187
Views
21
CrossRef citations to date
0
Altmetric
Original Article

Proliferation and DNA Aneuploidy in Mild Dysplasia Imply Early Steps of Cervical Carcinogenesis

Pages 3-12 | Received 28 Dec 1995, Accepted 10 Aug 1996, Published online: 08 Jul 2009

References

  • Zur Hausen H. Human papillomaviruses and their possible role in squamous cell carcinomas. Curr Top Microbiol Immunol 1977; 78: 1–30
  • Zur Hausen H. Papillomaviruses in human cancer. Cancer 1987; 59: 1692–6
  • Boveri T. Zur Frage der Entstehung maligner Tumoren. Gustav Fischer, Jena 1914
  • Âtkin N B, Richards B M. Deoxyribonucleic acid in human tumors as measured by microspectrophotometry of Feulgen stain: A comparison of tumors arising at different sites. Br J Cancer 1956; 10: 769–86
  • Caspersson O. Quantitative cytochemical studies on normal, malignant, premalignant and atypical cell populations from the human uterine cervix. Acta Cytol 1964; 8: 45–60
  • Wied G L, Messina A M, Meier P, Blough R R. Fluorospectrophotometric analysis on cervical epithelial cells. Acta Cytol 1964; 8: 61–7
  • Sandritter W. Methods and results in quantitative cytochemistry. Introduction to quantitative cytochemistry, G L Wied. Academic Press, New York 1966; vol 1: 159–82
  • Granberg I. Chromosomes in preinvasive, microinvasive and invasive cervical carcinoma. Hereditas 1971; 68: 165–218
  • Heselmeyer K, Schröck E, Du Manoir S, et al. Gain of chromosome 3q defines the transition from severe dysplasia to invasive carcinoma of the uterine cervix. Proc Natl Acad Sci USA 1996; 93: 479–84
  • Hall P A, Levison D A, Woods A L, et al. Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections as an index of cell proliferation with evidence of deregulated expression in some neoplasms. J Pathol 1990; 162: 285–94
  • Cattoretti G, Becker M HG, Key G, et al. Monoclonal antibodies against recombinant parts of the Ki-67 antigen (MIB-1 and MIB-3) detect proliferating cells in microwave-processed formalin-fixed paraffin sections. J Pathol 1992; 168: 357–63
  • Steinbeck R G, Heselmeyer K M, Moberger H B, Auer G U. The relationship between proliferating cell nuclear antigen (PCNA), nuclear DNA content and mutant p53 during genesis of cervical carcinoma. Acta Oncol 1995; 34: 171–5
  • Papanicolaou G N. A new procedure for staining vaginal smears. Science 1942; 95: 438–9
  • Soost H J. Befundwiedergabe in der gynäkologischen Zytodiagnostik: Münchner Nomenklatur, II. Gynäkol Prax 1990; 14: 433–8
  • Naujoks H F, Köpf F, Leber J. Präoperative kolposkopischzytologische Diagnostik bei zervikaler intraepithelialer Neoplasie (CIN). Geburtsh Frauenheilk 1979; 39: 372–7
  • Richart R M. A modified terminology for cervical intra-epithelial neoplasia. Obstet Gynecol 1990; 75: 131–3
  • Auer G, Caspersson T, Wallgren A. DNA content and survival in mammary carcinoma. Quant Cytol 1980; 2: 161–5
  • Jelen I, Valente P T, Gautreaux L, Clark G M. Deoxyribonucleic acid ploidy and S-phase fraction are not significant prognostic factors for patient with cervical cancer. Am J Obstet Gynecol 1994; 171: 1511–8
  • Kimmig R, Kapsner T, Spelsberg H, Untch M, Hepp H. DNA cell-cycle analysis of cervical cancer by flow cytometry using simultaneous cytokeratin labelling for identification of tumor cells. J Cancer Res Clin Oncol 1995; 121: 107–14
  • Moberger B. DNA content and prognosis in endometrial carcinoma. PhD Thesis. Karolinska Institute, Stockholm 1989
  • Ghali V S, Liau S, Teplitz C, Prudente R. A comparative study of DNA ploidy in 115 fresh-frozen breast carcinomas by image analysis versus flow cytometry. Cancer 1992; 70: 2668–72
  • Borgiani L, Cogorno P, Toso F, et al. Comparative DNA analysis of breast cancer by flow cytometry and image analysis. Pathologica 1994; 86: 356–9
  • Waldmann T, Lengauer C, Kinzler K W, Vogelstein B. Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21. Nature 1996; 381: 713–6
  • Sauer K, Knoblich J A, Richardson H, Lehner C F. Distinct modes of cyclin E/cdc2c kinase regulation and S-phase control in mitotic and endoreduplication cycles of Drosophila embryogenesis. Genes Development 1995; 9: 1327–39
  • Solomon D. The 1988 Bethesda system for reporting cervical/vaginal cytological diagnoses. Acta Cytol 1989; 33: 567–74
  • Solomon D. The revised Bethesda system for reporting cervical/vaginal cytologic diagnoses: Report of the 1991 Bethesda workshop. Acta Cytol 1992; 36: 273–6
  • Steinbeck R G, Moege J, Heselmeyer K M, et al. DNA content and PCNA immunoreactivity in oral precancerous and cancerous lesions. Oral Oncol Eur J Cancer 1993; 29 B: 279–84
  • Mihm M C, Jr, Lopansri S. A review of the classification of malignant melanoma. J Dermatol 1979; 6: 131–42

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.