radiat Oncol Biol Phys 1986; 12: 681–5
  • Rofstad E K. Hypoxia and reoxygenation in human melanoma xenografts. Int J Radiat Oncol Biol Phys 1989; 17: 81–9
  • Grau C, Horsman M R, Overgaard J. Improving the radiation response in a C3H mouse mammary carcinoma by normo-baric oxygen or carbogen breathing. Int J Radiat Oncol Biol Phys 1992; 22: 415–9
  • Horsman M R, Chaplin D J, Overgaard J. Combination of nicotinamide and hyperthermia to eliminate radioresistant chronically and acutely hypoxic tumor cells. Cancer Res 1990; 50: 7430–6
  • Horsman M R, Nordsmark M, Khalil A A, et al. Reducing acute and chronic hypoxia in tumours by combining nicotinamide with carbogen breathing. Acta Oncol 1994; 33: 371–6
  • Overgaard J. Simultaneous and sequential hyperthermia and radiation treatment of an experimental tumor and its surrounding normal tissue in vivo. Int J Radiat Oncol Biol Phys 1980; 6: 1507–17
  • Bentzen S M, Grau C. Direct estimation of the fraction of hypoxic cells from tumour-control data obtained under aerobic and clamped conditions. Int J Radiat Biol 1991; 59: 1435–40
  • Kim I H, Brown J M. Reoxygenation and rehypoxiation in the SCCVII mouse tumor. Int J Radiat Oncol Biol Phys 1994; 29: 493–7
  • Olive P. Radiation-induced reoxygenation in the SCCVII murine tumour: evidence for a decrease in oxygen consumption and an increase in tumour perfusion. Radiother Oncol 1994; 32: 37–46
  • Trotter M J, Chaplin D J, Durand R E, Olive P L. The use of fluorescent probes to identify regions of transient perfusion in murine tumours. Int J Radiat Oncol Biol Phys 1989; 16: 931–4
  • Grau C, Overgaard J. The influence of radiation dose on the magnitude and kinetics of reoxygenation in a C3H mammary carcinoma. Radiat Res 1990; 122: 309–15

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.