312
Views
30
CrossRef citations to date
0
Altmetric
Original Article

Biophysical Aspects of Auger Processes

Pages 789-796 | Received 25 Aug 1995, Accepted 12 Jun 1996, Published online: 08 Jul 2009

References

  • Adelstein S. J. Biophysical aspects of Auger processes: a review of the literature 1987–1991. Biophysical aspects of Auger processes, R. W. Howell, V. R. Narra, K. S. R. Sastry, D. V. Rao. American Institute of Physics, Inc., Woodburry, NY 1992; 1–13
  • Auger P. Sur les rayons β secondaires produit dans un gaz des rayons X. Comp Rend 1925; 180: 65–8
  • Hofer K. G., Prensky W., Hughes W. L. Death and metastatic distribution of tumor cells in mice monitored with 125I-iodo-deoxyuridine. J Natl Cancer Inst 1969; 43: 763–73
  • Ertl H. H., Feinendegen L. E., Heiniger H. J. Iodine-125 a tracer in cell biology: physical properties and biological aspects. Phys Med Biol 1970; 15: 447–56
  • Feinendegen L. E., Ertl H. H., Bond V. P. Biological toxicity associated with the Auger effect. Proceedings of the Symposium on Biological Aspects of Radiation Quality, H. Ebert. IAEA., Vienna 1971; 419–30
  • Hofer K. G., Hughes W. L. Radiotoxicity of intranuclear tritium, iodine-125, and iodine-131. Radiat Res 1971; 47: 94–109
  • Smith E. M., Harris C. C., Rohrer R. H. Calculation of local energy deposition due to electron capture and internal conversion. J Nucl Med 1966; 7: 23–31
  • Gillespie F. C., Orr J. S., Greig W. R. Microscopic dose distribution from 1–125 in the toxic thyroid gland and its relation to therapy. Br J Radiol 1970; 43: 40–7
  • Charlton D. E., Booz J. A Monte Carlo treatment of the decay of '-sl. Radiat Res 1981; 87: 10–23
  • Kassis Al, Adelstein S. J., Haydock C., Sastry K. S. R. Radiotoxicity of Se-75 and S-35: theory and application to a cellular model. Radiat Res 1980; 84: 407–25
  • Kassis Al, Adelstein S. J., Haydock C., Sastry K. S. R., McElvany K. D., Welch M. J. Lethality of Auger electrons from the decay of bromide-77 in the DNA of mammalian cells. Radiat Res 1982; 90: 363–73
  • Rao D. V., Govelitz G. F., Sastry K. S. R. Radiotoxicity of thallium-201 in mouse testes: inadequacy of conventional dosimetry. J Nucl Med 1983; 34: 145–53
  • Rao D. V., Sastry K. S. R., Govelitz G. F., Grimmond H. E., Hill H. Z. In vivo effects of iron-55 and iron-59 on mouse testes: biophysical dosimetry of Auger electrons. J Nucl Med 1985; 26: 1456–65
  • Kassis AL, Sastry K. S. R., Adelstein S. J. Intracellular distribution and radiotoxicity of chromium-51 in mammalian cells: Auger electron dosimetry. J Nucl Med 1985; 26: 59–67
  • Rao D. V., Sastry K. S. R., Grimmond H. E., et al. Cytotoxicity of some indium radiopharmaceuticals in mouse testes. J Nucl Med 1988; 29: 375–84
  • Makrogiorgos G. M., Kassis Al, Baranowska-Kortylewicz J., et al. Radiotoxicity of 5-[I-125]iodo-2'-deoxyuridine in V79 cells: a comparison with 5-[I-123]iodo-2'-deoxyuridine. Radiat Res 1989; 118: 532–44
  • Howell R. W. Radiation spectra for Auger-electron emitting radionuclides: report No 2 of AAPM Nuclear Medicine Task Group No 6. Med Phys 1992; 19: 71–83
  • Humm J. L., Howell R. W., Rao D. V. Dosimetry of Auger-electron emitting radionuclides: report No 3 of AAPM Nuclear Medicine Task Group No 6. Med Phys 1994; 21: 1901–15
  • Weber D. A., Eckerman K. F., Dillman L. T., Ryman J. C. Radionuclide Data and Decay Schemes. Society of Nuclear Medicine, New York 1989, MIRD
  • Pomplun E., Booz J., Charlton D. E. A Monte Carlo simulation of Auger cascades. Radiat Res 1987; 111: 533–52
  • Krisch R. E., Ley R. D. Induction of lethality and DNA breakage by the decay of iodine-125 in bacteriophage T4. Int J Radiat Biol 1974; 25: 21–30
  • Krisch R. E., Krasin F., Sauri C. J. DNA breakage, repair, and lethality of 125I decay in rec+and recA strains of Escherichia coli. Int J Radiat Biol 1976; 29: 37–50
