Chromosome 17q-Linkage Seems to be Infrequent in Icelandic Families at Risk of Breast Cancer

References

• Lynch H T, Marcus M M, Watson P, Conway T, Fritzsimmons M L, Lynch J F. Genetic epidemiology of breast cancer. Genetic epidemiology of cancer, H T Lynch, T Hirayama. CRC Press Inc., Boca Raton, Florida 1989; 289–332
   Google Scholar
• Easton D F, Bishop D T, Ford D, Crockford G P, The Breast Cancer Linkage Consortium. Genetic linkage analysis in familial breast and ovarian cancer: Results from 214 families. Am J Hum Genet 1993; 52: 678–701
   PubMed Web of Science ®Google Scholar
• Malkin D, Li F P, Strong L C, et al. Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science 1990; 250: 1233–8
   PubMed Web of Science ®Google Scholar
• Jolly K W, Malkin D, Douglas E C, Brown T F, Sinclair A E, Look A T. Splice-site mutation of the p53 gene in a family with hereditary breast-ovarian cancer. Oncogene 1994; 9: 97–102
   PubMed Web of Science ®Google Scholar
• Wooster R, Neuhausen S L, Mangion J, et al. Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13. Science 1994; 265: 2088–90
   PubMed Web of Science ®Google Scholar
• Narod S A, Ford D, Devilee P, et al. An evaluation of genetic heterogeneity in 145 breast-ovarian cancer families. Am J Hum Genet 1995; 56: 254–64
   PubMed Web of Science ®Google Scholar
• Börresen A.-L. Role of genetic factors in breast cancer susceptibility. Acta Oncol 1992; 31: 151–5
   PubMed Web of Science ®Google Scholar
• Swift M, Retinauer P J, Morrell D, Chase C L. Breast and other cancers in families with ataxia-telangiectasia. N Eng J Med 1987; 316: 1289–94
   PubMed Web of Science ®Google Scholar
• Swift M, Morrell D, Massey R B, Chase C L. Incidence of cancer in 161 families affected by ataxia-telangiectasia. N Eng J Med 1991; 325: 1831–6
   PubMed Web of Science ®Google Scholar
• Miki Y, Swensen J, Shattuck-Eidens D, et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 1994; 266: 66–71
   PubMed Web of Science ®Google Scholar
• Smith S A, Easton D F, Evans D GR, Ponder B. Allele losses in the region 17q12-21 in familial breast and ovarian cancer involve the wild-type chromosome. Nature Genet 1992; 2: 128–31
   PubMed Web of Science ®Google Scholar
• Cornelis R S, Neuhausen S L, Arason A, et al. Allele loss rates at 17q12-q21 in breast and ovarian tumors from 52 germline BRCA1-mutation carriers. Genes Chromosom Cancer 1995, (in press)
   Google Scholar
• Easton D F, Ford D, Bishop D T, Breast Cancer Linkage Consortium. Breast and ovarian cancer incidence in BRCA1 mutation carriers. Am J Hum Genet 1995; 56: 265–71
   PubMed Web of Science ®Google Scholar
• Arason A, Barkardóttir R B, Egilsson V. Linkage analysis of chromosome 17q markers and breast-ovarian cancer in Icelandic families, and possible relationship to prostatic cancer. Am J Hum Genet 1993; 52: 711–7
   PubMed Web of Science ®Google Scholar
• Tulinius H, Sigvaldason H, Ólafsdóttir G, Tryggvadóttir L. Epidemiology of breast cancer in families in Iceland. J Med Genet 1992; 29: 158–64
   PubMedGoogle Scholar
• Anderson L A, Friedman L, Osborne-Lawrence S, et al. High density genetic map of the BRCA1 region of chromosome 17q12-q21. Genomics 1993; 17: 618–23
   PubMedGoogle Scholar
• Vignal A, Gyapay G, Hazan J, . Nonradioactive multiplex procedure for genotyping of microsatellite markers. Methods in molecular genetics, vol. 1, Gene and chromosome analysis, Part A, K W Adolph, et al. Academic Press Inc, San DiegoCalifornia 1993; 211–21
   Google Scholar
• Weeks D E, Lange K. The affected-pedigree-member method of linkage analysis. Am J Hum Genet 1988; 42: 315–26
   PubMed Web of Science ®Google Scholar
• Stratton M R, Ford D, Neuhasen S, et al. Familial male breast cancer is not linked to the BRCA1 locus on chromosome 17q. Nature Genet 1994; 7: 103–7
   PubMed Web of Science ®Google Scholar
• Bergthorsson J T, Egilsson V, Gudmundsson J, et al. Identification of a breast tumor with microsatellite instability in a potential carrier of the hereditary non-polyposis colon cancer trait. Clin Genet 1995, (In press)
   PubMedGoogle Scholar