References
- Hollstein M, Sidransky D, Vogelstein B, Harris C C. p53 mutations in human cancer. Washington DC: Science 1991; 253: 49–53
- Hartwell L. Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells. Cell 1992; 71: 543–6
- Kuerbitz S J, Plunkett B S, Walsh W V, Kastan M B. Wild-type p53 is a cell cycle checkpoint determinant following irradiation. Proc Natl Acad Sci USA 1992; 89: 7491–5
- Waga S, Hannon G J, Beach D, Stillman B. The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature 1994; 369: 574–8
- Thorlacius S, Börresen A L, Eyfjörd J E. Somatic p53 mutations in human breast carcinomas in an Icelandic population: A prognostic factor. Cancer Res 1993; 53: 1637–41
- Börresen A L, Hovig E, Smith-Sörensen B, et al. Constant denaturant gel electrophoresis (CDGE) as a rapid screening technique for p53 mutations. Proc Natl Acad Sci USA 1991; 88: 8405–9
- Eyfjörd J E, Thorlacius S, Valgardsdottir R, Ögmundsdottir H M, Steinarsdottir M, Anamthawat-Jonsson K. P53 abnormalities and genomic instability in primary human breast carcinomas. Cancer Res 1995; 55: 646–51
- Ögmundsdóttir H M, Petursdottir I, Gudmundsdottir I, Amundadottir L, Rønnov-Jessen L, Petersen O W. Effects of lymphocytes and fibroblasts on the growth of human mammary carcinoma cell studies in short-term primary cultures. In Vitro Cell Dev Biol 1993; 29A: 936–42
- Steinarsdottir M, Snorradottir S, Petursdottir I, Anamthawat-Jonsson K, Eyfjörd J E, Ögmundsdottir H M. Different karyotypic profiles detected in breast carcinomas by direct harvesting and short term culture. Genes Chromosom Cancer 1995, (in press)
- Malkin D, Li F P, Strong L C, et al. Germ-line p53 mutations in a familial syndrome of breast cancer, sarcomas and other neoplasms. Washington DC: Science 1990; 250: 1233–8
- Eeles R A. Predictive testing for germline mutations in the p53 gene: Are all the questions answered?. Eur J Cancer 1993; 29A: 1361–5
- Börresen A L, Andersen T I, Malkin D, et al. Screening for germ line mutations in breast cancer patients. Cancer Res 1992; 52: 3234–6
- Yin Y, Tainsky M A, Bischoff F Z, Strong L C, Wahl G M. Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. Cell 1992; 70: 937–48
- Kastan M B, Zhan Q, El-Deiry W S, et al. A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. Cell 1992; 71: 587–97