  • Painter R. B., Young B. R., Burki H. J. Non-repairable strand breaks induced by 125I incorporated into mammalian DNA. Proc Natl Acad Sci USA 1974; 71: 4836–8
  • Martin R. F., Haseltine W. A. Range of radiochemical damage to DNA with decay of iodine-125. Science 1981; 213: 896–8
  • Yasui L. S. Nuclear lesions produced by 125I decay. Biophysical aspects of Auger processes, R. W. Howell, V. R Narra, K. S. R. Sastry, D. V. Rao. American Institute of Physics, Inc., Woodburry, NY 1992; 210–26
  • Pomplun E. A new DNA target model for track structure calculations and its first application to I-125 Auger electrons. Int J Radiat Biol 1991; 59: 625–42
  • Paretzke H. G. Radiation track structure theory. Kinetics of inhomogeneous processes, G. R. Freeman. Wiley, New York 1987; 89–170
  • Pomplun E., Roch M., Terrissol M. Simulation of strand break induction by DNA incorporated 125I. Biophysical aspects of Auger processes, R. W. Howell, V. R. Narra, K. S. R. Sastry, D. V. Rao. American Institute of Physics, Inc., Woodburry, NY 1992; 137–52
  • Terrissol M. Modelling of radiation damage by 125l on a nucleosome. Int J Radiat Biol 1994; 66: 447–51
  • Pomplun E., Terrissol M. Low-energy electrons inside active DNA models: a tool to elucidate the radiation action mechanisms. Radiat Environ Biophys 1994; 33: 279–92
  • Charlton D. E., Humm J. L. A method of calculating initial DNA strand breakage following the decay of incorporated 125I. Int J Radiat Biol 1988; 53: 353–65
  • Makrigiorgos G. M., Berman R. M., Baranowska-Kortylewicz J., et al. DNA damage produced in V79 cells by DNA-incorporated iodine-123: a comparison with iodine-125. Radiat Res 1992; 129: 309–14
  • Sahu S. K., Kassis A. I., Makrigiorgos G. M., Baranowska-Kortylewicz J., Adelstein S. J. The effect of indium-111 decay on pBR322 DNA. Radiat Res 1995; 141: 193–8
  • Panyutin I. G., Neumann R. D. Sequence-specific DNA double-strand breaks induced by triplex forming 125I labeled oligonucleotides. Nucleic Acid Res 1994; 22: 4979–82
  • Miyazaki N., Fujiwara Y. Mutagenic and lethal effect of [5-125I]iodo-2'-deoxyuridine incorporated into DNA of mammalian cells and their RBEs. Radiat Res 1981; 88: 456–65
  • Little J. B., LeMotte P. K., Liber H. L. Quantitative studies of cytotoxicity, mutagenesis and oncologic transformation by radioisotopes incorporated into DNA. Human carcinogenesis, C. C. Harris, H. N. Auhup. Academic Press, New York 1983; 545–59
  • Chan P. C., Lisco E., Lisco H., Adelstein S. J. The radiotoxicity of iodine-125 in mammalian cells. II. A comparative study on cell survival and cytogenetic responses to 125IUdR 131IUdR and 3H-TdR. Radiat Res 1976; 67: 322–43
  • Sundell-Bergman S., Bergman R., Johanson K. J. Chromosome damage induced by decay of 3H and 125I incorporated into DNA of Chinese hamster cells. Mutat Res 1985; 149: 257–63
  • Warters R. L., Hofer K. G. Radionuclide toxicity in cultured mammalian cells: elucidation of the primary site for radiation-induced mitotic delay. Radiat Res 1977; 69: 348–58
  • Schneiderman M. H., Hofer K. G. The target for radiation-induced division delay. Radiat Res 1980; 84: 462–76
  • Hofer K. G. Radiation biology and potential therapeutic applications of radionuclides. Bull Cancer 1980; 67: 343–53
  • Hofer K. G., Harris C. R., Smith J. M. Radiotoxicity of intracellular 67Ga, 125I, and 3H: nuclear versus cytoplasmic radiation effects in murine LI210 leukemia. Int J Radiat Biol 1975; 28: 225–41
  • Warters R. L., Hofer K. G., Harris C. R., Smith J. M. Radionuclide toxicity in cultured mammalian cells: elucidation of the primary target of radiation damage. Curr Top Radiat Res Q 1977; 12: 389–407
  • Yasui L. S., Hofer K. G. Role of mitochondrial DNA in cell death induced by 125I decay. Int J Radiat Biol 1986; 49: 601–10
  • Hofer K. G., Keough G., Smith J. M. Biological toxicity of Auger emitters: molecular fragmentation vs. electron irradiation. Curr Top Radiat Res Q 1977; 12: 335–54
  • Makrigiorgos G. M., Adelstein S. J., Kassis A. L. Limitation of conventional internal dosimetry at the cellular level. J Nucl Med 1989; 30: 1856–64
  • Goddu S. M., Howell R. W., Rao D. V. Cellular dosimetry: absorbed fractions for monoenergetic electron and alpha particle sources and S-values for radionuclides uniformly distributed in different cell compartments. J Nucl Med 1994; 35: 305–16
  • Faraggi M., Gardin I., de Labriolle-Vaylet C., Moretti J. L., Bok B. D. The influence of tracer localization on the electron dose rate delivered to the cell nucleus. J Nucl Med 1994; 35: 113–9
  • Jonkhoff A. R., Dieren E. B., Huijgens P. C., et al. Biological effectiveness of 67-gallium in HL60 cells compared with external low dose rate gamma irradiation: effects on proliferation, G2 arrest, and clonogenic capacity. Int J Radiat Oncol Biol Phys 1994; 30: 117–24
  • Ludwikow G., Ludwikow F., Johanson K. J. Kinetics of microtubule induction by 125I-labeled thyroid hormone in hormone-responsive cells. Int J Radiat Biol 1992; 61: 639–53
  • Narra V. R., Howell R. W., Harapanhalli R. S., Sastry K. S. R., Rao D. V. Radiotoxicity of some iodine-123, iodine-125, and iodine-131-labeled compounds in mouse testes: implications for radiopharmaceutical design. J Nucl Med 1992; 33: 2196–201
  • Narra V. R., Howell R. W., Sastry K. S. R., Rao D. V. Auger electron emitters as tools for elucidating the location of primary radiosensitive targets. Radiat Prot Dosim 1994; 52: 229–32
  • Howell R. W., Rao D. V., Hou D. Y., Narra V. R., Sastry K. S. R. The question of relative biological effectiveness and quality factor for Auger emitters incorporated into proliferating mammalian cells. Radiat Res 1991; 128: 282–92
  • Kassis A. I., Makrigiorgos G. M., Adelstein S. J. Implications of radiobiologic and dosimetric studies of DNA-incorporated 123I: the use of the Auger effect as a biologic probe at the nanometre level. Radiat Prot Dosim 1990; 31: 333–8
  • Kassis A. I., Fayad F., Kinsey B. M., Sastry K. S. R., Adelstein S. J. Radiotoxicity of an I-125-labeled DNA intercalator in mammalian cells. Radiat Res 1989; 118: 283–94
  • McLean R. N., Wilkinson D. The radiation dose to cells in vitro from intracellular indium-Ill. Biochem Cell Biol 1989; 67: 661–5
  • Rao D. V., Narra V. R., Howell R. W., Lanka V. K., Sastry K. S. R. Induction of spermhead abnormalities by incorporated radionuclides: dependence on subcellular distribution, type of radiation, dose rate and presence of radioprotectors. Radiat Res 1991; 125: 89–97
  • Narra V. R., Harapanhalli R. S., Howell R. W., Sastry K. S. R., Rao D. V. Vitamins as radioprotectors in vivo: I. Protection by vitamin C against internal radionuclides in mouse testes: implications to the mechanism of the Auger effect. Radiat Res 1994; 137: 394–9
  • Narra V. R., Harapanhalli R. S., Goddu S. M., Howell R. W., Rao D. V. Radioprotection against biological effects of internal radionuclides in vivo by S-(2-aminoethyl)isothioronium bromide hydrobromide (AET). J Nucl Med 1995; 36: 259–66
  • Harapanhalli R. S., Narra V. R., Yaghmai V., et al. Vitamins as radioprotectors in vivo. II. Protection by vitamin A and soybean oil against radiation damage caused by internal radionuclides. Radiat Res 1994; 139: 115–22
  • Hofer K. G., VanLoon N., Schneiderman M. H., Charlton D. E. The paradoxical nature of DNA damage and cell death induced by 125I decay. Radiat Res 1992; 130: 121–4
  • Hofer K. G., VanLoon N., Schneiderman M. H., Charlton D. E. High LET and low LET cytocidal effects of DNA-associated iodine-125. Biophysical aspects of Auger processes, R. W. Howell, V. R. Narra, K. S. R. Sastry, D. V. Rao. American Institute of Physics, Inc., Woodburry, NY 1992; 227–48
  • Hofer K. G., Bao S. P. Low-LET and high-LET radiation action of 125I decays in DNA: effect of cysteamine on micronucleus formation and cell death. Radiat Res 1995; 141: 183–92
  • Howell R. W., Rao D. V., Sastry K. S. R. Macroscopic dosimetry for radioimmunotherapy: nonuniform activity distributions in solid tumors. Med Phys 1989; 16: 66–74
  • Strand S. E., Jönsson B. A., Ljungberg M., Tennvall J. Radioimmunotherapy dosimetry—a review. Acta Oncol 1993; 32: 807–17
  • Humm J. L., Macklis R. M., Lu X. Q., et al. The spatial accuracy of cellular dose estimates obtained from 3D reconstructed tissue autoradiographs. Phys Med Biol 1995; 40: 163–80
  • Schneiderman M. H., Schneidermann G. S. Radioiodo-deoxyuridine in cancer therapy: an in vitro approach to developing in vivo strategies. J Nucl Med 1996; 37((Suppl.))65–95
  • Klecker RW, Jr, Jenkins J. F., Kinsella T. J., Fine R. L., Strong J. M., Collins J. M. Clinical pharmacology of 5-iodo-2'-deoxyuridine and 5-iodouracil and endogenous pyrimidine modulation. Clin Pharmacol Ther 1985; 38: 45–51
  • Prusoff W. H. A review of some aspects of 5-125I-iodo-deoxyuridine and azauridine. Cancer Res 1963; 23: 1246–59
  • Van den Abbeele A. D., Baranowska-Kortylewicz J., Adelstein S. J., . Diagnostic and therapeutic applications of Auger electron emitting 5-[123I/125I]iodo-2'-deoxyuridine in cancer. Biophysical aspects of Auger processes, R. W. Howell, V. R. Narra, K. S. R. Sastry, D. V. Rao, et al. American Institute of Physics, Inc., Woodburry, NY 1992; 372–95
  • Kassis A. I., Van den Abbeele A. D., Wen P. Y. C., et al. Specific uptake of the Auger electron-emitting thymidine analogue 5-[123I/125I]iodo-2'-deoxyuridine in rat brain tumors: diagnostic and therapeutic implications in humans. Cancer Res 1990; 50: 5199–203
  • Mariani G., Cei A., Collechi P., et al. Tumor targeting in vivo and metabolic fate of 5-[iodo-125]-iodo-2'-deoxyuridine following intratumoral injection in patients with colorectal cancer. J Nucl Med 1993; 34: 1175–83
  • Mariani G., Giuliani L., Baranowska-Kortylewicz J., . Intratumoral injection of 5-[125I]iodo-2'-deoxyuridine in patients with breast cancer. Radioactive isotopes in clinical medicine and research, R. Höfer, H. Bergmann, H. Sinzinger, et al. Schattauer, Stuttgart—New York 1993; 188–93
  • Wheldon T. E. Targeting radiation to tumours. Int J Radiat Biol 1994; 65: 109–15
  • Bloomer W. D., McLaughlin W. H., Weichselbaum R. R., Hanson R. N., Adelstein S. J., Seitz D. E. The role of subcellular localization in assessing the cytotoxicity of iodine-125 labeled iodo-deoxyuridine iodotamoxifen and iodoantipyrine. J Radioanal Chem 1981; 65: 209–21
  • McLaughlin W. H., Milius R. A., Pillai K. M. R., Edasery J. P., Blu-Menthal RD, Bloomer W. D. Cytotoxicity of receptor-mediated 16α[125I]iodo-estradiol in cultured MCF-7 human breast cancer cells. J Natl Cancer Inst 1989; 81: 437–40
  • DeSombre E. R., Shan B., Hanson R. N., Kiuvanen P. C., Hughes A. Estrogen receptor-directed radiotoxicity with Auger electrons: specificity and mean lethal dose. Cancer Res 1992; 52: 5752–8
  • Ozanne B. W., Richards C. S., Hendler F. J., Burns D., Gustersen B. Over-expression of the EGF receptor is a hall-mark of squamous cell carcinomas. J Pathol 1986; 149: 9–14
  • Howell R. W., Kassis A. I., Adelstein S. J., et al. Radiotoxicity of platinum-195m-labeled trans-platinum (II) in mammalian cells. Radiat Res 1994; 140: 55–62
  • Helene C. The anti-gene strategy: control of gene expression by triplex-forming oligonucleotides. Anti-Cancer Drug Design 1991; 6: 569–84
  • Feinendegen L. E. Biological damage from the Auger effect possible benefits. Radiat Environ Biophys 1975; 12: 85–99

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.